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Items: 1 to 20 of 109


Delineation of the Cdc42/Rac-binding domain of p21-activated kinase.

Thompson G, Owen D, Chalk PA, Lowe PN.

Biochemistry. 1998 May 26;37(21):7885-91.


A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases.

Burbelo PD, Drechsel D, Hall A.

J Biol Chem. 1995 Dec 8;270(49):29071-4.


Structural requirements for PAK activation by Rac GTPases.

Knaus UG, Wang Y, Reilly AM, Warnock D, Jackson JH.

J Biol Chem. 1998 Aug 21;273(34):21512-8.


Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family.

Manser E, Chong C, Zhao ZS, Leung T, Michael G, Hall C, Lim L.

J Biol Chem. 1995 Oct 20;270(42):25070-8.


Possible involvement of the inactivation of the Rho-Rho-kinase pathway in oncogenic Ras-induced transformation.

Izawa I, Amano M, Chihara K, Yamamoto T, Kaibuchi K.

Oncogene. 1998 Dec 3;17(22):2863-71.


Vav transformation requires activation of multiple GTPases and regulation of gene expression.

Palmby TR, Abe K, Karnoub AE, Der CJ.

Mol Cancer Res. 2004 Dec;2(12):702-11.


Induction of postmitotic neuroretina cell proliferation by distinct Ras downstream signaling pathways.

Peyssonnaux C, Provot S, Felder-Schmittbuhl MP, Calothy G, Eychène A.

Mol Cell Biol. 2000 Oct;20(19):7068-79.


Cryptic Rac-binding and p21(Cdc42Hs/Rac)-activated kinase phosphorylation sites of NADPH oxidase component p67(phox).

Ahmed S, Prigmore E, Govind S, Veryard C, Kozma R, Wientjes FB, Segal AW, Lim L.

J Biol Chem. 1998 Jun 19;273(25):15693-701.


Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

Nimnual AS, Yatsula BA, Bar-Sagi D.

Science. 1998 Jan 23;279(5350):560-3.


Mechanisms of guanine nucleotide exchange and Rac-mediated signaling revealed by a dominant negative trio mutant.

Debreceni B, Gao Y, Guo F, Zhu K, Jia B, Zheng Y.

J Biol Chem. 2004 Jan 30;279(5):3777-86. Epub 2003 Nov 3.


Analysis of small GTPase signaling pathways using p21-activated kinase mutants that selectively couple to Cdc42.

Reeder MK, Serebriiskii IG, Golemis EA, Chernoff J.

J Biol Chem. 2001 Nov 2;276(44):40606-13. Epub 2001 Aug 20.


Cellular functions of TC10, a Rho family GTPase: regulation of morphology, signal transduction and cell growth.

Murphy GA, Solski PA, Jillian SA, Pérez de la Ossa P, D'Eustachio P, Der CJ, Rush MG.

Oncogene. 1999 Jul 1;18(26):3831-45.


PAK kinases are directly coupled to the PIX family of nucleotide exchange factors.

Manser E, Loo TH, Koh CG, Zhao ZS, Chen XQ, Tan L, Tan I, Leung T, Lim L.

Mol Cell. 1998 Jan;1(2):183-92.


Guanine nucleotide exchange factors regulate specificity of downstream signaling from Rac and Cdc42.

Zhou K, Wang Y, Gorski JL, Nomura N, Collard J, Bokoch GM.

J Biol Chem. 1998 Jul 3;273(27):16782-6.


CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1.

Lu X, Wu X, Plemenitas A, Yu H, Sawai ET, Abo A, Peterlin BM.

Curr Biol. 1996 Dec 1;6(12):1677-84.

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