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Items: 1 to 20 of 104

1.

Protein architecture, dynamics and allostery in tryptophan synthase channeling.

Pan P, Woehl E, Dunn MF.

Trends Biochem Sci. 1997 Jan;22(1):22-7. Review.

PMID:
9020588
2.

Allosteric regulation of tryptophan synthase channeling: the internal aldimine probed by trans-3-indole-3'-acrylate binding.

Casino P, Niks D, Ngo H, Pan P, Brzovic P, Blumenstein L, Barends TR, Schlichting I, Dunn MF.

Biochemistry. 2007 Jul 3;46(26):7728-39. Epub 2007 Jun 9.

PMID:
17559231
3.

Tryptophan synthase: the workings of a channeling nanomachine.

Dunn MF, Niks D, Ngo H, Barends TR, Schlichting I.

Trends Biochem Sci. 2008 Jun;33(6):254-64. doi: 10.1016/j.tibs.2008.04.008. Epub 2008 May 15. Review.

PMID:
18486479
4.

The tryptophan synthase bienzyme complex transfers indole between the alpha- and beta-sites via a 25-30 A long tunnel.

Dunn MF, Aguilar V, Brzović P, Drewe WF Jr, Houben KF, Leja CA, Roy M.

Biochemistry. 1990 Sep 18;29(37):8598-607.

PMID:
2271543
5.

Synergistic effects on escape of a ligand from the closed tryptophan synthase bienzyme complex.

Harris RM, Ngo H, Dunn MF.

Biochemistry. 2005 Dec 27;44(51):16886-95.

PMID:
16363802
6.

Tryptophan synthase: a multienzyme complex with an intramolecular tunnel.

Miles EW.

Chem Rec. 2001;1(2):140-51. Review.

PMID:
11893063
8.

Allostery and substrate channeling in the tryptophan synthase bienzyme complex: evidence for two subunit conformations and four quaternary states.

Niks D, Hilario E, Dierkers A, Ngo H, Borchardt D, Neubauer TJ, Fan L, Mueller LJ, Dunn MF.

Biochemistry. 2013 Sep 17;52(37):6396-411. doi: 10.1021/bi400795e. Epub 2013 Sep 6.

9.

Allosteric regulation of substrate channeling and catalysis in the tryptophan synthase bienzyme complex.

Dunn MF.

Arch Biochem Biophys. 2012 Mar 15;519(2):154-66. doi: 10.1016/j.abb.2012.01.016. Epub 2012 Feb 2. Review.

10.

Tryptophan synthase, an allosteric molecular factory.

Barends TR, Dunn MF, Schlichting I.

Curr Opin Chem Biol. 2008 Oct;12(5):593-600. doi: 10.1016/j.cbpa.2008.07.011.

PMID:
18675375
11.
12.

Structural and kinetic analysis of a channel-impaired mutant of tryptophan synthase.

Schlichting I, Yang XJ, Miles EW, Kim AY, Anderson KS.

J Biol Chem. 1994 Oct 28;269(43):26591-3.

13.
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16.

Allosteric regulation of substrate channeling in tryptophan synthase: modulation of the L-serine reaction in stage I of the beta-reaction by alpha-site ligands.

Ngo H, Kimmich N, Harris R, Niks D, Blumenstein L, Kulik V, Barends TR, Schlichting I, Dunn MF.

Biochemistry. 2007 Jul 3;46(26):7740-53. Epub 2007 Jun 9.

PMID:
17559232
18.

Synthesis and characterization of allosteric probes of substrate channeling in the tryptophan synthase bienzyme complex.

Ngo H, Harris R, Kimmich N, Casino P, Niks D, Blumenstein L, Barends TR, Kulik V, Weyand M, Schlichting I, Dunn MF.

Biochemistry. 2007 Jul 3;46(26):7713-27. Epub 2007 Jun 9.

PMID:
17559195
19.

Crystal structures of a new class of allosteric effectors complexed to tryptophan synthase.

Weyand M, Schlichting I, Marabotti A, Mozzarelli A.

J Biol Chem. 2002 Mar 22;277(12):10647-52. Epub 2001 Dec 26.

20.

Cooperative fluctuations and subunit communication in tryptophan synthase.

Bahar I, Jernigan RL.

Biochemistry. 1999 Mar 23;38(12):3478-90.

PMID:
10090734

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