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The related adhesion focal tyrosine kinase is tyrosine-phosphorylated after beta1-integrin stimulation in B cells and binds to p130cas.

Astier A, Avraham H, Manie SN, Groopman J, Canty T, Avraham S, Freedman AS.

J Biol Chem. 1997 Jan 3;272(1):228-32.


Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells.

ManiƩ SN, Beck AR, Astier A, Law SF, Canty T, Hirai H, Druker BJ, Avraham H, Haghayeghi N, Sattler M, Salgia R, Griffin JD, Golemis EA, Freedman AS.

J Biol Chem. 1997 Feb 14;272(7):4230-6.


The related adhesion focal tyrosine kinase differentially phosphorylates p130Cas and the Cas-like protein, p105HEF1.

Astier A, ManiƩ SN, Avraham H, Hirai H, Law SF, Zhang Y, Golemis EA, Fu Y, Druker BJ, Haghayeghi N, Freedman AS, Avraham S.

J Biol Chem. 1997 Aug 8;272(32):19719-24.


Stimulation of tyrosine phosphorylation after ligation of beta7 and beta1 integrins on human B cells.

Manie SN, Astier A, Wang D, Phifer JS, Chen J, Lazarovits AI, Morimoto C, Freedman AS.

Blood. 1996 Mar 1;87(5):1855-61.


Characterization of signal transduction pathways in human bone marrow endothelial cells.

Liu ZY, Ganju RK, Wang JF, Schweitzer K, Weksler B, Avraham S, Groopman JE.

Blood. 1997 Sep 15;90(6):2253-9.


p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase.

Harte MT, Hildebrand JD, Burnham MR, Bouton AH, Parsons JT.

J Biol Chem. 1996 Jun 7;271(23):13649-55.


Coupling of RAFTK/Pyk2 kinase with c-Abl and their role in the migration of breast cancer cells.

Zrihan-Licht S, Avraham S, Jiang S, Fu Y, Avraham HK.

Int J Oncol. 2004 Jan;24(1):153-9.


v-Crk-induced cell transformation: changes in focal adhesion composition and signaling.

Nievers MG, Birge RB, Greulich H, Verkleij AJ, Hanafusa H, van Bergen en Henegouwen PM.

J Cell Sci. 1997 Feb;110 ( Pt 3):389-99.


Integrin-mediated signal transduction in cells lacking focal adhesion kinase p125FAK.

Ueki K, Mimura T, Nakamoto T, Sasaki T, Aizawa S, Hirai H, Yano S, Naruse T, Nojima Y.

FEBS Lett. 1998 Aug 7;432(3):197-201.


P130Cas-associated protein (p140Cap) as a new tyrosine-phosphorylated protein involved in cell spreading.

Di Stefano P, Cabodi S, Boeri Erba E, Margaria V, Bergatto E, Giuffrida MG, Silengo L, Tarone G, Turco E, Defilippi P.

Mol Biol Cell. 2004 Feb;15(2):787-800. Epub 2003 Dec 2.


Direct binding of C-terminal region of p130Cas to SH2 and SH3 domains of Src kinase.

Nakamoto T, Sakai R, Ozawa K, Yazaki Y, Hirai H.

J Biol Chem. 1996 Apr 12;271(15):8959-65.


Src kinase plays an essential role in integrin-mediated tyrosine phosphorylation of Crk-associated substrate p130Cas.

Hamasaki K, Mimura T, Morino N, Furuya H, Nakamoto T, Aizawa S, Morimoto C, Yazaki Y, Hirai H, Nojima Y.

Biochem Biophys Res Commun. 1996 May 15;222(2):338-43.


Protein tyrosine phosphatase 1B negatively regulates integrin signaling.

Liu F, Sells MA, Chernoff J.

Curr Biol. 1998 Jan 29;8(3):173-6.


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