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Items: 1 to 20 of 152


Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras-Shc-Grb2 pathway.

Prigent SA, Nagane M, Lin H, Huvar I, Boss GR, Feramisco JR, Cavenee WK, Huang HS.

J Biol Chem. 1996 Oct 11;271(41):25639-45.


Involvement of ErbB2 in the signaling pathway leading to cell cycle progression from a truncated epidermal growth factor receptor lacking the C-terminal autophosphorylation sites.

Sasaoka T, Langlois WJ, Bai F, Rose DW, Leitner JW, Decker SJ, Saltiel A, Gill GN, Kobayashi M, Draznin B, Olefsky JM.

J Biol Chem. 1996 Apr 5;271(14):8338-44.


Shc phosphotyrosine-binding domain dominantly interacts with epidermal growth factor receptors and mediates Ras activation in intact cells.

Sakaguchi K, Okabayashi Y, Kido Y, Kimura S, Matsumura Y, Inushima K, Kasuga M.

Mol Endocrinol. 1998 Apr;12(4):536-43.


Interaction of Shc with Grb2 regulates association of Grb2 with mSOS.

Ravichandran KS, Lorenz U, Shoelson SE, Burakoff SJ.

Mol Cell Biol. 1995 Feb;15(2):593-600.


Functional importance of amino-terminal domain of Shc for interaction with insulin and epidermal growth factor receptors in phosphorylation-independent manner.

Sasaoka T, Ishihara H, Sawa T, Ishiki M, Morioka H, Imamura T, Usui I, Takata Y, Kobayashi M.

J Biol Chem. 1996 Aug 16;271(33):20082-7.


Specific involvement of tyrosine 764 of human granulocyte colony-stimulating factor receptor in signal transduction mediated by p145/Shc/GRB2 or p90/GRB2 complexes.

de Koning JP, Schelen AM, Dong F, van Buitenen C, Burgering BM, Bos JL, Löwenberg B, Touw IP.

Blood. 1996 Jan 1;87(1):132-40.


Sustained mitogen-activated protein kinase activation is induced by transforming erbB receptor complexes.

Wu CJ, Qian X, O'Rourke DM.

DNA Cell Biol. 1999 Oct;18(10):731-41.


A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides.

van der Geer P, Wiley S, Lai VK, Olivier JP, Gish GD, Stephens R, Kaplan D, Shoelson S, Pawson T.

Curr Biol. 1995 Apr 1;5(4):404-12.


Insulin and epidermal growth factor receptors regulate distinct pools of Grb2-SOS in the control of Ras activation.

Waters SB, Chen D, Kao AW, Okada S, Holt KH, Pessin JE.

J Biol Chem. 1996 Jul 26;271(30):18224-30.


Involvement of Shc in insulin- and epidermal growth factor-induced activation of p21ras.

Pronk GJ, de Vries-Smits AM, Buday L, Downward J, Maassen JA, Medema RH, Bos JL.

Mol Cell Biol. 1994 Mar;14(3):1575-81.


Shc, Grb2, Sos1, and a 150-kilodalton tyrosine-phosphorylated protein form complexes with Fms in hematopoietic cells.

Lioubin MN, Myles GM, Carlberg K, Bowtell D, Rohrschneider LR.

Mol Cell Biol. 1994 Sep;14(9):5682-91.


Internalized epidermal growth factor receptors participate in the activation of p21(ras) in fibroblasts.

Haugh JM, Huang AC, Wiley HS, Wells A, Lauffenburger DA.

J Biol Chem. 1999 Nov 26;274(48):34350-60.


Ras effector pathway activation by epidermal growth factor is inhibited in vivo by exoenzyme S ADP-ribosylation of Ras.

Henriksson ML, Rosqvist R, Telepnev M, Wolf-Watz H, Hallberg B.

Biochem J. 2000 Apr 1;347 Pt 1:217-22.


Comparison of the insulin and insulin-like growth factor 1 mitogenic intracellular signaling pathways.

Sasaoka T, Ishiki M, Sawa T, Ishihara H, Takata Y, Imamura T, Usui I, Olefsky JM, Kobayashi M.

Endocrinology. 1996 Oct;137(10):4427-34.


Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2.

VanderKuur J, Allevato G, Billestrup N, Norstedt G, Carter-Su C.

J Biol Chem. 1995 Mar 31;270(13):7587-93.

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