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Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth.

Yingling JM, Das P, Savage C, Zhang M, Padgett RW, Wang XF.

Proc Natl Acad Sci U S A. 1996 Aug 20;93(17):8940-4.


Functional cloning of the proto-oncogene brain factor-1 (BF-1) as a Smad-binding antagonist of transforming growth factor-beta signaling.

Rodriguez C, Huang LJ, Son JK, McKee A, Xiao Z, Lodish HF.

J Biol Chem. 2001 Aug 10;276(32):30224-30. Epub 2001 May 31.


Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling.

Souchelnytskyi S, Tamaki K, Engström U, Wernstedt C, ten Dijke P, Heldin CH.

J Biol Chem. 1997 Oct 31;272(44):28107-15.


Physical and functional interaction of murine and Xenopus Smad7 with bone morphogenetic protein receptors and transforming growth factor-beta receptors.

Souchelnytskyi S, Nakayama T, Nakao A, Morén A, Heldin CH, Christian JL, ten Dijke P.

J Biol Chem. 1998 Sep 25;273(39):25364-70.


Convergence of transforming growth factor-beta and vitamin D signaling pathways on SMAD transcriptional coactivators.

Yanagisawa J, Yanagi Y, Masuhiro Y, Suzawa M, Watanabe M, Kashiwagi K, Toriyabe T, Kawabata M, Miyazono K, Kato S.

Science. 1999 Feb 26;283(5406):1317-21.


The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase.

Kretzschmar M, Liu F, Hata A, Doody J, Massagué J.

Genes Dev. 1997 Apr 15;11(8):984-95.


MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma.

Eppert K, Scherer SW, Ozcelik H, Pirone R, Hoodless P, Kim H, Tsui LC, Bapat B, Gallinger S, Andrulis IL, Thomsen GH, Wrana JL, Attisano L.

Cell. 1996 Aug 23;86(4):543-52.


Smad pathway-specific transcriptional regulation of the cell cycle inhibitor p21(WAF1/Cip1).

Pardali K, Kowanetz M, Heldin CH, Moustakas A.

J Cell Physiol. 2005 Jul;204(1):260-72.


Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction.

Yamaguchi K, Shirakabe K, Shibuya H, Irie K, Oishi I, Ueno N, Taniguchi T, Nishida E, Matsumoto K.

Science. 1995 Dec 22;270(5244):2008-11.


Intracellular signaling of osteogenic protein-1 through Smad5 activation.

Tamaki K, Souchelnytskyi S, Itoh S, Nakao A, Sampath K, Heldin CH, ten Dijke P.

J Cell Physiol. 1998 Nov;177(2):355-63.


Endogenous patterns of TGFbeta superfamily signaling during early Xenopus development.

Faure S, Lee MA, Keller T, ten Dijke P, Whitman M.

Development. 2000 Jul;127(13):2917-31.


Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components.

Savage C, Das P, Finelli AL, Townsend SR, Sun CY, Baird SE, Padgett RW.

Proc Natl Acad Sci U S A. 1996 Jan 23;93(2):790-4.


Regulation of transforming growth factor beta- and activin-induced transcription by mammalian Mad proteins.

Chen Y, Lebrun JJ, Vale W.

Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):12992-7.

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