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The ribonucleotide reductase R1 subunits of herpes simplex virus types 1 and 2 protect cells against TNF╬▒- and FasL-induced apoptosis by interacting with caspase-8.

Dufour F, Sasseville AM, Chabaud S, Massie B, Siegel RM, Langelier Y.

Apoptosis. 2011 Mar;16(3):256-71. doi: 10.1007/s10495-010-0560-2.

PMID:
21107701
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A mutant type 2 herpes simplex virus deleted for the protein kinase domain of the ICP10 gene is a potent oncolytic virus.

Fu X, Tao L, Cai R, Prigge J, Zhang X.

Mol Ther. 2006 May;13(5):882-90. Epub 2006 Mar 29.

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