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Items: 1 to 20 of 157

1.

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules.

Rock KL, Gramm C, Rothstein L, Clark K, Stein R, Dick L, Hwang D, Goldberg AL.

Cell. 1994 Sep 9;78(5):761-71.

PMID:
8087844
2.
3.

Role of proteasomes in antigen presentation.

Gaczynska M, Rock KL, Goldberg AL.

Enzyme Protein. 1993;47(4-6):354-69. Review.

PMID:
7697133
4.

Novel dipeptide aldehydes are proteasome inhibitors and block the MHC-I antigen-processing pathway.

Harding CV, France J, Song R, Farah JM, Chatterjee S, Iqbal M, Siman R.

J Immunol. 1995 Aug 15;155(4):1767-75.

PMID:
7636233
5.

Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes.

Gaczynska M, Rock KL, Goldberg AL.

Nature. 1993 Sep 16;365(6443):264-7. Erratum in: Nature 1995 Mar 16;374(6519):290.

PMID:
8396732
6.

Proteolysis and class I major histocompatibility complex antigen presentation.

York IA, Goldberg AL, Mo XY, Rock KL.

Immunol Rev. 1999 Dec;172:49-66. Review.

PMID:
10631936
7.
8.
9.

Efficient presentation of both cytosolic and endogenous transmembrane protein antigens on MHC class II is dependent on cytoplasmic proteolysis.

Mukherjee P, Dani A, Bhatia S, Singh N, Rudensky AY, George A, Bal V, Mayor S, Rath S.

J Immunol. 2001 Sep 1;167(5):2632-41.

10.

The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides.

Goldberg AL, Cascio P, Saric T, Rock KL.

Mol Immunol. 2002 Oct;39(3-4):147-64. Review.

PMID:
12200047
12.

Antigen presentation by MHC class I and its regulation by interferon gamma.

Früh K, Yang Y.

Curr Opin Immunol. 1999 Feb;11(1):76-81. Review.

PMID:
10047537
13.

The role of the ubiquitin-proteasome pathway in MHC class I antigen processing: implications for vaccine design.

Sijts A, Zaiss D, Kloetzel PM.

Curr Mol Med. 2001 Dec;1(6):665-76. Review.

PMID:
11899255
14.

MHC-encoded proteasome subunits LMP2 and LMP7 are not required for efficient antigen presentation.

Yewdell J, Lapham C, Bacik I, Spies T, Bennink J.

J Immunol. 1994 Feb 1;152(3):1163-70.

PMID:
8301122
15.
16.

A role for the ubiquitin-dependent proteolytic pathway in MHC class I-restricted antigen presentation.

Michalek MT, Grant EP, Gramm C, Goldberg AL, Rock KL.

Nature. 1993 Jun 10;363(6429):552-4.

PMID:
8389422
17.

Rate of antigen degradation by the ubiquitin-proteasome pathway influences MHC class I presentation.

Grant EP, Michalek MT, Goldberg AL, Rock KL.

J Immunol. 1995 Oct 15;155(8):3750-8.

PMID:
7561079
18.

The specificity of proteasomes: impact on MHC class I processing and presentation of antigens.

Niedermann G, Geier E, Lucchiari-Hartz M, Hitziger N, Ramsperger A, Eichmann K.

Immunol Rev. 1999 Dec;172:29-48. Review.

PMID:
10631935
19.

Dissociation of proteasomal degradation of biosynthesized viral proteins from generation of MHC class I-associated antigenic peptides.

Antón LC, Snyder HL, Bennink JR, Vinitsky A, Orlowski M, Porgador A, Yewdell JW.

J Immunol. 1998 May 15;160(10):4859-68. Erratum in: J Immunol 1999 Mar 1;162(5):3105.

20.

Protein degradation and the generation of MHC class I-presented peptides.

Rock KL, York IA, Saric T, Goldberg AL.

Adv Immunol. 2002;80:1-70. Review.

PMID:
12078479

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