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Items: 1 to 20 of 74

1.
5.

The amyloidogenic pathway of amyloid precursor protein (APP) is independent of its cleavage by caspases.

Soriano S, Lu DC, Chandra S, Pietrzik CU, Koo EH.

J Biol Chem. 2001 Aug 3;276(31):29045-50. Epub 2001 Jun 7.

6.

Inhibition of receptor-mediated endocytosis demonstrates generation of amyloid beta-protein at the cell surface.

Chyung JH, Selkoe DJ.

J Biol Chem. 2003 Dec 19;278(51):51035-43. Epub 2003 Oct 2.

7.

Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities.

Citron M, Diehl TS, Gordon G, Biere AL, Seubert P, Selkoe DJ.

Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):13170-5.

9.

Flotillin-dependent clustering of the amyloid precursor protein regulates its endocytosis and amyloidogenic processing in neurons.

Schneider A, Rajendran L, Honsho M, Gralle M, Donnert G, Wouters F, Hell SW, Simons M.

J Neurosci. 2008 Mar 12;28(11):2874-82. doi: 10.1523/JNEUROSCI.5345-07.2008.

10.
11.

Cholesterol-like effects of selective cyclooxygenase inhibitors and fibrates on cellular membranes and amyloid-beta production.

Gamerdinger M, Clement AB, Behl C.

Mol Pharmacol. 2007 Jul;72(1):141-51. Epub 2007 Mar 29.

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15.

Inhibition of glycosphingolipid biosynthesis reduces secretion of the beta-amyloid precursor protein and amyloid beta-peptide.

Tamboli IY, Prager K, Barth E, Heneka M, Sandhoff K, Walter J.

J Biol Chem. 2005 Jul 29;280(30):28110-7. Epub 2005 May 27.

16.

Rab5-stimulated up-regulation of the endocytic pathway increases intracellular beta-cleaved amyloid precursor protein carboxyl-terminal fragment levels and Abeta production.

Grbovic OM, Mathews PM, Jiang Y, Schmidt SD, Dinakar R, Summers-Terio NB, Ceresa BP, Nixon RA, Cataldo AM.

J Biol Chem. 2003 Aug 15;278(33):31261-8. Epub 2003 May 20.

17.

The low density lipoprotein receptor-related protein 1B retains beta-amyloid precursor protein at the cell surface and reduces amyloid-beta peptide production.

Cam JA, Zerbinatti CV, Knisely JM, Hecimovic S, Li Y, Bu G.

J Biol Chem. 2004 Jul 9;279(28):29639-46. Epub 2004 May 4.

18.

Endocytic disturbances distinguish among subtypes of Alzheimer's disease and related disorders.

Cataldo A, Rebeck GW, Ghetri B, Hulette C, Lippa C, Van Broeckhoven C, van Duijn C, Cras P, Bogdanovic N, Bird T, Peterhoff C, Nixon R.

Ann Neurol. 2001 Nov;50(5):661-5.

PMID:
11706973
19.

The granulocyte macrophage colony stimulating factor (GM-CSF) regulates amyloid beta (Abeta) production.

Volmar CH, Ait-Ghezala G, Frieling J, Paris D, Mullan MJ.

Cytokine. 2008 Jun;42(3):336-44. doi: 10.1016/j.cyto.2008.03.007. Epub 2008 Apr 22.

PMID:
18434187
20.

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