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The transcriptional activator GCN4 contains multiple activation domains that are critically dependent on hydrophobic amino acids.

Drysdale CM, DueƱas E, Jackson BM, Reusser U, Braus GH, Hinnebusch AG.

Mol Cell Biol. 1995 Mar;15(3):1220-33.


Identification of seven hydrophobic clusters in GCN4 making redundant contributions to transcriptional activation.

Jackson BM, Drysdale CM, Natarajan K, Hinnebusch AG.

Mol Cell Biol. 1996 Oct;16(10):5557-71.


The N-terminal and C-terminal domains of RAP1 are dispensable for chromatin opening and GCN4-mediated HIS4 activation in budding yeast.

Yu L, Sabet N, Chambers A, Morse RH.

J Biol Chem. 2001 Aug 31;276(35):33257-64. Epub 2001 Jun 18.


Characterization of a p53-related activation domain in Adr1p that is sufficient for ADR1-dependent gene expression.

Young ET, Saario J, Kacherovsky N, Chao A, Sloan JS, Dombek KM.

J Biol Chem. 1998 Nov 27;273(48):32080-7.


Gcn2 mediates Gcn4 activation in response to glucose stimulation or UV radiation not via GCN4 translation.

Marbach I, Licht R, Frohnmeyer H, Engelberg D.

J Biol Chem. 2001 May 18;276(20):16944-51. Epub 2001 Feb 28.


A rice functional transcriptional activator, RISBZ1, responsible for endosperm-specific expression of storage protein genes through GCN4 motif.

Onodera Y, Suzuki A, Wu CY, Washida H, Takaiwa F.

J Biol Chem. 2001 Apr 27;276(17):14139-52. Epub 2000 Dec 22.


Cloning and characterization of a general amino acid control transcriptional activator from the chestnut blight fungus Cryphonectria parasitica.

Wang P, Larson TG, Chen CH, Pawlyk DM, Clark JA, Nuss DL.

Fungal Genet Biol. 1998 Feb;23(1):81-94.


Mutations activating the yeast eIF-2 alpha kinase GCN2: isolation of alleles altering the domain related to histidyl-tRNA synthetases.

Ramirez M, Wek RC, Vazquez de Aldana CR, Jackson BM, Freeman B, Hinnebusch AG.

Mol Cell Biol. 1992 Dec;12(12):5801-15.


Transcriptional activation mediated by the yeast AP-1 protein is required for normal cadmium tolerance.

Wemmie JA, Wu AL, Harshman KD, Parker CS, Moye-Rowley WS.

J Biol Chem. 1994 May 20;269(20):14690-7.


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