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Items: 1 to 20 of 85

1.

Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice.

Wakamiya M, Blackburn MR, Jurecic R, McArthur MJ, Geske RS, Cartwright J Jr, Mitani K, Vaishnav S, Belmont JW, Kellems RE, et al.

Proc Natl Acad Sci U S A. 1995 Apr 25;92(9):3673-7.

2.

Tissue-specific rescue suggests that placental adenosine deaminase is important for fetal development in mice.

Blackburn MR, Wakamiya M, Caskey CT, Kellems RE.

J Biol Chem. 1995 Oct 13;270(41):23891-4.

3.

Metabolic and immunologic consequences of limited adenosine deaminase expression in mice.

Blackburn MR, Datta SK, Wakamiya M, Vartabedian BS, Kellems RE.

J Biol Chem. 1996 Jun 21;271(25):15203-10.

4.

Adenosine-deaminase-deficient mice die perinatally and exhibit liver-cell degeneration, atelectasis and small intestinal cell death.

Migchielsen AA, Breuer ML, van Roon MA, te Riele H, Zurcher C, Ossendorp F, Toutain S, Hershfield MS, Berns A, Valerio D.

Nat Genet. 1995 Jul;10(3):279-87.

PMID:
7670465
5.

Function of murine adenosine deaminase in the gastrointestinal tract.

Xu PA, Kellems RE.

Biochem Biophys Res Commun. 2000 Mar 24;269(3):749-57.

PMID:
10720488
6.

The highest levels of purine catabolic enzymes in mice are present in the proximal small intestine.

Mohamedali KA, Guicherit OM, Kellems RE, Rudolph FB.

J Biol Chem. 1993 Nov 5;268(31):23728-33.

7.

Generation of normal lymphocyte populations following transplantation of adenosine-deaminase-deficient fetal liver cells.

Migchielsen AA, KnaƤn-Schanzer S, Breuer ML, Hershfield MS, Valerio D.

Bone Marrow Transplant. 1997 Jun;19(11):1137-43.

8.

Purine metabolism in adenosine deaminase deficiency.

Simmonds HA, Sahota A, Potter CF, Perrett D, Hugh-Jones K, Watson JG.

Ciba Found Symp. 1978;(68):255-62.

PMID:
387357
9.

Expression of human adenosine deaminase in mice reconstituted with retrovirus-transduced hematopoietic stem cells.

Wilson JM, Danos O, Grossman M, Raulet DH, Mulligan RC.

Proc Natl Acad Sci U S A. 1990 Jan;87(1):439-43.

10.

Requirement of the RNA editing deaminase ADAR1 gene for embryonic erythropoiesis.

Wang Q, Khillan J, Gadue P, Nishikura K.

Science. 2000 Dec 1;290(5497):1765-8.

12.

Recombinant adeno-associated virus-mediated gene transfer for the potential therapy of adenosine deaminase-deficient severe combined immune deficiency.

Silver JN, Elder M, Conlon T, Cruz P, Wright AJ, Srivastava A, Flotte TR.

Hum Gene Ther. 2011 Aug;22(8):935-49. doi: 10.1089/hum.2010.121. Epub 2011 Mar 13.

PMID:
21142972
13.
15.

Adenosine-mediated mast cell degranulation in adenosine deaminase-deficient mice.

Zhong H, Chunn JL, Volmer JB, Fozard JR, Blackburn MR.

J Pharmacol Exp Ther. 2001 Aug;298(2):433-40.

16.

Adenosine deaminase deficiency: metabolic basis of immune deficiency and pulmonary inflammation.

Blackburn MR, Kellems RE.

Adv Immunol. 2005;86:1-41. Review.

PMID:
15705418
17.
18.

Retroviral vector-mediated high-efficiency expression of adenosine deaminase (ADA) in hematopoietic long-term cultures of ADA-deficient marrow cells.

Bordignon C, Yu SF, Smith CA, Hantzopoulos P, Ungers GE, Keever CA, O'Reilly RJ, Gilboa E.

Proc Natl Acad Sci U S A. 1989 Sep;86(17):6748-52.

19.

Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction.

Blackburn MR, Volmer JB, Thrasher JL, Zhong H, Crosby JR, Lee JJ, Kellems RE.

J Exp Med. 2000 Jul 17;192(2):159-70.

20.

Establishment and characterization of adenosine deaminase-deficient human T cell lines.

Kohn DB, Mitsuya H, Ballow M, Selegue JE, Barankiewicz J, Cohen A, Gelfand E, Anderson WF, Blaese RM.

J Immunol. 1989 Jun 1;142(11):3971-7.

PMID:
2497184

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