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Items: 1 to 20 of 287

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Critical role of both p27KIP1 and p21CIP1/WAF1 in the antiproliferative effect of ZD1839 ('Iressa'), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells.

Di Gennaro E, Barbarino M, Bruzzese F, De Lorenzo S, Caraglia M, Abbruzzese A, Avallone A, Comella P, Caponigro F, Pepe S, Budillon A.

J Cell Physiol. 2003 Apr;195(1):139-50.

PMID:
12599217
5.

Deregulation of p53/p21Cip1/Waf1 pathway contributes to polyploidy and apoptosis of E1A+cHa-ras transformed cells after gamma-irradiation.

Bulavin DV, Tararova ND, Aksenov ND, Pospelov VA, Pospelova TV.

Oncogene. 1999 Oct 7;18(41):5611-9.

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Characterization of p21Cip1/Waf1 peptide domains required for cyclin E/Cdk2 and PCNA interaction.

Chen IT, Akamatsu M, Smith ML, Lung FD, Duba D, Roller PP, Fornace AJ Jr, O'Connor PM.

Oncogene. 1996 Feb 1;12(3):595-607.

PMID:
8637717
7.

Antisense oligonucleotide of WAF1 gene prevents EGF-induced cell-cycle arrest in A431 cells.

Ohtsubo M, Gamou S, Shimizu N.

Oncogene. 1998 Feb 12;16(6):797-802.

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Cyclin E-cdk2 activation is associated with cell cycle arrest and inhibition of DNA replication induced by the thymidylate synthase inhibitor Tomudex.

Yin MB, Guo B, Panadero A, Frank C, Wrzosek C, Slocum HK, Rustum YM.

Exp Cell Res. 1999 Feb 25;247(1):189-99.

PMID:
10047461
12.

Hyperoxia induces S-phase cell-cycle arrest and p21(Cip1/Waf1)-independent Cdk2 inhibition in human carcinoma T47D-H3 cells.

Bilodeau JF, Faure R, Piedboeuf B, Mirault ME.

Exp Cell Res. 2000 May 1;256(2):347-57.

PMID:
10772807
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Possible involvement of p21/waf1 in the growth inhibition of HepG2 cells induced by hepatocyte growth factor.

Shima N, Stolz DB, Miyazaki M, Gohda E, Higashio K, Michalopoulos GK.

J Cell Physiol. 1998 Oct;177(1):130-6.

PMID:
9731753
15.

Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade.

Levkau B, Koyama H, Raines EW, Clurman BE, Herren B, Orth K, Roberts JM, Ross R.

Mol Cell. 1998 Mar;1(4):553-63.

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The orphan receptor COUP-TFII regulates G2/M progression of breast cancer cells by modulating the expression/activity of p21(WAF1/CIP1), cyclin D1, and cdk2.

Nakshatri H, Mendonca MS, Bhat-Nakshatri P, Patel NM, Goulet RJ Jr, Cornetta K.

Biochem Biophys Res Commun. 2000 Apr 21;270(3):1144-53.

PMID:
10772965
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Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

Woods D, Parry D, Cherwinski H, Bosch E, Lees E, McMahon M.

Mol Cell Biol. 1997 Sep;17(9):5598-611.

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