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Items: 1 to 20 of 89

1.

Identification of non-coding genetic variants in samples from hypoxemic respiratory disease patients that affect the transcriptional response to hypoxia.

Roche O, Deguiz ML, Tiana M, Galiana-Ribote C, Martinez-Alcazar D, Rey-Serra C, Ranz-Ribeiro B, Casitas R, Galera R, Fernández-Navarro I, Sánchez-Cuéllar S, Bernard V, Ancochea J, Wasserman WW, García-Rio F, Jimenez B, Del Peso L.

Nucleic Acids Res. 2016 Nov 2;44(19):9315-9330. Epub 2016 Sep 12.

2.

Hypoxia as a target for tissue specific gene therapy.

Rhim T, Lee DY, Lee M.

J Control Release. 2013 Dec 10;172(2):484-94. doi: 10.1016/j.jconrel.2013.05.021. Epub 2013 Jun 3. Review.

PMID:
23742881
3.

Genome-wide mapping of Hif-1α binding sites in zebrafish.

Greenald D, Jeyakani J, Pelster B, Sealy I, Mathavan S, van Eeden FJ.

BMC Genomics. 2015 Nov 11;16:923. doi: 10.1186/s12864-015-2169-x.

4.

Destruction of a distal hypoxia response element abolishes trans-activation of the PAG1 gene mediated by HIF-independent chromatin looping.

Schörg A, Santambrogio S, Platt JL, Schödel J, Lindenmeyer MT, Cohen CD, Schrödter K, Mole DR, Wenger RH, Hoogewijs D.

Nucleic Acids Res. 2015 Jul 13;43(12):5810-23. doi: 10.1093/nar/gkv506. Epub 2015 May 24.

5.

6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia.

Obach M, Navarro-Sabaté A, Caro J, Kong X, Duran J, Gómez M, Perales JC, Ventura F, Rosa JL, Bartrons R.

J Biol Chem. 2004 Dec 17;279(51):53562-70. Epub 2004 Oct 5.

6.

Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen induction by hypoxia and hypoxia-inducible factors.

Veeranna RP, Haque M, Davis DA, Yang M, Yarchoan R.

J Virol. 2012 Jan;86(2):1097-108. doi: 10.1128/JVI.05167-11. Epub 2011 Nov 16.

7.

Hypoxia-inducible factor-1 (HIF-1) is a transcriptional activator of the TrkB neurotrophin receptor gene.

Martens LK, Kirschner KM, Warnecke C, Scholz H.

J Biol Chem. 2007 May 11;282(19):14379-88. Epub 2007 Mar 20.

8.

Transcriptional up-regulation of inhibitory PAS domain protein gene expression by hypoxia-inducible factor 1 (HIF-1): a negative feedback regulatory circuit in HIF-1-mediated signaling in hypoxic cells.

Makino Y, Uenishi R, Okamoto K, Isoe T, Hosono O, Tanaka H, Kanopka A, Poellinger L, Haneda M, Morimoto C.

J Biol Chem. 2007 May 11;282(19):14073-82. Epub 2007 Mar 12.

9.

Hypoxia-inducible factor-1α regulates KCNMB1 expression in human pulmonary artery smooth muscle cells.

Ahn YT, Kim YM, Adams E, Lyu SC, Alvira CM, Cornfield DN.

Am J Physiol Lung Cell Mol Physiol. 2012 Feb 1;302(3):L352-9. doi: 10.1152/ajplung.00302.2011. Epub 2011 Nov 23.

10.

Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1.

Semenza GL, Roth PH, Fang HM, Wang GL.

J Biol Chem. 1994 Sep 23;269(38):23757-63.

11.

Hypoxia-inducible factor 3 biology: complexities and emerging themes.

Duan C.

Am J Physiol Cell Physiol. 2016 Feb 15;310(4):C260-9. doi: 10.1152/ajpcell.00315.2015. Epub 2015 Nov 11. Review.

12.

Transcriptional regulation mechanisms of hypoxia-induced neuroglobin gene expression.

Liu N, Yu Z, Xiang S, Zhao S, Tjärnlund-Wolf A, Xing C, Zhang J, Wang X.

Biochem J. 2012 Apr 1;443(1):153-64. doi: 10.1042/BJ20111856.

PMID:
22239089
13.

An oxidative DNA "damage" and repair mechanism localized in the VEGF promoter is important for hypoxia-induced VEGF mRNA expression.

Pastukh V, Roberts JT, Clark DW, Bardwell GC, Patel M, Al-Mehdi AB, Borchert GM, Gillespie MN.

Am J Physiol Lung Cell Mol Physiol. 2015 Dec 1;309(11):L1367-75. doi: 10.1152/ajplung.00236.2015. Epub 2015 Oct 2.

14.

Genome-wide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction.

Ortiz-Barahona A, Villar D, Pescador N, Amigo J, del Peso L.

Nucleic Acids Res. 2010 Apr;38(7):2332-45. doi: 10.1093/nar/gkp1205. Epub 2010 Jan 8.

15.

Pan-genomic binding of hypoxia-inducible transcription factors.

Schödel J, Mole DR, Ratcliffe PJ.

Biol Chem. 2013 Apr;394(4):507-17. doi: 10.1515/hsz-2012-0351. Review.

PMID:
23324384
16.

The hypoxia-inducible transcription factor ZNF395 is controlled by IĸB kinase-signaling and activates genes involved in the innate immune response and cancer.

Jordanovski D, Herwartz C, Pawlowski A, Taute S, Frommolt P, Steger G.

PLoS One. 2013 Sep 23;8(9):e74911. doi: 10.1371/journal.pone.0074911. eCollection 2013.

17.

Characterization of physiologically regulated vectors for the treatment of ischemic disease.

Boast K, Binley K, Iqball S, Price T, Spearman H, Kingsman S, Kingsman A, Naylor S.

Hum Gene Ther. 1999 Sep 1;10(13):2197-208.

PMID:
10498251
18.

A cross-talk between hypoxia and TGF-beta orchestrates erythropoietin gene regulation through SP1 and Smads.

Sánchez-Elsner T, Ramírez JR, Sanz-Rodriguez F, Varela E, Bernabéu C, Botella LM.

J Mol Biol. 2004 Feb 6;336(1):9-24. Erratum in: J Mol Biol. 2004 Mar 19;337(2):499. Rodriguez-Sanz, Francisco [corrected to Sanz-Rodriguez, Francisco].

PMID:
14741200
19.

Cobalt stimulates HIF-1-dependent but inhibits HIF-2-dependent gene expression in liver cancer cells.

Befani C, Mylonis I, Gkotinakou IM, Georgoulias P, Hu CJ, Simos G, Liakos P.

Int J Biochem Cell Biol. 2013 Nov;45(11):2359-68. doi: 10.1016/j.biocel.2013.07.025. Epub 2013 Aug 16.

20.

An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia.

Benita Y, Kikuchi H, Smith AD, Zhang MQ, Chung DC, Xavier RJ.

Nucleic Acids Res. 2009 Aug;37(14):4587-602. doi: 10.1093/nar/gkp425. Epub 2009 Jun 2.

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