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Items: 1 to 20 of 274


Phosphatidylserine-specific phospholipase A1 involved in hepatitis C virus assembly through NS2 complex formation.

Guo M, Pei R, Yang Q, Cao H, Wang Y, Wu C, Chen J, Zhou Y, Hu X, Lu M, Chen X.

J Virol. 2015 Feb;89(4):2367-77. doi: 10.1128/JVI.02982-14. Epub 2014 Dec 10.


NS2 protein of hepatitis C virus interacts with structural and non-structural proteins towards virus assembly.

Popescu CI, Callens N, Trinel D, Roingeard P, Moradpour D, Descamps V, Duverlie G, Penin F, Héliot L, Rouillé Y, Dubuisson J.

PLoS Pathog. 2011 Feb 10;7(2):e1001278. doi: 10.1371/journal.ppat.1001278.


Analysis of hepatitis C virus core/NS5A protein co-localization using novel cell culture systems expressing core-NS2 and NS5A of genotypes 1-7.

Galli A, Scheel TK, Prentoe JC, Mikkelsen LS, Gottwein JM, Bukh J.

J Gen Virol. 2013 Oct;94(Pt 10):2221-35. doi: 10.1099/vir.0.053868-0. Epub 2013 Aug 1.


Detergent-resistant membrane association of NS2 and E2 during hepatitis C virus replication.

Shanmugam S, Saravanabalaji D, Yi M.

J Virol. 2015 Apr;89(8):4562-74. doi: 10.1128/JVI.00123-15. Epub 2015 Feb 11.


Hepatitis C virus NS2 coordinates virus particle assembly through physical interactions with the E1-E2 glycoprotein and NS3-NS4A enzyme complexes.

Stapleford KA, Lindenbach BD.

J Virol. 2011 Feb;85(4):1706-17. doi: 10.1128/JVI.02268-10. Epub 2010 Dec 8.


Cytosolic phospholipase A2 gamma is involved in hepatitis C virus replication and assembly.

Xu S, Pei R, Guo M, Han Q, Lai J, Wang Y, Wu C, Zhou Y, Lu M, Chen X.

J Virol. 2012 Dec;86(23):13025-37. doi: 10.1128/JVI.01785-12. Epub 2012 Sep 26.


Structural and functional studies of nonstructural protein 2 of the hepatitis C virus reveal its key role as organizer of virion assembly.

Jirasko V, Montserret R, Lee JY, Gouttenoire J, Moradpour D, Penin F, Bartenschlager R.

PLoS Pathog. 2010 Dec 16;6(12):e1001233. doi: 10.1371/journal.ppat.1001233.


Trans-complementation of an NS2 defect in a late step in hepatitis C virus (HCV) particle assembly and maturation.

Yi M, Ma Y, Yates J, Lemon SM.

PLoS Pathog. 2009 May;5(5):e1000403. doi: 10.1371/journal.ppat.1000403. Epub 2009 May 1.


Hepatitis C virus NS2 protein serves as a scaffold for virus assembly by interacting with both structural and nonstructural proteins.

Ma Y, Anantpadma M, Timpe JM, Shanmugam S, Singh SM, Lemon SM, Yi M.

J Virol. 2011 Jan;85(1):86-97. doi: 10.1128/JVI.01070-10. Epub 2010 Oct 20.


Signal peptidase complex subunit 1 participates in the assembly of hepatitis C virus through an interaction with E2 and NS2.

Suzuki R, Matsuda M, Watashi K, Aizaki H, Matsuura Y, Wakita T, Suzuki T.

PLoS Pathog. 2013;9(8):e1003589. doi: 10.1371/journal.ppat.1003589. Epub 2013 Aug 29.


Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly.

Appel N, Zayas M, Miller S, Krijnse-Locker J, Schaller T, Friebe P, Kallis S, Engel U, Bartenschlager R.

PLoS Pathog. 2008 Mar 28;4(3):e1000035. doi: 10.1371/journal.ppat.1000035.


Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein.

Vogt DA, Camus G, Herker E, Webster BR, Tsou CL, Greene WC, Yen TS, Ott M.

PLoS Pathog. 2013;9(4):e1003302. doi: 10.1371/journal.ppat.1003302. Epub 2013 Apr 11.


Human Choline Kinase-α Promotes Hepatitis C Virus RNA Replication through Modulation of Membranous Viral Replication Complex Formation.

Wong MT, Chen SS.

J Virol. 2016 Sep 29;90(20):9075-95. doi: 10.1128/JVI.00960-16. Print 2016 Oct 15.


Involvement of hepatitis C virus NS5A hyperphosphorylation mediated by casein kinase I-α in infectious virus production.

Masaki T, Matsunaga S, Takahashi H, Nakashima K, Kimura Y, Ito M, Matsuda M, Murayama A, Kato T, Hirano H, Endo Y, Lemon SM, Wakita T, Sawasaki T, Suzuki T.

J Virol. 2014 Jul;88(13):7541-55. doi: 10.1128/JVI.03170-13. Epub 2014 Apr 23.


Y-Box Binding Protein 1 Stabilizes Hepatitis C Virus NS5A via Phosphorylation-Mediated Interaction with NS5A To Regulate Viral Propagation.

Wang WT, Tsai TY, Chao CH, Lai BY, Wu Lee YH.

J Virol. 2015 Nov;89(22):11584-602. doi: 10.1128/JVI.01513-15. Epub 2015 Sep 9.


Apolipoprotein J, a glucose-upregulated molecular chaperone, stabilizes core and NS5A to promote infectious hepatitis C virus virion production.

Lin CC, Tsai P, Sun HY, Hsu MC, Lee JC, Wu IC, Tsao CW, Chang TT, Young KC.

J Hepatol. 2014 Nov;61(5):984-93. doi: 10.1016/j.jhep.2014.06.026. Epub 2014 Jul 1.


Inhibition of HCV replication by cyclophilin antagonists is linked to replication fitness and occurs by inhibition of membranous web formation.

Madan V, Paul D, Lohmann V, Bartenschlager R.

Gastroenterology. 2014 May;146(5):1361-72.e1-9. doi: 10.1053/j.gastro.2014.01.055. Epub 2014 Jan 31.


Daclatasvir Prevents Hepatitis C Virus Infectivity by Blocking Transfer of the Viral Genome to Assembly Sites.

Boson B, Denolly S, Turlure F, Chamot C, Dreux M, Cosset FL.

Gastroenterology. 2017 Mar;152(4):895-907.e14. doi: 10.1053/j.gastro.2016.11.047. Epub 2016 Dec 5.


Nonstructural 5A Protein of Hepatitis C Virus Regulates Soluble Resistance-Related Calcium-Binding Protein Activity for Viral Propagation.

Tran GV, Luong TT, Park EM, Kim JW, Choi JW, Park C, Lim YS, Hwang SB.

J Virol. 2015 Dec 30;90(6):2794-805. doi: 10.1128/JVI.02493-15.


Vinexin β Interacts with Hepatitis C Virus NS5A, Modulating Its Hyperphosphorylation To Regulate Viral Propagation.

Xiong W, Yang J, Wang M, Wang H, Rao Z, Zhong C, Xin X, Mo L, Yu S, Shen C, Zheng C.

J Virol. 2015 Jul;89(14):7385-400. doi: 10.1128/JVI.00567-15. Epub 2015 May 13.

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