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Items: 1 to 20 of 147

1.

NLRC5 interacts with RIG-I to induce a robust antiviral response against influenza virus infection.

Ranjan P, Singh N, Kumar A, Neerincx A, Kremmer E, Cao W, Davis WG, Katz JM, Gangappa S, Lin R, Kufer TA, Sambhara S.

Eur J Immunol. 2015 Mar;45(3):758-72. doi: 10.1002/eji.201344412. Epub 2014 Dec 23.

2.

Respiratory Syncytial Virus Infection Upregulates NLRC5 and Major Histocompatibility Complex Class I Expression through RIG-I Induction in Airway Epithelial Cells.

Guo X, Liu T, Shi H, Wang J, Ji P, Wang H, Hou Y, Tan RX, Li E.

J Virol. 2015 Aug;89(15):7636-45. doi: 10.1128/JVI.00349-15. Epub 2015 May 13.

3.

Quantitative proteomic analysis of the influenza A virus nonstructural proteins NS1 and NS2 during natural cell infection identifies PACT as an NS1 target protein and antiviral host factor.

Tawaratsumida K, Phan V, Hrincius ER, High AA, Webby R, Redecke V, Häcker H.

J Virol. 2014 Aug;88(16):9038-48. doi: 10.1128/JVI.00830-14. Epub 2014 Jun 4.

4.

Sequence-Specific Modifications Enhance the Broad-Spectrum Antiviral Response Activated by RIG-I Agonists.

Chiang C, Beljanski V, Yin K, Olagnier D, Ben Yebdri F, Steel C, Goulet ML, DeFilippis VR, Streblow DN, Haddad EK, Trautmann L, Ross T, Lin R, Hiscott J.

J Virol. 2015 Aug;89(15):8011-25. doi: 10.1128/JVI.00845-15. Epub 2015 May 27.

5.

Deficiency of the NOD-Like Receptor NLRC5 Results in Decreased CD8+ T Cell Function and Impaired Viral Clearance.

Lupfer CR, Stokes KL, Kuriakose T, Kanneganti TD.

J Virol. 2017 Aug 10;91(17). pii: e00377-17. doi: 10.1128/JVI.00377-17. Print 2017 Sep 1.

6.

Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein.

Rajsbaum R, Albrecht RA, Wang MK, Maharaj NP, Versteeg GA, Nistal-Villán E, García-Sastre A, Gack MU.

PLoS Pathog. 2012;8(11):e1003059. doi: 10.1371/journal.ppat.1003059. Epub 2012 Nov 29.

7.

Influenza A(H1N1)pdm09 virus suppresses RIG-I initiated innate antiviral responses in the human lung.

Wu W, Zhang W, Booth JL, Metcalf JP.

PLoS One. 2012;7(11):e49856. doi: 10.1371/journal.pone.0049856. Epub 2012 Nov 21.

8.

IFN-γ Influences Epithelial Antiviral Responses via Histone Methylation of the RIG-I Promoter.

Spalluto CM, Singhania A, Cellura D, Woelk CH, Sanchez-Elsner T, Staples KJ, Wilkinson TMA.

Am J Respir Cell Mol Biol. 2017 Oct;57(4):428-438. doi: 10.1165/rcmb.2016-0392OC.

PMID:
28481620
9.

Type I IFN triggers RIG-I/TLR3/NLRP3-dependent inflammasome activation in influenza A virus infected cells.

Pothlichet J, Meunier I, Davis BK, Ting JP, Skamene E, von Messling V, Vidal SM.

PLoS Pathog. 2013;9(4):e1003256. doi: 10.1371/journal.ppat.1003256. Epub 2013 Apr 11.

10.

NLRC5 controls basal MHC class I gene expression in an MHC enhanceosome-dependent manner.

Neerincx A, Rodriguez GM, Steimle V, Kufer TA.

J Immunol. 2012 May 15;188(10):4940-50. doi: 10.4049/jimmunol.1103136. Epub 2012 Apr 6.

11.

Phosphatidylinositol-3-kinase (PI3K) is activated by influenza virus vRNA via the pathogen pattern receptor Rig-I to promote efficient type I interferon production.

Hrincius ER, Dierkes R, Anhlan D, Wixler V, Ludwig S, Ehrhardt C.

Cell Microbiol. 2011 Dec;13(12):1907-19. doi: 10.1111/j.1462-5822.2011.01680.x. Epub 2011 Oct 11.

PMID:
21899695
12.

IFNbeta induction by influenza A virus is mediated by RIG-I which is regulated by the viral NS1 protein.

Opitz B, Rejaibi A, Dauber B, Eckhard J, Vinzing M, Schmeck B, Hippenstiel S, Suttorp N, Wolff T.

Cell Microbiol. 2007 Apr;9(4):930-8. Epub 2006 Nov 28.

PMID:
17140406
13.

The NS1 protein of a human influenza virus inhibits type I interferon production and the induction of antiviral responses in primary human dendritic and respiratory epithelial cells.

Haye K, Burmakina S, Moran T, García-Sastre A, Fernandez-Sesma A.

J Virol. 2009 Jul;83(13):6849-62. doi: 10.1128/JVI.02323-08. Epub 2009 Apr 29.

14.

Robust Lys63-Linked Ubiquitination of RIG-I Promotes Cytokine Eruption in Early Influenza B Virus Infection.

Jiang J, Li J, Fan W, Zheng W, Yu M, Chen C, Sun L, Bi Y, Ding C, Gao GF, Liu W.

J Virol. 2016 Jun 24;90(14):6263-6275. doi: 10.1128/JVI.00549-16. Print 2016 Jul 15.

15.

Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses.

Wang Q, Nagarkar DR, Bowman ER, Schneider D, Gosangi B, Lei J, Zhao Y, McHenry CL, Burgens RV, Miller DJ, Sajjan U, Hershenson MB.

J Immunol. 2009 Dec 1;183(11):6989-97. doi: 10.4049/jimmunol.0901386. Epub 2009 Nov 4.

16.

Retinoic acid inducible gene-I and mda-5 are involved in influenza A virus-induced expression of antiviral cytokines.

Sirén J, Imaizumi T, Sarkar D, Pietilä T, Noah DL, Lin R, Hiscott J, Krug RM, Fisher PB, Julkunen I, Matikainen S.

Microbes Infect. 2006 Jul;8(8):2013-20. Epub 2006 May 22.

PMID:
16797201
17.

NS1 protein of influenza A virus inhibits the function of intracytoplasmic pathogen sensor, RIG-I.

Guo Z, Chen LM, Zeng H, Gomez JA, Plowden J, Fujita T, Katz JM, Donis RO, Sambhara S.

Am J Respir Cell Mol Biol. 2007 Mar;36(3):263-9. Epub 2006 Oct 19.

PMID:
17053203
18.

Human primary airway epithelial cells isolated from active smokers have epigenetically impaired antiviral responses.

Wu W, Zhang W, Booth JL, Hutchings DC, Wang X, White VL, Youness H, Cross CD, Zou MH, Burian D, Metcalf JP.

Respir Res. 2016 Sep 7;17(1):111. doi: 10.1186/s12931-016-0428-2.

19.

Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I.

Gack MU, Albrecht RA, Urano T, Inn KS, Huang IC, Carnero E, Farzan M, Inoue S, Jung JU, García-Sastre A.

Cell Host Microbe. 2009 May 8;5(5):439-49. doi: 10.1016/j.chom.2009.04.006.

20.

Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity.

Onomoto K, Jogi M, Yoo JS, Narita R, Morimoto S, Takemura A, Sambhara S, Kawaguchi A, Osari S, Nagata K, Matsumiya T, Namiki H, Yoneyama M, Fujita T.

PLoS One. 2012;7(8):e43031. doi: 10.1371/journal.pone.0043031. Epub 2012 Aug 13. Erratum in: PLoS One. 2012;7(10). doi:10.1371/annotation/dcd836ee-9e23-4538-acb7-450560ba5c1d. PLoS One. 2013;8(4). doi:10.1371/annotation/14a6b875-ed9d-41ae-8ce6-52e8c5c7f85b.

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