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Items: 1 to 20 of 92

1.

Chlamydia infection depends on a functional MDM2-p53 axis.

González E, Rother M, Kerr MC, Al-Zeer MA, Abu-Lubad M, Kessler M, Brinkmann V, Loewer A, Meyer TF.

Nat Commun. 2014 Nov 13;5:5201. doi: 10.1038/ncomms6201.

2.

Tumor suppressor p53 alters host cell metabolism to limit Chlamydia trachomatis infection.

Siegl C, Prusty BK, Karunakaran K, Wischhusen J, Rudel T.

Cell Rep. 2014 Nov 6;9(3):918-29. doi: 10.1016/j.celrep.2014.10.004. Epub 2014 Oct 30.

3.

Chlamydia trachomatis Prevents Apoptosis Via Activation of PDPK1-MYC and Enhanced Mitochondrial Binding of Hexokinase II.

Al-Zeer MA, Xavier A, Abu Lubad M, Sigulla J, Kessler M, Hurwitz R, Meyer TF.

EBioMedicine. 2017 Sep;23:100-110. doi: 10.1016/j.ebiom.2017.08.005. Epub 2017 Aug 5.

4.

Chlamydia inhibit host cell apoptosis by degradation of proapoptotic BH3-only proteins.

Fischer SF, Vier J, Kirschnek S, Klos A, Hess S, Ying S, Häcker G.

J Exp Med. 2004 Oct 4;200(7):905-16. Epub 2004 Sep 27.

5.

Cell death, BAX activation, and HMGB1 release during infection with Chlamydia.

Jungas T, Verbeke P, Darville T, Ojcius DM.

Microbes Infect. 2004 Nov;6(13):1145-55.

PMID:
15488733
6.

A new twist in the feedback loop: stress-activated MDM2 destabilization is required for p53 activation.

Stommel JM, Wahl GM.

Cell Cycle. 2005 Mar;4(3):411-7. Epub 2005 Mar 2. Review.

PMID:
15684615
7.

Premature apoptosis of Chlamydia-infected cells disrupts chlamydial development.

Ying S, Pettengill M, Latham ER, Walch A, Ojcius DM, Häcker G.

J Infect Dis. 2008 Nov 15;198(10):1536-44. doi: 10.1086/592755.

PMID:
18821848
8.

Chlamydia trachomatis plasmid-encoded protein Pgp3 inhibits apoptosis via the PI3K-AKT-mediated MDM2-p53 axis.

Zou Y, Lei W, Su S, Bu J, Zhu S, Huang Q, Li Z.

Mol Cell Biochem. 2018 Aug 21. doi: 10.1007/s11010-018-3422-9. [Epub ahead of print]

PMID:
30132214
9.

Mdm2 affects genome stability independent of p53.

Bouska A, Eischen CM.

Cancer Res. 2009 Mar 1;69(5):1697-701. doi: 10.1158/0008-5472.CAN-08-3732. Epub 2009 Feb 24. Review.

10.

Role of polyamines in p53-dependent apoptosis of intestinal epithelial cells.

Bhattacharya S, Ray RM, Johnson LR.

Cell Signal. 2009 Apr;21(4):509-22. doi: 10.1016/j.cellsig.2008.12.003. Epub 2008 Dec 24.

PMID:
19136059
11.

MDM2 inhibitor MI-319 in combination with cisplatin is an effective treatment for pancreatic cancer independent of p53 function.

Azmi AS, Aboukameel A, Banerjee S, Wang Z, Mohammad M, Wu J, Wang S, Yang D, Philip PA, Sarkar FH, Mohammad RM.

Eur J Cancer. 2010 Apr;46(6):1122-31. doi: 10.1016/j.ejca.2010.01.015. Epub 2010 Feb 13.

12.
13.

Chlamydia inhibit host cell apoptosis by inducing Bag-1 via the MAPK/ERK survival pathway.

Kun D, Xiang-Lin C, Ming Z, Qi L.

Apoptosis. 2013 Sep;18(9):1083-92. doi: 10.1007/s10495-013-0865-z.

PMID:
23708800
14.

Elevated MDM2 boosts the apoptotic activity of p53-MDM2 binding inhibitors by facilitating MDMX degradation.

Xia M, Knezevic D, Tovar C, Huang B, Heimbrook DC, Vassilev LT.

Cell Cycle. 2008 Jun 1;7(11):1604-12. Epub 2008 Mar 17.

PMID:
18520179
15.

EphrinA2 receptor (EphA2) is an invasion and intracellular signaling receptor for Chlamydia trachomatis.

Subbarayal P, Karunakaran K, Winkler AC, Rother M, Gonzalez E, Meyer TF, Rudel T.

PLoS Pathog. 2015 Apr 23;11(4):e1004846. doi: 10.1371/journal.ppat.1004846. eCollection 2015 Apr.

16.
17.

Iron-dependent regulation of MDM2 influences p53 activity and hepatic carcinogenesis.

Dongiovanni P, Fracanzani AL, Cairo G, Megazzini CP, Gatti S, Rametta R, Fargion S, Valenti L.

Am J Pathol. 2010 Feb;176(2):1006-17. doi: 10.2353/ajpath.2010.090249. Epub 2009 Dec 17.

18.

[Abnormal p53-HDM2 interaction in hematological malignancy].

Tabe Y, Kojima K.

Nihon Rinsho. 2014 Jun;72(6):1042-6. Review. Japanese.

PMID:
25016801
19.

In contrast to Chlamydia trachomatis, Waddlia chondrophila grows in human cells without inhibiting apoptosis, fragmenting the Golgi apparatus, or diverting post-Golgi sphingomyelin transport.

Dille S, Kleinschnitz EM, Kontchou CW, Nölke T, Häcker G.

Infect Immun. 2015 Aug;83(8):3268-80. doi: 10.1128/IAI.00322-15. Epub 2015 Jun 8.

20.

Chlamydia cell biology and pathogenesis.

Elwell C, Mirrashidi K, Engel J.

Nat Rev Microbiol. 2016 Jun;14(6):385-400. doi: 10.1038/nrmicro.2016.30. Epub 2016 Apr 25. Review.

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