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Items: 1 to 20 of 112

1.

ChREBP, a glucose-responsive transcriptional factor, enhances glucose metabolism to support biosynthesis in human cytomegalovirus-infected cells.

Yu Y, Maguire TG, Alwine JC.

Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):1951-6. doi: 10.1073/pnas.1310779111. Epub 2014 Jan 21.

2.

PKR-like endoplasmic reticulum kinase is necessary for lipogenic activation during HCMV infection.

Yu Y, Pierciey FJ Jr, Maguire TG, Alwine JC.

PLoS Pathog. 2013;9(4):e1003266. doi: 10.1371/journal.ppat.1003266. Epub 2013 Apr 4.

3.

A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism.

Herman MA, Peroni OD, Villoria J, Schön MR, Abumrad NA, Blüher M, Klein S, Kahn BB.

Nature. 2012 Apr 19;484(7394):333-8. doi: 10.1038/nature10986.

4.

Identification of HNF-4α as a key transcription factor to promote ChREBP expression in response to glucose.

Meng J, Feng M, Dong W, Zhu Y, Li Y, Zhang P, Wu L, Li M, Lu Y, Chen H, Liu X, Lu Y, Sun H, Tong X.

Sci Rep. 2016 Mar 31;6:23944. doi: 10.1038/srep23944.

5.

Integrated expression profiling and genome-wide analysis of ChREBP targets reveals the dual role for ChREBP in glucose-regulated gene expression.

Jeong YS, Kim D, Lee YS, Kim HJ, Han JY, Im SS, Chong HK, Kwon JK, Cho YH, Kim WK, Osborne TF, Horton JD, Jun HS, Ahn YH, Ahn SM, Cha JY.

PLoS One. 2011;6(7):e22544. doi: 10.1371/journal.pone.0022544. Epub 2011 Jul 21.

6.

ChREBP regulates fructose-induced glucose production independently of insulin signaling.

Kim MS, Krawczyk SA, Doridot L, Fowler AJ, Wang JX, Trauger SA, Noh HL, Kang HJ, Meissen JK, Blatnik M, Kim JK, Lai M, Herman MA.

J Clin Invest. 2016 Nov 1;126(11):4372-4386. doi: 10.1172/JCI81993. Epub 2016 Sep 26.

7.

Human cytomegalovirus infection induces adipocyte-like lipogenesis through activation of sterol regulatory element binding protein 1.

Yu Y, Maguire TG, Alwine JC.

J Virol. 2012 Mar;86(6):2942-9. doi: 10.1128/JVI.06467-11. Epub 2012 Jan 18.

8.

ChREBP and LXRα mediate synergistically lipogenesis induced by glucose in porcine adipocytes.

Zhang GH, Lu JX, Chen Y, Guo PH, Qiao ZL, Feng RF, Chen SE, Bai JL, Huo SD, Ma ZR.

Gene. 2015 Jul 1;565(1):30-8. doi: 10.1016/j.gene.2015.03.057. Epub 2015 Mar 28.

PMID:
25827716
9.

ChREBP: a glucose-activated transcription factor involved in the development of metabolic syndrome.

Iizuka K, Horikawa Y.

Endocr J. 2008 Aug;55(4):617-24. Epub 2008 May 19. Review.

10.

High glucose-induced O-GlcNAcylated carbohydrate response element-binding protein (ChREBP) mediates mesangial cell lipogenesis and fibrosis: the possible role in the development of diabetic nephropathy.

Park MJ, Kim DI, Lim SK, Choi JH, Han HJ, Yoon KC, Park SH.

J Biol Chem. 2014 May 9;289(19):13519-30. doi: 10.1074/jbc.M113.530139. Epub 2014 Mar 10.

11.

The glucose-responsive transcription factor ChREBP contributes to glucose-dependent anabolic synthesis and cell proliferation.

Tong X, Zhao F, Mancuso A, Gruber JJ, Thompson CB.

Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21660-5. doi: 10.1073/pnas.0911316106. Epub 2009 Dec 7.

12.
13.

Flightless I homolog negatively regulates ChREBP activity in cancer cells.

Wu L, Chen H, Zhu Y, Meng J, Li Y, Li M, Yang D, Zhang P, Feng M, Tong X.

Int J Biochem Cell Biol. 2013 Nov;45(11):2688-97. doi: 10.1016/j.biocel.2013.09.004. Epub 2013 Sep 17.

PMID:
24055811
14.

Krüppel-like factor-10 is directly regulated by carbohydrate response element-binding protein in rat primary hepatocytes.

Iizuka K, Takeda J, Horikawa Y.

Biochem Biophys Res Commun. 2011 Sep 9;412(4):638-43. doi: 10.1016/j.bbrc.2011.08.016. Epub 2011 Aug 11.

PMID:
21856285
15.

Importin-alpha protein binding to a nuclear localization signal of carbohydrate response element-binding protein (ChREBP).

Ge Q, Nakagawa T, Wynn RM, Chook YM, Miller BC, Uyeda K.

J Biol Chem. 2011 Aug 12;286(32):28119-27. doi: 10.1074/jbc.M111.237016. Epub 2011 Jun 10.

16.

ChREBP mediates glucose repression of peroxisome proliferator-activated receptor alpha expression in pancreatic beta-cells.

Boergesen M, Poulsen Ll, Schmidt SF, Frigerio F, Maechler P, Mandrup S.

J Biol Chem. 2011 Apr 15;286(15):13214-25. doi: 10.1074/jbc.M110.215467. Epub 2011 Jan 31.

17.

Regulation of nuclear import/export of carbohydrate response element-binding protein (ChREBP): interaction of an alpha-helix of ChREBP with the 14-3-3 proteins and regulation by phosphorylation.

Sakiyama H, Wynn RM, Lee WR, Fukasawa M, Mizuguchi H, Gardner KH, Repa JJ, Uyeda K.

J Biol Chem. 2008 Sep 5;283(36):24899-908. doi: 10.1074/jbc.M804308200. Epub 2008 Jul 7.

18.

Islet ChREBP-β is increased in diabetes and controls ChREBP-α and glucose-induced gene expression via a negative feedback loop.

Jing G, Chen J, Xu G, Shalev A.

Mol Metab. 2016 Sep 30;5(12):1208-1215. doi: 10.1016/j.molmet.2016.09.010. eCollection 2016 Dec.

19.

Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity.

Bindesbøll C, Fan Q, Nørgaard RC, MacPherson L, Ruan HB, Wu J, Pedersen TÅ, Steffensen KR, Yang X, Matthews J, Mandrup S, Nebb HI, Grønning-Wang LM.

J Lipid Res. 2015 Apr;56(4):771-85. doi: 10.1194/jlr.M049130. Epub 2015 Feb 27.

20.

A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism.

Fisher FM, Kim M, Doridot L, Cunniff JC, Parker TS, Levine DM, Hellerstein MK, Hudgins LC, Maratos-Flier E, Herman MA.

Mol Metab. 2016 Nov 23;6(1):14-21. doi: 10.1016/j.molmet.2016.11.008. eCollection 2017 Jan.

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