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Items: 1 to 20 of 219

1.

Activity of hexokinase is increased by its interaction with hepatitis C virus protein NS5A.

Ramière C, Rodriguez J, Enache LS, Lotteau V, André P, Diaz O.

J Virol. 2014 Mar;88(6):3246-54. doi: 10.1128/JVI.02862-13. Epub 2014 Jan 3.

2.

Hepatitis C virus NS5A protein interacts with phosphatidylinositol 4-kinase type IIIalpha and regulates viral propagation.

Lim YS, Hwang SB.

J Biol Chem. 2011 Apr 1;286(13):11290-8. doi: 10.1074/jbc.M110.194472. Epub 2011 Feb 5.

3.

Role for TBC1D20 and Rab1 in hepatitis C virus replication via interaction with lipid droplet-bound nonstructural protein 5A.

Nevo-Yassaf I, Yaffe Y, Asher M, Ravid O, Eizenberg S, Henis YI, Nahmias Y, Hirschberg K, Sklan EH.

J Virol. 2012 Jun;86(12):6491-502. doi: 10.1128/JVI.00496-12. Epub 2012 Apr 4.

4.

Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein.

Vogt DA, Camus G, Herker E, Webster BR, Tsou CL, Greene WC, Yen TS, Ott M.

PLoS Pathog. 2013;9(4):e1003302. doi: 10.1371/journal.ppat.1003302. Epub 2013 Apr 11.

5.

Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation.

George A, Panda S, Kudmulwar D, Chhatbar SP, Nayak SC, Krishnan HH.

J Biol Chem. 2012 Feb 10;287(7):5042-58. doi: 10.1074/jbc.M111.308916. Epub 2011 Dec 19.

6.

Regulation of hepatitis C virus replication by nuclear translocation of nonstructural 5A protein and transcriptional activation of host genes.

Maqbool MA, Imache MR, Higgs MR, Carmouse S, Pawlotsky JM, Lerat H.

J Virol. 2013 May;87(10):5523-39. doi: 10.1128/JVI.00585-12. Epub 2013 Mar 6. Erratum in: J Virol. 2013 Sep;87(17):9963.

7.

Hepatitis C virus NS5B and host cyclophilin A share a common binding site on NS5A.

Rosnoblet C, Fritzinger B, Legrand D, Launay H, Wieruszeski JM, Lippens G, Hanoulle X.

J Biol Chem. 2012 Dec 28;287(53):44249-60. doi: 10.1074/jbc.M112.392209. Epub 2012 Nov 14.

8.

Viperin inhibits hepatitis C virus replication by interfering with binding of NS5A to host protein hVAP-33.

Wang S, Wu X, Pan T, Song W, Wang Y, Zhang F, Yuan Z.

J Gen Virol. 2012 Jan;93(Pt 1):83-92. doi: 10.1099/vir.0.033860-0. Epub 2011 Sep 28.

PMID:
21957124
9.

1Hepatitis C virus NS5A protein modulates c-Jun N-terminal kinase through interaction with tumor necrosis factor receptor-associated factor 2.

Park KJ, Choi SH, Choi DH, Park JM, Yie SW, Lee SY, Hwang SB.

J Biol Chem. 2003 Aug 15;278(33):30711-8. Epub 2003 Jun 7.

10.

Hepatitis C virus NS5A protein enhances gluconeogenesis through upregulation of Akt-/JNK-PEPCK signalling pathways.

Kuo YC, Chen IY, Chang SC, Wu SC, Hung TM, Lee PH, Shimotohno K, Chang MF.

Liver Int. 2014 Oct;34(9):1358-68.

PMID:
25360475
11.

Nonstructural 5A protein of hepatitis C virus interacts with pyruvate carboxylase and modulates viral propagation.

Yim SA, Lim YS, Kim JW, Hwang SB.

PLoS One. 2013 Jul 4;8(7):e68170. doi: 10.1371/journal.pone.0068170. Print 2013.

12.

Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B.

Hamamoto I, Nishimura Y, Okamoto T, Aizaki H, Liu M, Mori Y, Abe T, Suzuki T, Lai MM, Miyamura T, Moriishi K, Matsuura Y.

J Virol. 2005 Nov;79(21):13473-82.

13.

HCV NS5A co-operates with PKR in modulating HCV IRES-dependent translation.

Karamichali E, Foka P, Tsitoura E, Kalliampakou K, Kazazi D, Karayiannis P, Georgopoulou U, Mavromara P.

Infect Genet Evol. 2014 Aug;26:113-22. doi: 10.1016/j.meegid.2014.04.015. Epub 2014 May 9.

PMID:
24815730
14.

The Hepatitis C virus NS5A protein activates a phosphoinositide 3-kinase-dependent survival signaling cascade.

Street A, Macdonald A, Crowder K, Harris M.

J Biol Chem. 2004 Mar 26;279(13):12232-41. Epub 2004 Jan 5.

15.

Hepatitis C virus replication is modulated by the interaction of nonstructural protein NS5B and fatty acid synthase.

Huang JT, Tseng CP, Liao MH, Lu SC, Yeh WZ, Sakamoto N, Chen CM, Cheng JC.

J Virol. 2013 May;87(9):4994-5004. doi: 10.1128/JVI.02526-12. Epub 2013 Feb 20.

16.

Hepatitis C virus NS5A protein interacts with lysine methyltransferase SET and MYND domain-containing 3 and induces activator protein 1 activation.

Chen M, Gan X, Yoshino K, Kitakawa M, Shoji I, Deng L, Hotta H.

Microbiol Immunol. 2016 Jun;60(6):407-17. doi: 10.1111/1348-0421.12383.

17.

The FUSE binding protein is a cellular factor required for efficient replication of hepatitis C virus.

Zhang Z, Harris D, Pandey VN.

J Virol. 2008 Jun;82(12):5761-73. doi: 10.1128/JVI.00064-08. Epub 2008 Apr 9.

18.

Apolipoprotein J, a glucose-upregulated molecular chaperone, stabilizes core and NS5A to promote infectious hepatitis C virus virion production.

Lin CC, Tsai P, Sun HY, Hsu MC, Lee JC, Wu IC, Tsao CW, Chang TT, Young KC.

J Hepatol. 2014 Nov;61(5):984-93. doi: 10.1016/j.jhep.2014.06.026. Epub 2014 Jul 1.

PMID:
24996046
19.

Daclatasvir inhibits hepatitis C virus NS5A motility and hyper-accumulation of phosphoinositides.

Chukkapalli V, Berger KL, Kelly SM, Thomas M, Deiters A, Randall G.

Virology. 2015 Feb;476:168-179. doi: 10.1016/j.virol.2014.12.018. Epub 2014 Dec 26.

20.

Inhibition of HCV replication by oxysterol-binding protein-related protein 4 (ORP4) through interaction with HCV NS5B and alteration of lipid droplet formation.

Park IW, Ndjomou J, Wen Y, Liu Z, Ridgway ND, Kao CC, He JJ.

PLoS One. 2013 Sep 17;8(9):e75648. doi: 10.1371/journal.pone.0075648. eCollection 2013.

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