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Items: 1 to 20 of 67

1.

The cyclin-dependent kinase ortholog pUL97 of human cytomegalovirus interacts with cyclins.

Graf L, Webel R, Wagner S, Hamilton ST, Rawlinson WD, Sticht H, Marschall M.

Viruses. 2013 Dec 18;5(12):3213-30. doi: 10.3390/v5123213.

2.

The Interaction between Cyclin B1 and Cytomegalovirus Protein Kinase pUL97 is Determined by an Active Kinase Domain.

Steingruber M, Socher E, Hutterer C, Webel R, Bergbrede T, Lenac T, Sticht H, Marschall M.

Viruses. 2015 Aug 11;7(8):4582-601. doi: 10.3390/v7082834.

3.

Proteomic Interaction Patterns between Human Cyclins, the Cyclin-Dependent Kinase Ortholog pUL97 and Additional Cytomegalovirus Proteins.

Steingruber M, Kraut A, Socher E, Sticht H, Reichel A, Stamminger T, Amin B, Couté Y, Hutterer C, Marschall M.

Viruses. 2016 Aug 18;8(8). pii: E219. doi: 10.3390/v8080219.

4.

Recruitment of cyclin-dependent kinase 9 to nuclear compartments during cytomegalovirus late replication: importance of an interaction between viral pUL69 and cyclin T1.

Feichtinger S, Stamminger T, Müller R, Graf L, Klebl B, Eickhoff J, Marschall M.

J Gen Virol. 2011 Jul;92(Pt 7):1519-31. doi: 10.1099/vir.0.030494-0. Epub 2011 Mar 30.

PMID:
21450947
5.

Regulatory roles of protein kinases in cytomegalovirus replication.

Marschall M, Feichtinger S, Milbradt J.

Adv Virus Res. 2011;80:69-101. doi: 10.1016/B978-0-12-385987-7.00004-X. Review.

PMID:
21762822
6.

New insight into the phosphorylation-regulated intranuclear localization of human cytomegalovirus pUL69 mediated by cyclin-dependent kinases (CDKs) and viral CDK orthologue pUL97.

Graf L, Feichtinger S, Naing Z, Hutterer C, Milbradt J, Webel R, Wagner S, Scott GM, Hamilton ST, Rawlinson WD, Stamminger T, Thomas M, Marschall M.

J Gen Virol. 2016 Jan;97(1):144-51. doi: 10.1099/jgv.0.000337. Epub 2015 Nov 6.

PMID:
26555090
7.

Cyclin-dependent Kinases Phosphorylate the Cytomegalovirus RNA Export Protein pUL69 and Modulate Its Nuclear Localization and Activity.

Rechter S, Scott GM, Eickhoff J, Zielke K, Auerochs S, Müller R, Stamminger T, Rawlinson WD, Marschall M.

J Biol Chem. 2009 Mar 27;284(13):8605-13. doi: 10.1074/jbc.M805693200. Epub 2009 Jan 29.

8.

Mapping of a self-interaction domain of the cytomegalovirus protein kinase pUL97.

Schregel V, Auerochs S, Jochmann R, Maurer K, Stamminger T, Marschall M.

J Gen Virol. 2007 Feb;88(Pt 2):395-404.

PMID:
17251555
9.

The protein kinase pUL97 of human cytomegalovirus interacts with and phosphorylates the DNA polymerase processivity factor pUL44.

Marschall M, Freitag M, Suchy P, Romaker D, Kupfer R, Hanke M, Stamminger T.

Virology. 2003 Jun 20;311(1):60-71.

10.

Cytomegaloviral protein kinase pUL97 interacts with the nuclear mRNA export factor pUL69 to modulate its intranuclear localization and activity.

Thomas M, Rechter S, Milbradt J, Auerochs S, Müller R, Stamminger T, Marschall M.

J Gen Virol. 2009 Mar;90(Pt 3):567-78. doi: 10.1099/vir.0.005827-0.

PMID:
19218201
11.

Human cytomegalovirus tegument protein pp150 acts as a cyclin A2-CDK-dependent sensor of the host cell cycle and differentiation state.

Bogdanow B, Weisbach H, von Einem J, Straschewski S, Voigt S, Winkler M, Hagemeier C, Wiebusch L.

Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17510-5. doi: 10.1073/pnas.1312235110. Epub 2013 Oct 7.

12.

Two isoforms of the protein kinase pUL97 of human cytomegalovirus are differentially regulated in their nuclear translocation.

Webel R, Milbradt J, Auerochs S, Schregel V, Held C, Nöbauer K, Razzazi-Fazeli E, Jardin C, Wittenberg T, Sticht H, Marschall M.

J Gen Virol. 2011 Mar;92(Pt 3):638-49. doi: 10.1099/vir.0.026799-0. Epub 2010 Nov 17.

PMID:
21084499
13.

Antagonistic Relationship between Human Cytomegalovirus pUL27 and pUL97 Activities during Infection.

Bigley TM, Reitsma JM, Terhune SS.

J Virol. 2015 Oct;89(20):10230-46. doi: 10.1128/JVI.00986-15. Epub 2015 Jul 29.

14.

The human cytomegalovirus UL97 protein is phosphorylated and a component of virions.

van Zeijl M, Fairhurst J, Baum EZ, Sun L, Jones TR.

Virology. 1997 Apr 28;231(1):72-80.

15.

Inhibitors of human cytomegalovirus replication drastically reduce the activity of the viral protein kinase pUL97.

Marschall M, Stein-Gerlach M, Freitag M, Kupfer R, van Den Bogaard M, Stamminger T.

J Gen Virol. 2001 Jun;82(Pt 6):1439-50.

PMID:
11369889
16.

Analysis of the structure-activity relationship of four herpesviral UL97 subfamily protein kinases reveals partial but not full functional conservation.

Romaker D, Schregel V, Maurer K, Auerochs S, Marzi A, Sticht H, Marschall M.

J Med Chem. 2006 Nov 30;49(24):7044-53.

PMID:
17125257
17.

Human cytomegalovirus pUL97 kinase induces global changes in the infected cell phosphoproteome.

Oberstein A, Perlman DH, Shenk T, Terry LJ.

Proteomics. 2015 Jun;15(12):2006-22. doi: 10.1002/pmic.201400607. Epub 2015 May 12.

18.

Nuclear import of isoforms of the cytomegalovirus kinase pUL97 is mediated by differential activity of NLS1 and NLS2 both acting through classical importin-α binding.

Webel R, Solbak SM, Held C, Milbradt J, Groß A, Eichler J, Wittenberg T, Jardin C, Sticht H, Fossen T, Marschall M.

J Gen Virol. 2012 Aug;93(Pt 8):1756-68. doi: 10.1099/vir.0.040592-0. Epub 2012 May 2.

PMID:
22552943
19.

Differential properties of cytomegalovirus pUL97 kinase isoforms affect viral replication and maribavir susceptibility.

Webel R, Hakki M, Prichard MN, Rawlinson WD, Marschall M, Chou S.

J Virol. 2014 May;88(9):4776-85. doi: 10.1128/JVI.00192-14. Epub 2014 Feb 12.

20.

Identification of inhibitors for a virally encoded protein kinase by 2 different screening systems: in vitro kinase assay and in-cell activity assay.

Mett H, Hölscher K, Degen H, Esdar C, De Neumann BF, Flicke B, Freudenreich T, Holzer G, Schinzel S, Stamminger T, Stein-Gerlach M, Marschall M, Herget T.

J Biomol Screen. 2005 Feb;10(1):36-45.

PMID:
15695342

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