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Items: 1 to 20 of 102


A gene signature of bone metastatic colonization sensitizes for tumor-induced osteolysis and predicts survival in lung cancer.

Luis-Ravelo D, Antón I, Zandueta C, Valencia K, Ormazábal C, Martínez-Canarias S, Guruceaga E, Perurena N, Vicent S, De Las Rivas J, Lecanda F.

Oncogene. 2014 Oct 23;33(43):5090-9. doi: 10.1038/onc.2013.440. Epub 2013 Oct 28.


A novel lung cancer signature mediates metastatic bone colonization by a dual mechanism.

Vicent S, Luis-Ravelo D, Antón I, García-Tuñón I, Borrás-Cuesta F, Dotor J, De Las Rivas J, Lecanda F.

Cancer Res. 2008 Apr 1;68(7):2275-85. doi: 10.1158/0008-5472.CAN-07-6493.


miRNA cargo within exosome-like vesicle transfer influences metastatic bone colonization.

Valencia K, Luis-Ravelo D, Bovy N, Antón I, Martínez-Canarias S, Zandueta C, Ormazábal C, Struman I, Tabruyn S, Rebmann V, De Las Rivas J, Guruceaga E, Bandrés E, Lecanda F.

Mol Oncol. 2014 May;8(3):689-703. doi: 10.1016/j.molonc.2014.01.012. Epub 2014 Feb 6.


Inhibition of collagen receptor discoidin domain receptor-1 (DDR1) reduces cell survival, homing, and colonization in lung cancer bone metastasis.

Valencia K, Ormazábal C, Zandueta C, Luis-Ravelo D, Antón I, Pajares MJ, Agorreta J, Montuenga LM, Martínez-Canarias S, Leitinger B, Lecanda F.

Clin Cancer Res. 2012 Feb 15;18(4):969-80. doi: 10.1158/1078-0432.CCR-11-1686. Epub 2012 Jan 5.


RHOB influences lung adenocarcinoma metastasis and resistance in a host-sensitive manner.

Luis-Ravelo D, Antón I, Zandueta C, Valencia K, Pajares MJ, Agorreta J, Montuenga L, Vicent S, Wistuba II, De Las Rivas J, Lecanda F.

Mol Oncol. 2014 Mar;8(2):196-206. doi: 10.1016/j.molonc.2013.11.001. Epub 2013 Nov 12.


Tumor-derived interleukin-8 stimulates osteolysis independent of the receptor activator of nuclear factor-kappaB ligand pathway.

Bendre MS, Margulies AG, Walser B, Akel NS, Bhattacharrya S, Skinner RA, Swain F, Ramani V, Mohammad KS, Wessner LL, Martinez A, Guise TA, Chirgwin JM, Gaddy D, Suva LJ.

Cancer Res. 2005 Dec 1;65(23):11001-9.


A cross-species analysis of a mouse model of breast cancer-specific osteolysis and human bone metastases using gene expression profiling.

Sadanandam A, Futakuchi M, Lyssiotis CA, Gibb WJ, Singh RK.

BMC Cancer. 2011 Jul 20;11:304. doi: 10.1186/1471-2407-11-304.


Matrix metalloproteinase (MMP)-13 regulates mammary tumor-induced osteolysis by activating MMP9 and transforming growth factor-beta signaling at the tumor-bone interface.

Nannuru KC, Futakuchi M, Varney ML, Vincent TM, Marcusson EG, Singh RK.

Cancer Res. 2010 May 1;70(9):3494-504. doi: 10.1158/0008-5472.CAN-09-3251. Epub 2010 Apr 20.


Tumor-stromal interactions of the bone microenvironment: in vitro findings and potential in vivo relevance in metastatic lung cancer models.

Luis-Ravelo D, Antón I, Vicent S, Hernández I, Valencia K, Zandueta C, Martínez-Canarias S, Gúrpide A, Lecanda F.

Clin Exp Metastasis. 2011 Dec;28(8):779-91. doi: 10.1007/s10585-011-9409-5. Epub 2011 Jul 28.


[Establishment of a novel chinese human lung adenocarcinoma cell line CPA-Yang3 and its real bone metastasis clone CPA-Yang3BM in immunodeficient mice].

Yang S, Shi M, Cao J, Su J, Zhao L, Lei B, Chang C, Lu J, Ye J, Xie W.

Zhongguo Fei Ai Za Zhi. 2011 Feb;14(2):79-85. doi: 10.3779/j.issn.1009-3419.2011.02.01. Chinese.


Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions.

Akech J, Wixted JJ, Bedard K, van der Deen M, Hussain S, Guise TA, van Wijnen AJ, Stein JL, Languino LR, Altieri DC, Pratap J, Keller E, Stein GS, Lian JB.

Oncogene. 2010 Feb 11;29(6):811-21. doi: 10.1038/onc.2009.389. Epub 2009 Nov 16.


Matrix rigidity induces osteolytic gene expression of metastatic breast cancer cells.

Ruppender NS, Merkel AR, Martin TJ, Mundy GR, Sterling JA, Guelcher SA.

PLoS One. 2010 Nov 15;5(11):e15451. doi: 10.1371/journal.pone.0015451.


Wnt signaling induces gene expression of factors associated with bone destruction in lung and breast cancer.

Johnson RW, Merkel AR, Page JM, Ruppender NS, Guelcher SA, Sterling JA.

Clin Exp Metastasis. 2014 Dec;31(8):945-59. doi: 10.1007/s10585-014-9682-1. Epub 2014 Oct 31.


Colony-stimulating factor 1 potentiates lung cancer bone metastasis.

Hung JY, Horn D, Woodruff K, Prihoda T, LeSaux C, Peters J, Tio F, Abboud-Werner SL.

Lab Invest. 2014 Apr;94(4):371-81. doi: 10.1038/labinvest.2014.1. Epub 2014 Jan 27.


Pathogenic role of connective tissue growth factor (CTGF/CCN2) in osteolytic metastasis of breast cancer.

Shimo T, Kubota S, Yoshioka N, Ibaragi S, Isowa S, Eguchi T, Sasaki A, Takigawa M.

J Bone Miner Res. 2006 Jul;21(7):1045-59.


MicroRNA-33a functions as a bone metastasis suppressor in lung cancer by targeting parathyroid hormone related protein.

Kuo PL, Liao SH, Hung JY, Huang MS, Hsu YL.

Biochim Biophys Acta. 2013 Jun;1830(6):3756-66. doi: 10.1016/j.bbagen.2013.02.022. Epub 2013 Mar 1.


[Establishing the nude mice bone metastasis model of lung adenocarcinoma and applying MicroCT into the observation].

Cui Y, Geng Q, Gu A, Zhu M, Kong H, Sun L, Liu L, Yan M, Yao M.

Zhongguo Fei Ai Za Zhi. 2013 Sep;16(9):452-9. doi: 10.3779/j.issn.1009-3419.2013.09.03. Chinese.


Novel alternatively spliced ADAM8 isoforms contribute to the aggressive bone metastatic phenotype of lung cancer.

Hernández I, Moreno JL, Zandueta C, Montuenga L, Lecanda F.

Oncogene. 2010 Jul 1;29(26):3758-69. doi: 10.1038/onc.2010.130. Epub 2010 May 10.


E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex.

von Burstin J, Eser S, Paul MC, Seidler B, Brandl M, Messer M, von Werder A, Schmidt A, Mages J, Pagel P, Schnieke A, Schmid RM, Schneider G, Saur D.

Gastroenterology. 2009 Jul;137(1):361-71, 371.e1-5. doi: 10.1053/j.gastro.2009.04.004. Epub 2009 Apr 9.


miR-335 inhibits small cell lung cancer bone metastases via IGF-IR and RANKL pathways.

Gong M, Ma J, Guillemette R, Zhou M, Yang Y, Yang Y, Hock JM, Yu X.

Mol Cancer Res. 2014 Jan;12(1):101-10. doi: 10.1158/1541-7786.MCR-13-0136. Epub 2013 Aug 21.

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