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Association between dopamine D4 receptor polymorphism and age related changes in brain glucose metabolism.

Volkow ND, Tomasi D, Wang GJ, Telang F, Fowler JS, Goldstein RZ, Klein N, Wong C, Swanson JM, Shumay E.

PLoS One. 2013 May 22;8(5):e63492. doi: 10.1371/journal.pone.0063492. Print 2013.


Increased brain activity to unpleasant stimuli in individuals with the 7R allele of the DRD4 gene.

Gehricke JG, Swanson JM, Duong S, Nguyen J, Wigal TL, Fallon J, Caburian C, Muftuler LT, Moyzis RK.

Psychiatry Res. 2015 Jan 30;231(1):58-63. doi: 10.1016/j.pscychresns.2014.10.021. Epub 2014 Nov 4.


Neural correlates of inhibitory control and functional genetic variation in the dopamine D4 receptor gene.

Mulligan RC, Kristjansson SD, Reiersen AM, Parra AS, Anokhin AP.

Neuropsychologia. 2014 Sep;62:306-18. doi: 10.1016/j.neuropsychologia.2014.07.033. Epub 2014 Aug 5.


18F-fluorodeoxyglucose positron emission tomography, aging, and apolipoprotein E genotype in cognitively normal persons.

Knopman DS, Jack CR Jr, Wiste HJ, Lundt ES, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Roberts RO, Boeve BF, Petersen RC.

Neurobiol Aging. 2014 Sep;35(9):2096-106. doi: 10.1016/j.neurobiolaging.2014.03.006. Epub 2014 Mar 11.


Novelty seeking and the dopamine D4 receptor gene (DRD4) revisited in Asians: haplotype characterization and relevance of the 2-repeat allele.

Reist C, Ozdemir V, Wang E, Hashemzadeh M, Mee S, Moyzis R.

Am J Med Genet B Neuropsychiatr Genet. 2007 Jun 5;144B(4):453-7.


Effect of model choice in genetic association studies: DRD4 exon III VNTR and cigarette use in young adults.

Das D, Tan X, Easteal S.

Am J Med Genet B Neuropsychiatr Genet. 2011 Apr;156B(3):346-51. doi: 10.1002/ajmg.b.31169. Epub 2011 Jan 13.


The genetic architecture of selection at the human dopamine receptor D4 (DRD4) gene locus.

Wang E, Ding YC, Flodman P, Kidd JR, Kidd KK, Grady DL, Ryder OA, Spence MA, Swanson JM, Moyzis RK.

Am J Hum Genet. 2004 May;74(5):931-44. Epub 2004 Apr 9.


Dopamine D4 receptors modulate brain metabolic activity in the prefrontal cortex and cerebellum at rest and in response to methylphenidate.

Michaelides M, Pascau J, Gispert JD, Delis F, Grandy DK, Wang GJ, Desco M, Rubinstein M, Volkow ND, Thanos PK.

Eur J Neurosci. 2010 Aug;32(4):668-76. doi: 10.1111/j.1460-9568.2010.07319.x. Epub 2010 Jul 16.


The association of exon 3 VNTR polymorphism of the dopamine receptor D4 (DRD4) gene with alcoholism in Mexican Americans.

Du Y, Yang M, Yeh HW, Wan YJ.

Psychiatry Res. 2010 May 30;177(3):358-60. doi: 10.1016/j.psychres.2010.02.021. Epub 2010 Apr 1.


Dopamine D4 receptor exon III alleles and variation of novelty seeking in alcoholics.

Sander T, Harms H, Dufeu P, Kuhn S, Rommelspacher H, Schmidt LG.

Am J Med Genet. 1997 Sep 19;74(5):483-7.


Association of VNTR polymorphisms in the MAOA promoter and DRD4 exon 3 with heroin dependence in male Chinese addicts.

Chien CC, Lin CH, Chang YY, Lung FW.

World J Biol Psychiatry. 2010 Mar;11(2 Pt 2):409-16. doi: 10.3109/15622970903304459.


A role for the DRD4 exon III VNTR in modifying the association between nicotine dependence and neuroticism.

Ellis JA, Olsson CA, Moore E, Greenwood P, Van De Ven MO, Patton GC.

Nicotine Tob Res. 2011 Feb;13(2):64-9. doi: 10.1093/ntr/ntq210. Epub 2010 Dec 2.


D4 dopamine-receptor (DRD4) alleles and novelty seeking in substance-dependent, personality-disorder, and control subjects.

Gelernter J, Kranzler H, Coccaro E, Siever L, New A, Mulgrew CL.

Am J Hum Genet. 1997 Nov;61(5):1144-52.


Association between the seven-repeat allele of the dopamine-4 receptor gene (DRD4) and spontaneous food intake in pre-school children.

Silveira PP, Portella AK, Kennedy JL, Gaudreau H, Davis C, Steiner M, Soares CN, Matthews SG, Sokolowski MB, Dubé L, Loucks EB, Hamilton J, Meaney MJ, Levitan RD; MAVAN Study Team.

Appetite. 2014 Feb;73:15-22. doi: 10.1016/j.appet.2013.10.004. Epub 2013 Oct 20.


Is there a role for rare variants in DRD4 gene in the susceptibility for ADHD? Searching for an effect of allelic heterogeneity.

Tovo-Rodrigues L, Rohde LA, Roman T, Schmitz M, Polanczyk G, Zeni C, Marques FZ, Contini V, Grevet EH, Belmonte-de-Abreu P, Bau CH, Hutz MH.

Mol Psychiatry. 2012 May;17(5):520-6. doi: 10.1038/mp.2011.12. Epub 2011 Mar 15.


A DRD4/BDNF gene-gene interaction associated with maximum BMI in women with bulimia nervosa.

Kaplan AS, Levitan RD, Yilmaz Z, Davis C, Tharmalingam S, Kennedy JL.

Int J Eat Disord. 2008 Jan;41(1):22-8.


The dopamine D Receptor (DRD4) gene exon III polymorphism, problematic alcohol use and novelty seeking: direct and mediated genetic effects.

Ray LA, Bryan A, Mackillop J, McGeary J, Hesterberg K, Hutchison KE.

Addict Biol. 2009 Apr;14(2):238-44. doi: 10.1111/j.1369-1600.2008.00120.x. Epub 2008 Aug 19.


Exon 3 polymorphisms of dopamine D4 receptor (DRD4) gene and attention deficit hyperactivity disorder in Chinese children.

Cheuk DK, Li SY, Wong V.

Am J Med Genet B Neuropsychiatr Genet. 2006 Dec 5;141B(8):907-11.


Cognitive and emotional processing associated with the Season of Birth and dopamine D4 receptor gene.

Roussos P, Giakoumaki SG, Bitsios P.

Neuropsychologia. 2010 Nov;48(13):3926-33. doi: 10.1016/j.neuropsychologia.2010.09.021. Epub 2010 Sep 25.

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