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EpCAM: structure and function in health and disease.

Schnell U, Cirulli V, Giepmans BN.

Biochim Biophys Acta. 2013 Aug;1828(8):1989-2001. doi: 10.1016/j.bbamem.2013.04.018. Epub 2013 Apr 23. Review.


EpCAM proteolysis: new fragments with distinct functions?

Schnell U, Kuipers J, Giepmans BN.

Biosci Rep. 2013 Mar 19;33(2):e00030. doi: 10.1042/BSR20120128.


Absence of cell-surface EpCAM in congenital tufting enteropathy.

Schnell U, Kuipers J, Mueller JL, Veenstra-Algra A, Sivagnanam M, Giepmans BN.

Hum Mol Genet. 2013 Jul 1;22(13):2566-71. doi: 10.1093/hmg/ddt105. Epub 2013 Mar 5.


Regulated intramembrane proteolysis and degradation of murine epithelial cell adhesion molecule mEpCAM.

Hachmeister M, Bobowski KD, Hogl S, Dislich B, Fukumori A, Eggert C, Mack B, Kremling H, Sarrach S, Coscia F, Zimmermann W, Steiner H, Lichtenthaler SF, Gires O.

PLoS One. 2013 Aug 29;8(8):e71836. doi: 10.1371/journal.pone.0071836. eCollection 2013.


Epithelial cell adhesion molecule expression (CD326) in cancer: a short review.

Patriarca C, Macchi RM, Marschner AK, Mellstedt H.

Cancer Treat Rev. 2012 Feb;38(1):68-75. doi: 10.1016/j.ctrv.2011.04.002. Epub 2011 May 14. Review.


EpCAM: another surface-to-nucleus missile.

Carpenter G, Red Brewer M.

Cancer Cell. 2009 Mar 3;15(3):165-6. doi: 10.1016/j.ccr.2009.02.005. Review.


Initial activation of EpCAM cleavage via cell-to-cell contact.

Denzel S, Maetzel D, Mack B, Eggert C, Bärr G, Gires O.

BMC Cancer. 2009 Nov 19;9:402. doi: 10.1186/1471-2407-9-402.


B-cell receptor-associated protein 31 regulates human embryonic stem cell adhesion, stemness, and survival via control of epithelial cell adhesion molecule.

Kim WT, Seo Choi H, Min Lee H, Jang YJ, Ryu CJ.

Stem Cells. 2014 Oct;32(10):2626-41. doi: 10.1002/stem.1765.


Nuclear signalling by tumour-associated antigen EpCAM.

Maetzel D, Denzel S, Mack B, Canis M, Went P, Benk M, Kieu C, Papior P, Baeuerle PA, Munz M, Gires O.

Nat Cell Biol. 2009 Feb;11(2):162-71. doi: 10.1038/ncb1824. Epub 2009 Jan 11.


EpCAM and the biology of hepatic stem/progenitor cells.

Dollé L, Theise ND, Schmelzer E, Boulter L, Gires O, van Grunsven LA.

Am J Physiol Gastrointest Liver Physiol. 2015 Feb 15;308(4):G233-50. doi: 10.1152/ajpgi.00069.2014. Epub 2014 Dec 4. Review.


Cancer-associated epithelial cell adhesion molecule (EpCAM; CD326) enables epidermal Langerhans cell motility and migration in vivo.

Gaiser MR, Lämmermann T, Feng X, Igyarto BZ, Kaplan DH, Tessarollo L, Germain RN, Udey MC.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):E889-97. doi: 10.1073/pnas.1117674109. Epub 2012 Mar 12. Erratum in: Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):E2095.


Frequent EpCam protein expression in human carcinomas.

Went PT, Lugli A, Meier S, Bundi M, Mirlacher M, Sauter G, Dirnhofer S.

Hum Pathol. 2004 Jan;35(1):122-8.


Claudin-7 regulates EpCAM-mediated functions in tumor progression.

Nübel T, Preobraschenski J, Tuncay H, Weiss T, Kuhn S, Ladwein M, Langbein L, Zöller M.

Mol Cancer Res. 2009 Mar;7(3):285-99. doi: 10.1158/1541-7786.MCR-08-0200. Epub 2009 Mar 10.


Functional consequences of EpCam mutation in mice and men.

Mueller JL, McGeough MD, Peña CA, Sivagnanam M.

Am J Physiol Gastrointest Liver Physiol. 2014 Feb 15;306(4):G278-88. doi: 10.1152/ajpgi.00286.2013. Epub 2013 Dec 12.


EpCAM: A new therapeutic target for an old cancer antigen.

Armstrong A, Eck SL.

Cancer Biol Ther. 2003 Jul-Aug;2(4):320-6. Review.


Epithelial cell adhesion molecule: more than a carcinoma marker and adhesion molecule.

Trzpis M, McLaughlin PM, de Leij LM, Harmsen MC.

Am J Pathol. 2007 Aug;171(2):386-95. Epub 2007 Jun 28. Review.


mTrop1/Epcam knockout mice develop congenital tufting enteropathy through dysregulation of intestinal E-cadherin/β-catenin.

Guerra E, Lattanzio R, La Sorda R, Dini F, Tiboni GM, Piantelli M, Alberti S.

PLoS One. 2012;7(11):e49302. doi: 10.1371/journal.pone.0049302. Epub 2012 Nov 28. Erratum in: PLoS One. 2013;8(5). doi:10.1371/annotation/4336e050-68c3-48ef-869e-80c2232b7e65.


Epithelial cell adhesion molecule (EpCAM) complex proteins promote transcription factor-mediated pluripotency reprogramming.

Huang HP, Chen PH, Yu CY, Chuang CY, Stone L, Hsiao WC, Li CL, Tsai SC, Chen KY, Chen HF, Ho HN, Kuo HC.

J Biol Chem. 2011 Sep 23;286(38):33520-32. doi: 10.1074/jbc.M111.256164. Epub 2011 Jul 28.


Epithelial cell adhesion molecule (EpCAM) regulates claudin dynamics and tight junctions.

Wu CJ, Mannan P, Lu M, Udey MC.

J Biol Chem. 2013 Apr 26;288(17):12253-68. doi: 10.1074/jbc.M113.457499. Epub 2013 Mar 13.

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