Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 74

1.

Biochemistry: Sirtuin on a high-fat diet.

Bheda P, Wolberger C.

Nature. 2013 Apr 4;496(7443):41-2. doi: 10.1038/496041a. No abstract available.

PMID:
23552941
2.

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine.

Jiang H, Khan S, Wang Y, Charron G, He B, Sebastian C, Du J, Kim R, Ge E, Mostoslavsky R, Hang HC, Hao Q, Lin H.

Nature. 2013 Apr 4;496(7443):110-3. doi: 10.1038/nature12038.

3.

Activation of the protein deacetylase SIRT6 by long-chain fatty acids and widespread deacylation by mammalian sirtuins.

Feldman JL, Baeza J, Denu JM.

J Biol Chem. 2013 Oct 25;288(43):31350-6. doi: 10.1074/jbc.C113.511261. Epub 2013 Sep 18.

4.

Sirtuin mechanism and inhibition: explored with N(ε)-acetyl-lysine analogs.

Hirsch BM, Zheng W.

Mol Biosyst. 2011 Jan;7(1):16-28. doi: 10.1039/c0mb00033g. Epub 2010 Sep 15. Review.

PMID:
20842312
5.

Capillary electrophoresis-based sirtuin assay using non-peptide substrates.

Fan Y, Hense M, Ludewig R, Weisgerber C, Scriba GK.

J Pharm Biomed Anal. 2011 Mar 25;54(4):772-8. doi: 10.1016/j.jpba.2010.10.010. Epub 2010 Oct 21.

PMID:
21074959
6.

N(epsilon)-methanesulfonyl-lysine as a non-hydrolyzable functional surrogate for N(epsilon)-acetyl-lysine.

Jamonnak N, Fatkins DG, Wei L, Zheng W.

Org Biomol Chem. 2007 Mar 21;5(6):892-6. Epub 2007 Feb 5.

PMID:
17340003
7.

A fluorogenic assay for screening Sirt6 modulators.

Hu J, He B, Bhargava S, Lin H.

Org Biomol Chem. 2013 Aug 28;11(32):5213-6. doi: 10.1039/c3ob41138a.

8.

Detecting sirtuin-catalyzed deacylation reactions using ³²P-labeled NAD and thin-layer chromatography.

Zhu A, Su X, Lin H.

Methods Mol Biol. 2013;1077:179-89. doi: 10.1007/978-1-62703-637-5_12.

PMID:
24014407
9.

Nepsilon-thioacetyl-lysine: a multi-facet functional probe for enzymatic protein lysine Nepsilon-deacetylation.

Fatkins DG, Monnot AD, Zheng W.

Bioorg Med Chem Lett. 2006 Jul 15;16(14):3651-6. Epub 2006 May 12.

PMID:
16697640
10.

Sir2 deacetylases exhibit nucleophilic participation of acetyl-lysine in NAD+ cleavage.

Smith BC, Denu JM.

J Am Chem Soc. 2007 May 9;129(18):5802-3. Epub 2007 Apr 17. No abstract available.

11.

Oxygen flux analysis to understand the biological function of sirtuins.

Wang D, Green MF, McDonnell E, Hirschey MD.

Methods Mol Biol. 2013;1077:241-58. doi: 10.1007/978-1-62703-637-5_16.

12.

Sirtuin chemical mechanisms.

Sauve AA.

Biochim Biophys Acta. 2010 Aug;1804(8):1591-603. doi: 10.1016/j.bbapap.2010.01.021. Epub 2010 Feb 2. Review.

13.

Identification of a cell-active non-peptide sirtuin inhibitor containing N-thioacetyl lysine.

Suzuki T, Asaba T, Imai E, Tsumoto H, Nakagawa H, Miyata N.

Bioorg Med Chem Lett. 2009 Oct 1;19(19):5670-2. doi: 10.1016/j.bmcl.2009.08.028. Epub 2009 Aug 12.

PMID:
19700324
14.

Inhibition of human sirtuins by in situ generation of an acetylated lysine-ADP-ribose conjugate.

Asaba T, Suzuki T, Ueda R, Tsumoto H, Nakagawa H, Miyata N.

J Am Chem Soc. 2009 May 27;131(20):6989-96. doi: 10.1021/ja807083y.

PMID:
19413317
15.

Acetyl-lysine analog peptides as mechanistic probes of protein deacetylases.

Smith BC, Denu JM.

J Biol Chem. 2007 Dec 21;282(51):37256-65. Epub 2007 Oct 19.

16.

SIRT4 represses peroxisome proliferator-activated receptor α activity to suppress hepatic fat oxidation.

Laurent G, de Boer VC, Finley LW, Sweeney M, Lu H, Schug TT, Cen Y, Jeong SM, Li X, Sauve AA, Haigis MC.

Mol Cell Biol. 2013 Nov;33(22):4552-61. doi: 10.1128/MCB.00087-13. Epub 2013 Sep 16.

17.

NAD+-dependent sirtuin 1 and 6 proteins coordinate a switch from glucose to fatty acid oxidation during the acute inflammatory response.

Liu TF, Vachharajani VT, Yoza BK, McCall CE.

J Biol Chem. 2012 Jul 27;287(31):25758-69. doi: 10.1074/jbc.M112.362343. Epub 2012 Jun 14.

18.

Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function.

Sadhukhan S, Liu X, Ryu D, Nelson OD, Stupinski JA, Li Z, Chen W, Zhang S, Weiss RS, Locasale JW, Auwerx J, Lin H.

Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4320-5. doi: 10.1073/pnas.1519858113. Epub 2016 Apr 5.

19.

Dietary restriction increases site-specific histone H3 acetylation in rat liver: possible modulation by sirtuins.

Kawakami K, Nakamura A, Goto S.

Biochem Biophys Res Commun. 2012 Feb 24;418(4):836-40. doi: 10.1016/j.bbrc.2012.01.120. Epub 2012 Jan 31.

PMID:
22321393
20.

Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling.

Alrob OA, Sankaralingam S, Ma C, Wagg CS, Fillmore N, Jaswal JS, Sack MN, Lehner R, Gupta MP, Michelakis ED, Padwal RS, Johnstone DE, Sharma AM, Lopaschuk GD.

Cardiovasc Res. 2014 Sep 1;103(4):485-97. doi: 10.1093/cvr/cvu156. Epub 2014 Jun 25.

Supplemental Content

Support Center