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Items: 1 to 20 of 113


The pluripotency factor-bound intron 1 of Xist is dispensable for X chromosome inactivation and reactivation in vitro and in vivo.

Minkovsky A, Barakat TS, Sellami N, Chin MH, Gunhanlar N, Gribnau J, Plath K.

Cell Rep. 2013 Mar 28;3(3):905-18. doi: 10.1016/j.celrep.2013.02.018. Epub 2013 Mar 21.


Molecular coupling of Tsix regulation and pluripotency.

Navarro P, Oldfield A, Legoupi J, Festuccia N, Dubois A, Attia M, Schoorlemmer J, Rougeulle C, Chambers I, Avner P.

Nature. 2010 Nov 18;468(7322):457-60. doi: 10.1038/nature09496.


Tsix RNA and the germline factor, PRDM14, link X reactivation and stem cell reprogramming.

Payer B, Rosenberg M, Yamaji M, Yabuta Y, Koyanagi-Aoi M, Hayashi K, Yamanaka S, Saitou M, Lee JT.

Mol Cell. 2013 Dec 26;52(6):805-18. doi: 10.1016/j.molcel.2013.10.023. Epub 2013 Nov 21.


The BET family member BRD4 interacts with OCT4 and regulates pluripotency gene expression.

Wu T, Pinto HB, Kamikawa YF, Donohoe ME.

Stem Cell Reports. 2015 Mar 10;4(3):390-403. doi: 10.1016/j.stemcr.2015.01.012. Epub 2015 Feb 12.


RNF12 activates Xist and is essential for X chromosome inactivation.

Barakat TS, Gunhanlar N, Pardo CG, Achame EM, Ghazvini M, Boers R, Kenter A, Rentmeester E, Grootegoed JA, Gribnau J.

PLoS Genet. 2011 Jan 27;7(1):e1002001. doi: 10.1371/journal.pgen.1002001.


Molecular coupling of Xist regulation and pluripotency.

Navarro P, Chambers I, Karwacki-Neisius V, Chureau C, Morey C, Rougeulle C, Avner P.

Science. 2008 Sep 19;321(5896):1693-5. doi: 10.1126/science.1160952.


Coupling of X-chromosome reactivation with the pluripotent stem cell state.

Payer B, Lee JT.

RNA Biol. 2014;11(7):798-807. doi: 10.4161/rna.29779. Epub 2014 Aug 19.


Xist gene regulation at the onset of X inactivation.

Senner CE, Brockdorff N.

Curr Opin Genet Dev. 2009 Apr;19(2):122-6. doi: 10.1016/j.gde.2009.03.003. Epub 2009 Apr 1. Review.


Histone demethylation maintains Prdm14 and Tsix expression and represses xIst in embryonic stem cells.

Kamikawa YF, Donohoe ME.

PLoS One. 2015 May 20;10(5):e0125626. doi: 10.1371/journal.pone.0125626. eCollection 2015.


The trans-activator RNF12 and cis-acting elements effectuate X chromosome inactivation independent of X-pairing.

Barakat TS, Loos F, van Staveren S, Myronova E, Ghazvini M, Grootegoed JA, Gribnau J.

Mol Cell. 2014 Mar 20;53(6):965-78. doi: 10.1016/j.molcel.2014.02.006. Epub 2014 Mar 6.


Sex-specific silencing of X-linked genes by Xist RNA.

Gayen S, Maclary E, Hinten M, Kalantry S.

Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):E309-18. doi: 10.1073/pnas.1515971113. Epub 2016 Jan 6.


The X-inactivation trans-activator Rnf12 is negatively regulated by pluripotency factors in embryonic stem cells.

Navarro P, Moffat M, Mullin NP, Chambers I.

Hum Genet. 2011 Aug;130(2):255-64. doi: 10.1007/s00439-011-0998-5. Epub 2011 May 5.


Pluripotency factor binding and Tsix expression act synergistically to repress Xist in undifferentiated embryonic stem cells.

Nesterova TB, Senner CE, Schneider J, Alcayna-Stevens T, Tattermusch A, Hemberger M, Brockdorff N.

Epigenetics Chromatin. 2011 Oct 7;4(1):17. doi: 10.1186/1756-8935-4-17.


Synergy of Eed and Tsix in the repression of Xist gene and X-chromosome inactivation.

Shibata S, Yokota T, Wutz A.

EMBO J. 2008 Jul 9;27(13):1816-26. doi: 10.1038/emboj.2008.110. Epub 2008 May 29.


RNF12 initiates X-chromosome inactivation by targeting REX1 for degradation.

Gontan C, Achame EM, Demmers J, Barakat TS, Rentmeester E, van IJcken W, Grootegoed JA, Gribnau J.

Nature. 2012 Apr 29;485(7398):386-90. doi: 10.1038/nature11070.


Jpx RNA activates Xist by evicting CTCF.

Sun S, Del Rosario BC, Szanto A, Ogawa Y, Jeon Y, Lee JT.

Cell. 2013 Jun 20;153(7):1537-51. doi: 10.1016/j.cell.2013.05.028.


Xist RNA repeat E is essential for ASH2L recruitment to the inactive X and regulates histone modifications and escape gene expression.

Yue M, Ogawa A, Yamada N, Charles Richard JL, Barski A, Ogawa Y.

PLoS Genet. 2017 Jul 7;13(7):e1006890. doi: 10.1371/journal.pgen.1006890. eCollection 2017 Jul.


MOF-associated complexes ensure stem cell identity and Xist repression.

Chelmicki T, Dündar F, Turley MJ, Khanam T, Aktas T, Ramírez F, Gendrel AV, Wright PR, Videm P, Backofen R, Heard E, Manke T, Akhtar A.

Elife. 2014 May 19;3:e02024. doi: 10.7554/eLife.02024.


An essential role for the DXPas34 tandem repeat and Tsix transcription in the counting process of X chromosome inactivation.

Vigneau S, Augui S, Navarro P, Avner P, Clerc P.

Proc Natl Acad Sci U S A. 2006 May 9;103(19):7390-5. Epub 2006 Apr 28.

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