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Items: 1 to 20 of 291

1.

Biomarkers of residual disease, disseminated tumor cells, and metastases in the MMTV-PyMT breast cancer model.

Franci C, Zhou J, Jiang Z, Modrusan Z, Good Z, Jackson E, Kouros-Mehr H.

PLoS One. 2013;8(3):e58183. doi: 10.1371/journal.pone.0058183. Epub 2013 Mar 8.

2.

Global expression profiling identifies signatures of tumor virulence in MMTV-PyMT-transgenic mice: correlation to human disease.

Qiu TH, Chandramouli GV, Hunter KW, Alkharouf NW, Green JE, Liu ET.

Cancer Res. 2004 Sep 1;64(17):5973-81.

3.

Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion.

Williams TM, Medina F, Badano I, Hazan RB, Hutchinson J, Muller WJ, Chopra NG, Scherer PE, Pestell RG, Lisanti MP.

J Biol Chem. 2004 Dec 3;279(49):51630-46. Epub 2004 Sep 7.

4.

Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer.

Schwab LP, Peacock DL, Majumdar D, Ingels JF, Jensen LC, Smith KD, Cushing RC, Seagroves TN.

Breast Cancer Res. 2012 Jan 7;14(1):R6.

5.

Metastasis is an early event in mouse mammary carcinomas and is associated with cells bearing stem cell markers.

Weng D, Penzner JH, Song B, Koido S, Calderwood SK, Gong J.

Breast Cancer Res. 2012 Jan 25;14(1):R18.

6.

Metastasis is strongly reduced by the matrix metalloproteinase inhibitor Galardin in the MMTV-PymT transgenic breast cancer model.

Almholt K, Juncker-Jensen A, Laerum OD, Danø K, Johnsen M, Lund LR, Rømer J.

Mol Cancer Ther. 2008 Sep;7(9):2758-67. doi: 10.1158/1535-7163.MCT-08-0251.

7.

Isolation and molecular characterization of cancer stem cells in MMTV-Wnt-1 murine breast tumors.

Cho RW, Wang X, Diehn M, Shedden K, Chen GY, Sherlock G, Gurney A, Lewicki J, Clarke MF.

Stem Cells. 2008 Feb;26(2):364-71. Epub 2007 Nov 1.

8.

Accelerated preclinical testing using transplanted tumors from genetically engineered mouse breast cancer models.

Varticovski L, Hollingshead MG, Robles AI, Wu X, Cherry J, Munroe DJ, Lukes L, Anver MR, Carter JP, Borgel SD, Stotler H, Bonomi CA, Nunez NP, Hursting SD, Qiao W, Deng CX, Green JE, Hunter KW, Merlino G, Steeg PS, Wakefield LM, Barrett JC.

Clin Cancer Res. 2007 Apr 1;13(7):2168-77.

9.

MMTV-PyMT and Derived Met-1 Mouse Mammary Tumor Cells as Models for Studying the Role of the Androgen Receptor in Triple-Negative Breast Cancer Progression.

Christenson JL, Butterfield KT, Spoelstra NS, Norris JD, Josan JS, Pollock JA, McDonnell DP, Katzenellenbogen BS, Katzenellenbogen JA, Richer JK.

Horm Cancer. 2017 Apr;8(2):69-77. doi: 10.1007/s12672-017-0285-6. Epub 2017 Feb 13.

PMID:
28194662
10.

Systemic spread is an early step in breast cancer.

Hüsemann Y, Geigl JB, Schubert F, Musiani P, Meyer M, Burghart E, Forni G, Eils R, Fehm T, Riethmüller G, Klein CA.

Cancer Cell. 2008 Jan;13(1):58-68. doi: 10.1016/j.ccr.2007.12.003.

11.

Deletion of Cd151 reduces mammary tumorigenesis in the MMTV/PyMT mouse model.

Roselli S, Kahl RG, Copeland BT, Naylor MJ, Weidenhofer J, Muller WJ, Ashman LK.

BMC Cancer. 2014 Jul 11;14:509. doi: 10.1186/1471-2407-14-509.

13.

Cooperative signaling between Wnt1 and integrin-linked kinase induces accelerated breast tumor development.

Oloumi A, Maidan M, Lock FE, Tearle H, McKinney S, Muller WJ, Aparicio SA, Dedhar S.

Breast Cancer Res. 2010;12(3):R38. doi: 10.1186/bcr2592. Epub 2010 Jun 21.

14.

Integrated miRNA and mRNA expression profiling of mouse mammary tumor models identifies miRNA signatures associated with mammary tumor lineage.

Zhu M, Yi M, Kim CH, Deng C, Li Y, Medina D, Stephens RM, Green JE.

Genome Biol. 2011 Aug 16;12(8):R77. doi: 10.1186/gb-2011-12-8-r77.

15.

The identification of osteopontin as a metastasis-related gene product in a rodent mammary tumour model.

Oates AJ, Barraclough R, Rudland PS.

Oncogene. 1996 Jul 4;13(1):97-104.

PMID:
8700559
16.

Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice.

Decock J, Hendrickx W, Thirkettle S, Gutiérrez-Fernández A, Robinson SD, Edwards DR.

Breast Cancer Res. 2015 Mar 14;17:38. doi: 10.1186/s13058-015-0545-8.

17.

Development of a metastatic fluorescent Lewis Lung carcinoma mouse model: identification of mRNAs and microRNAs involved in tumor invasion.

Rask L, Fregil M, Høgdall E, Mitchelmore C, Eriksen J.

Gene. 2013 Mar 15;517(1):72-81. doi: 10.1016/j.gene.2012.12.083. Epub 2013 Jan 4.

PMID:
23296057
18.

Leaving home early: reexamination of the canonical models of tumor progression.

Weinberg RA.

Cancer Cell. 2008 Oct 7;14(4):283-4. doi: 10.1016/j.ccr.2008.09.009.

19.

Association of hst gene expression with metastatic phenotype in mouse mammary tumors.

Murakami A, Tanaka H, Matsuzawa A.

Cell Growth Differ. 1990 May;1(5):225-31.

20.

Maspin expression inversely correlates with breast tumor progression in MMTV/TGF-alpha transgenic mouse model.

Reddy KB, McGowen R, Schuger L, Visscher D, Sheng S.

Oncogene. 2001 Oct 4;20(45):6538-43.

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