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Items: 1 to 20 of 92

1.

Could MDMA Promote Stemness Characteristics in Mouse Embryonic Stem Cells via mGlu5 Metabotropic Glutamate Receptors?

Meamar R, Karamali F, Mousavi SA, Baharvand H, Nasr-Esfahani MH.

Cell J. 2012 Fall;14(3):185-92. Epub 2012 Dec 12.

2.

Endogenous activation of mGlu5 metabotropic glutamate receptors supports self-renewal of cultured mouse embryonic stem cells.

Cappuccio I, Spinsanti P, Porcellini A, Desiderati F, De Vita T, Storto M, Capobianco L, Battaglia G, Nicoletti F, Melchiorri D.

Neuropharmacology. 2005;49 Suppl 1:196-205.

PMID:
16023153
4.

Selective blockade of mGlu5 metabotropic glutamate receptors protects rat hepatocytes against hypoxic damage.

Storto M, de Grazia U, Knöpfel T, Canonico PL, Copani A, Richelmi P, Nicoletti F, Vairetti M.

Hepatology. 2000 Mar;31(3):649-55.

PMID:
10706555
5.

Chronic treatment with MPEP, an mGlu5 receptor antagonist, normalizes basal ganglia glutamate neurotransmission in L-DOPA-treated parkinsonian monkeys.

Morin N, Morissette M, Grégoire L, Gomez-Mancilla B, Gasparini F, Di Paolo T.

Neuropharmacology. 2013 Oct;73:216-31. doi: 10.1016/j.neuropharm.2013.05.028. Epub 2013 Jun 10.

PMID:
23756168
6.

Compensatory molecular and functional mechanisms in nervous system of the Grm1(crv4) mouse lacking the mGlu1 receptor: a model for motor coordination deficits.

Rossi PI, Musante I, Summa M, Pittaluga A, Emionite L, Ikehata M, Rastaldi MP, Ravazzolo R, Puliti A.

Cereb Cortex. 2013 Sep;23(9):2179-89. doi: 10.1093/cercor/bhs200. Epub 2012 Jul 12.

PMID:
22791805
7.

mGlu5 receptors and nociceptive function II. mGlu5 receptors functionally expressed on peripheral sensory neurones mediate inflammatory hyperalgesia.

Walker K, Reeve A, Bowes M, Winter J, Wotherspoon G, Davis A, Schmid P, Gasparini F, Kuhn R, Urban L.

Neuropharmacology. 2001;40(1):10-9.

PMID:
11077066
8.
9.

Gene expression profiling reveals the heterogeneous transcriptional activity of Oct3/4 and its possible interaction with Gli2 in mouse embryonic stem cells.

Li Y, Drnevich J, Akraiko T, Band M, Li D, Wang F, Matoba R, Tanaka TS.

Genomics. 2013 Nov-Dec;102(5-6):456-67. doi: 10.1016/j.ygeno.2013.09.004. Epub 2013 Oct 8.

10.

Insulin secretion is controlled by mGlu5 metabotropic glutamate receptors.

Storto M, Capobianco L, Battaglia G, Molinaro G, Gradini R, Riozzi B, Di Mambro A, Mitchell KJ, Bruno V, Vairetti MP, Rutter GA, Nicoletti F.

Mol Pharmacol. 2006 Apr;69(4):1234-41. Epub 2006 Jan 19.

11.
13.

Context-dependent regulation of embryonic stem cell differentiation by mGlu4 metabotropic glutamate receptors.

Cappuccio I, Verani R, Spinsanti P, Niccolini C, Gradini R, Costantino S, Nicoletti F, Melchiorri D.

Neuropharmacology. 2006 Sep;51(3):606-11. Epub 2006 Jun 27.

PMID:
16806298
14.

Metabotropic glutamate receptors regulate differentiation of embryonic stem cells into GABAergic neurons.

Sarichelou I, Cappuccio I, Ferranti F, Mosillo P, Ciceroni C, Sale P, Stocchi F, Battaglia G, Nicoletti F, Melchiorri D.

Cell Death Differ. 2008 Apr;15(4):700-7. doi: 10.1038/sj.cdd.4402298. Epub 2008 Jan 4.

15.

Antagonism at metabotropic glutamate 5 receptors inhibits nicotine- and cocaine-taking behaviours and prevents nicotine-triggered relapse to nicotine-seeking.

Tessari M, Pilla M, Andreoli M, Hutcheson DM, Heidbreder CA.

Eur J Pharmacol. 2004 Sep 19;499(1-2):121-33.

PMID:
15363959
16.

Somatostatin receptor type 2 contributes to the self-renewal of murine embryonic stem cells.

Xu XX, Zhang LH, Xie X.

Acta Pharmacol Sin. 2014 Aug;35(8):1023-30. doi: 10.1038/aps.2014.51. Epub 2014 Jul 7.

17.

The metabotropic glutamate receptor subtype 5 antagonist fenobam is analgesic and has improved in vivo selectivity compared with the prototypical antagonist 2-methyl-6-(phenylethynyl)-pyridine.

Montana MC, Cavallone LF, Stubbert KK, Stefanescu AD, Kharasch ED, Gereau RW 4th.

J Pharmacol Exp Ther. 2009 Sep;330(3):834-43. doi: 10.1124/jpet.109.154138. Epub 2009 Jun 10.

18.

Mutational analysis and molecular modeling of the binding pocket of the metabotropic glutamate 5 receptor negative modulator 2-methyl-6-(phenylethynyl)-pyridine.

Malherbe P, Kratochwil N, Zenner MT, Piussi J, Diener C, Kratzeisen C, Fischer C, Porter RH.

Mol Pharmacol. 2003 Oct;64(4):823-32.

19.

Interoceptive effects of alcohol require mGlu5 receptor activity in the nucleus accumbens.

Besheer J, Grondin JJ, Salling MC, Spanos M, Stevenson RA, Hodge CW.

J Neurosci. 2009 Jul 29;29(30):9582-91. doi: 10.1523/JNEUROSCI.2366-09.2009.

20.

Adequate concentration of B cell leukemia/lymphoma 3 (Bcl3) is required for pluripotency and self-renewal of mouse embryonic stem cells via downregulation of Nanog transcription.

Kang S, Yun J, Kim DY, Jung SY, Kim YJ, Park JH, Ji ST, Jang WB, Ha J, Kim JH, Baek SH, Kwon SM.

BMB Rep. 2018 Jan 16. pii: 4044. [Epub ahead of print]

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