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Items: 1 to 20 of 128

1.

The fumagillin biosynthetic gene cluster in Aspergillus fumigatus encodes a cryptic terpene cyclase involved in the formation of β-trans-bergamotene.

Lin HC, Chooi YH, Dhingra S, Xu W, Calvo AM, Tang Y.

J Am Chem Soc. 2013 Mar 27;135(12):4616-9. doi: 10.1021/ja312503y. Epub 2013 Mar 19.

2.

Generation of complexity in fungal terpene biosynthesis: discovery of a multifunctional cytochrome P450 in the fumagillin pathway.

Lin HC, Tsunematsu Y, Dhingra S, Xu W, Fukutomi M, Chooi YH, Cane DE, Calvo AM, Watanabe K, Tang Y.

J Am Chem Soc. 2014 Mar 19;136(11):4426-36. doi: 10.1021/ja500881e. Epub 2014 Mar 11.

3.

The fumagillin gene cluster, an example of hundreds of genes under veA control in Aspergillus fumigatus.

Dhingra S, Lind AL, Lin HC, Tang Y, Rokas A, Calvo AM.

PLoS One. 2013 Oct 7;8(10):e77147. doi: 10.1371/journal.pone.0077147. eCollection 2013.

4.

Prototype of an intertwined secondary-metabolite supercluster.

Wiemann P, Guo CJ, Palmer JM, Sekonyela R, Wang CC, Keller NP.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):17065-70. doi: 10.1073/pnas.1313258110. Epub 2013 Sep 30.

5.

Bacterium induces cryptic meroterpenoid pathway in the pathogenic fungus Aspergillus fumigatus.

König CC, Scherlach K, Schroeckh V, Horn F, Nietzsche S, Brakhage AA, Hertweck C.

Chembiochem. 2013 May 27;14(8):938-42. doi: 10.1002/cbic.201300070. Epub 2013 May 6.

PMID:
23649940
6.

The volatome of Aspergillus fumigatus.

Heddergott C, Calvo AM, Latgé JP.

Eukaryot Cell. 2014 Aug;13(8):1014-25. doi: 10.1128/EC.00074-14. Epub 2014 Jun 6.

7.

Functional Reconstitution of a Fungal Natural Product Gene Cluster by Advanced Genome Editing.

Weber J, Valiante V, Nødvig CS, Mattern DJ, Slotkowski RA, Mortensen UH, Brakhage AA.

ACS Synth Biol. 2017 Jan 20;6(1):62-68. doi: 10.1021/acssynbio.6b00203. Epub 2016 Sep 13.

PMID:
27611015
8.

Supercluster takes a walk on the wild side.

Nielsen JB, Andersen MR, Mortensen UH.

Trends Microbiol. 2013 Dec;21(12):617-8. doi: 10.1016/j.tim.2013.11.002. Epub 2013 Nov 14.

PMID:
24239205
9.

The developmental regulators, FlbB and FlbE, are involved in the virulence of Aspergillus fumigatus.

Kim SS, Kim YH, Shin KS.

J Microbiol Biotechnol. 2013 Jun 28;23(6):766-70.

10.
11.

Carbon and nitrogen source nutrition of fumagillin biosynthesis by Aspergillus fumigatus.

Yang W, Kim WS, Fang A, Demain AL.

Curr Microbiol. 2003 Apr;46(4):275-9.

PMID:
12732977
12.

A developmentally regulated gene cluster involved in conidial pigment biosynthesis in Aspergillus fumigatus.

Tsai HF, Wheeler MH, Chang YC, Kwon-Chung KJ.

J Bacteriol. 1999 Oct;181(20):6469-77.

13.

Culture condition-dependent metabolite profiling of Aspergillus fumigatus with antifungal activity.

Kang D, Son GH, Park HM, Kim J, Choi JN, Kim HY, Lee S, Hong SB, Lee CH.

Fungal Biol. 2013 Mar;117(3):211-9. doi: 10.1016/j.funbio.2013.01.009. Epub 2013 Feb 14.

PMID:
23537878
14.
15.

Fumagiringillin, a new fumagillin derivative from a strain of the fungus Aspergillus fumigatus.

Jiao W, Blunt JW, Cole AL, Munro MH.

J Nat Prod. 2004 Aug;67(8):1434-7.

PMID:
15332872
16.

Genome-based cluster deletion reveals an endocrocin biosynthetic pathway in Aspergillus fumigatus.

Lim FY, Hou Y, Chen Y, Oh JH, Lee I, Bugni TS, Keller NP.

Appl Environ Microbiol. 2012 Jun;78(12):4117-25. doi: 10.1128/AEM.07710-11. Epub 2012 Apr 6. Erratum in: Appl Environ Microbiol. 2012 Sep;78(17):6395.

17.

Identification of the antiphagocytic trypacidin gene cluster in the human-pathogenic fungus Aspergillus fumigatus.

Mattern DJ, Schoeler H, Weber J, Novohradská S, Kraibooj K, Dahse HM, Hillmann F, Valiante V, Figge MT, Brakhage AA.

Appl Microbiol Biotechnol. 2015 Dec;99(23):10151-61. doi: 10.1007/s00253-015-6898-1. Epub 2015 Aug 18.

PMID:
26278536
18.

Discovery of cryptic polyketide metabolites from dermatophytes using heterologous expression in Aspergillus nidulans.

Yin WB, Chooi YH, Smith AR, Cacho RA, Hu Y, White TC, Tang Y.

ACS Synth Biol. 2013 Nov 15;2(11):629-34. doi: 10.1021/sb400048b. Epub 2013 Jun 11.

19.

Redundant synthesis of a conidial polyketide by two distinct secondary metabolite clusters in Aspergillus fumigatus.

Throckmorton K, Lim FY, Kontoyiannis DP, Zheng W, Keller NP.

Environ Microbiol. 2016 Jan;18(1):246-59. doi: 10.1111/1462-2920.13007. Epub 2015 Sep 3.

20.

The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2.

Sin N, Meng L, Wang MQ, Wen JJ, Bornmann WG, Crews CM.

Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6099-103.

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