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Items: 1 to 20 of 249

1.

A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assembly.

Canzio D, Liao M, Naber N, Pate E, Larson A, Wu S, Marina DB, Garcia JF, Madhani HD, Cooke R, Schuck P, Cheng Y, Narlikar GJ.

Nature. 2013 Apr 18;496(7445):377-81. doi: 10.1038/nature12032.

2.

Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly.

Canzio D, Chang EY, Shankar S, Kuchenbecker KM, Simon MD, Madhani HD, Narlikar GJ, Al-Sady B.

Mol Cell. 2011 Jan 7;41(1):67-81. doi: 10.1016/j.molcel.2010.12.016.

3.

Diverse roles of HP1 proteins in heterochromatin assembly and functions in fission yeast.

Fischer T, Cui B, Dhakshnamoorthy J, Zhou M, Rubin C, Zofall M, Veenstra TD, Grewal SI.

Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):8998-9003. doi: 10.1073/pnas.0813063106.

4.

HP1(Swi6) mediates the recognition and destruction of heterochromatic RNA transcripts.

Keller C, Adaixo R, Stunnenberg R, Woolcock KJ, Hiller S, Bühler M.

Mol Cell. 2012 Jul 27;47(2):215-27. doi: 10.1016/j.molcel.2012.05.009.

5.

H3K9 methylation extends across natural boundaries of heterochromatin in the absence of an HP1 protein.

Stunnenberg R, Kulasegaran-Shylini R, Keller C, Kirschmann MA, Gelman L, Bühler M.

EMBO J. 2015 Nov 12;34(22):2789-803. doi: 10.15252/embj.201591320.

6.

Coordination of DNA replication and histone modification by the Rik1-Dos2 complex.

Li F, Martienssen R, Cande WZ.

Nature. 2011 Jul 3;475(7355):244-8. doi: 10.1038/nature10161.

7.

Role of Swi6/HP1 self-association-mediated recruitment of Clr4/Suv39 in establishment and maintenance of heterochromatin in fission yeast.

Haldar S, Saini A, Nanda JS, Saini S, Singh J.

J Biol Chem. 2011 Mar 18;286(11):9308-20. doi: 10.1074/jbc.M110.143198.

8.

HP1 proteins form distinct complexes and mediate heterochromatic gene silencing by nonoverlapping mechanisms.

Motamedi MR, Hong EJ, Li X, Gerber S, Denison C, Gygi S, Moazed D.

Mol Cell. 2008 Dec 26;32(6):778-90. doi: 10.1016/j.molcel.2008.10.026.

10.

Interaction of APC/C-E3 ligase with Swi6/HP1 and Clr4/Suv39 in heterochromatin assembly in fission yeast.

Dubey RN, Nakwal N, Bisht KK, Saini A, Haldar S, Singh J.

J Biol Chem. 2009 Mar 13;284(11):7165-76. doi: 10.1074/jbc.M806461200.

11.

Asf1/HIRA facilitate global histone deacetylation and associate with HP1 to promote nucleosome occupancy at heterochromatic loci.

Yamane K, Mizuguchi T, Cui B, Zofall M, Noma K, Grewal SI.

Mol Cell. 2011 Jan 7;41(1):56-66. doi: 10.1016/j.molcel.2010.12.009.

12.

Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain.

Bannister AJ, Zegerman P, Partridge JF, Miska EA, Thomas JO, Allshire RC, Kouzarides T.

Nature. 2001 Mar 1;410(6824):120-4.

PMID:
11242054
13.

Heterochromatin revisited.

Grewal SI, Jia S.

Nat Rev Genet. 2007 Jan;8(1):35-46. Review.

PMID:
17173056
14.

Abo1, a conserved bromodomain AAA-ATPase, maintains global nucleosome occupancy and organisation.

Gal C, Murton HE, Subramanian L, Whale AJ, Moore KM, Paszkiewicz K, Codlin S, Bähler J, Creamer KM, Partridge JF, Allshire RC, Kent NA, Whitehall SK.

EMBO Rep. 2016 Jan;17(1):79-93. doi: 10.15252/embr.201540476.

15.

A chromodomain switch mediated by histone H3 Lys 4 acetylation regulates heterochromatin assembly.

Xhemalce B, Kouzarides T.

Genes Dev. 2010 Apr 1;24(7):647-52. doi: 10.1101/gad.1881710.

16.

Division of labor between the chromodomains of HP1 and Suv39 methylase enables coordination of heterochromatin spread.

Al-Sady B, Madhani HD, Narlikar GJ.

Mol Cell. 2013 Jul 11;51(1):80-91. doi: 10.1016/j.molcel.2013.06.013.

17.

Epigenetic Regulation of Chromatin States in Schizosaccharomyces pombe.

Allshire RC, Ekwall K.

Cold Spring Harb Perspect Biol. 2015 Jul 1;7(7):a018770. doi: 10.1101/cshperspect.a018770. Review.

PMID:
26134317
18.

Centromere silencing and function in fission yeast is governed by the amino terminus of histone H3.

Mellone BG, Ball L, Suka N, Grunstein MR, Partridge JF, Allshire RC.

Curr Biol. 2003 Oct 14;13(20):1748-57.

19.

Balance between distinct HP1 family proteins controls heterochromatin assembly in fission yeast.

Sadaie M, Kawaguchi R, Ohtani Y, Arisaka F, Tanaka K, Shirahige K, Nakayama J.

Mol Cell Biol. 2008 Dec;28(23):6973-88. doi: 10.1128/MCB.00791-08.

20.

Phosphorylation of Swi6/HP1 regulates transcriptional gene silencing at heterochromatin.

Shimada A, Dohke K, Sadaie M, Shinmyozu K, Nakayama J, Urano T, Murakami Y.

Genes Dev. 2009 Jan 1;23(1):18-23. doi: 10.1101/gad.1708009.

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