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Items: 1 to 20 of 97

1.

Fragmented inositol 1,4,5-trisphosphate receptors retain tetrameric architecture and form functional Ca2+ release channels.

Alzayady KJ, Chandrasekhar R, Yule DI.

J Biol Chem. 2013 Apr 19;288(16):11122-34. doi: 10.1074/jbc.M113.453241. Epub 2013 Mar 11.

2.

Caspase-3-induced truncation of type 1 inositol trisphosphate receptor accelerates apoptotic cell death and induces inositol trisphosphate-independent calcium release during apoptosis.

Assefa Z, Bultynck G, Szlufcik K, Nadif Kasri N, Vermassen E, Goris J, Missiaen L, Callewaert G, Parys JB, De Smedt H.

J Biol Chem. 2004 Oct 8;279(41):43227-36. Epub 2004 Jul 28.

3.

The Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavage.

Schulman JJ, Wright FA, Kaufmann T, Wojcikiewicz RJ.

J Biol Chem. 2013 Aug 30;288(35):25340-9. doi: 10.1074/jbc.M113.496570. Epub 2013 Jul 24.

4.

Region-specific proteolysis differentially regulates type 1 inositol 1,4,5-trisphosphate receptor activity.

Wang L, Wagner LE 2nd, Alzayady KJ, Yule DI.

J Biol Chem. 2017 May 19. pii: jbc.M117.789917. doi: 10.1074/jbc.M117.789917. [Epub ahead of print]

5.

Calpain-cleaved type 1 inositol 1,4,5-trisphosphate receptor (InsP(3)R1) has InsP(3)-independent gating and disrupts intracellular Ca(2+) homeostasis.

Kopil CM, Vais H, Cheung KH, Siebert AP, Mak DO, Foskett JK, Neumar RW.

J Biol Chem. 2011 Oct 14;286(41):35998-6010. doi: 10.1074/jbc.M111.254177. Epub 2011 Aug 22.

6.

Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.

Alzayady KJ, Wagner LE 2nd, Chandrasekhar R, Monteagudo A, Godiska R, Tall GG, Joseph SK, Yule DI.

J Biol Chem. 2013 Oct 11;288(41):29772-84. doi: 10.1074/jbc.M113.502203. Epub 2013 Aug 16.

7.

80K-H interacts with inositol 1,4,5-trisphosphate (IP3) receptors and regulates IP3-induced calcium release activity.

Kawaai K, Hisatsune C, Kuroda Y, Mizutani A, Tashiro T, Mikoshiba K.

J Biol Chem. 2009 Jan 2;284(1):372-80. doi: 10.1074/jbc.M805828200. Epub 2008 Nov 6.

8.

Trypsinized cerebellar inositol 1,4,5-trisphosphate receptor. Structural and functional coupling of cleaved ligand binding and channel domains.

Yoshikawa F, Iwasaki H, Michikawa T, Furuichi T, Mikoshiba K.

J Biol Chem. 1999 Jan 1;274(1):316-27.

9.

Caspase-3-truncated type 1 inositol 1,4,5-trisphosphate receptor enhances intracellular Ca2+ leak and disturbs Ca2+ signalling.

Verbert L, Lee B, Kocks SL, Assefa Z, Parys JB, Missiaen L, Callewaert G, Fissore RA, De Smedt H, Bultynck G.

Biol Cell. 2008 Jan;100(1):39-49.

10.

The role of Ca2+ in triggering inositol 1,4,5-trisphosphate receptor ubiquitination.

Alzayady KJ, Wojcikiewicz RJ.

Biochem J. 2005 Dec 15;392(Pt 3):601-6.

11.
12.

Caspase 3 cleavage of the inositol 1,4,5-trisphosphate receptor does not contribute to apoptotic calcium release.

Akimzhanov AM, Barral JM, Boehning D.

Cell Calcium. 2013 Feb;53(2):152-8. doi: 10.1016/j.ceca.2012.10.002. Epub 2012 Nov 2.

13.

The regulatory domain of the inositol 1,4,5-trisphosphate receptor is necessary to keep the channel domain closed: possible physiological significance of specific cleavage by caspase 3.

Nakayama T, Hattori M, Uchida K, Nakamura T, Tateishi Y, Bannai H, Iwai M, Michikawa T, Inoue T, Mikoshiba K.

Biochem J. 2004 Jan 15;377(Pt 2):299-307.

14.

Proteolytic fragmentation of inositol 1,4,5-trisphosphate receptors: a novel mechanism regulating channel activity?

Wang L, Alzayady KJ, Yule DI.

J Physiol. 2016 Jun 1;594(11):2867-76. doi: 10.1113/JP271140. Epub 2015 Dec 7.

PMID:
26486785
15.

The IP3 receptor/Ca2+ channel and its cellular function.

Mikoshiba K.

Biochem Soc Symp. 2007;(74):9-22. Review.

PMID:
17233576
16.
17.

Regulation of the type 1 inositol 1,4,5-trisphosphate receptor by phosphorylation at tyrosine 353.

Cui J, Matkovich SJ, deSouza N, Li S, Rosemblit N, Marks AR.

J Biol Chem. 2004 Apr 16;279(16):16311-6. Epub 2004 Feb 3.

18.

Role of inositol 1,4,5-trisphosphate receptors in apoptosis in DT40 lymphocytes.

Khan MT, Bhanumathy CD, Schug ZT, Joseph SK.

J Biol Chem. 2007 Nov 9;282(45):32983-90. Epub 2007 Sep 17.

19.

Thimerosal stimulates Ca2+ flux through inositol 1,4,5-trisphosphate receptor type 1, but not type 3, via modulation of an isoform-specific Ca2+-dependent intramolecular interaction.

Bultynck G, Szlufcik K, Kasri NN, Assefa Z, Callewaert G, Missiaen L, Parys JB, De Smedt H.

Biochem J. 2004 Jul 1;381(Pt 1):87-96.

20.

Intracellular calcium-release channels: regulators of cell life and death.

Marks AR.

Am J Physiol. 1997 Feb;272(2 Pt 2):H597-605. Review.

PMID:
9124414

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