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Items: 1 to 20 of 115

1.

B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile.

DeFuria J, Belkina AC, Jagannathan-Bogdan M, Snyder-Cappione J, Carr JD, Nersesova YR, Markham D, Strissel KJ, Watkins AA, Zhu M, Allen J, Bouchard J, Toraldo G, Jasuja R, Obin MS, McDonnell ME, Apovian C, Denis GV, Nikolajczyk BS.

Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5133-8. doi: 10.1073/pnas.1215840110. Epub 2013 Mar 11.

2.

B cells promote obesity-associated periodontitis and oral pathogen-associated inflammation.

Zhu M, Belkina AC, DeFuria J, Carr JD, Van Dyke TE, Gyurko R, Nikolajczyk BS.

J Leukoc Biol. 2014 Aug;96(2):349-57. doi: 10.1189/jlb.4A0214-095R. Epub 2014 Apr 29.

3.

Elevated proinflammatory cytokine production by a skewed T cell compartment requires monocytes and promotes inflammation in type 2 diabetes.

Jagannathan-Bogdan M, McDonnell ME, Shin H, Rehman Q, Hasturk H, Apovian CM, Nikolajczyk BS.

J Immunol. 2011 Jan 15;186(2):1162-72. doi: 10.4049/jimmunol.1002615. Epub 2010 Dec 17.

4.

DNA methylation is altered in B and NK lymphocytes in obese and type 2 diabetic human.

Simar D, Versteyhe S, Donkin I, Liu J, Hesson L, Nylander V, Fossum A, Barrès R.

Metabolism. 2014 Sep;63(9):1188-97. doi: 10.1016/j.metabol.2014.05.014. Epub 2014 Jun 4.

5.

Potential role of regulatory T cells in reversing obesity-linked insulin resistance and diabetic nephropathy.

Eller K, Kirsch A, Wolf AM, Sopper S, Tagwerker A, Stanzl U, Wolf D, Patsch W, Rosenkranz AR, Eller P.

Diabetes. 2011 Nov;60(11):2954-62. doi: 10.2337/db11-0358. Epub 2011 Sep 12.

6.

B Lymphocytes in obesity-related adipose tissue inflammation and insulin resistance.

Winer DA, Winer S, Chng MH, Shen L, Engleman EG.

Cell Mol Life Sci. 2014 Mar;71(6):1033-43. doi: 10.1007/s00018-013-1486-y. Epub 2013 Oct 15. Review.

7.

Monocytes play different roles in stimulating T cells in obese diabetic individuals.

Dai X, Zhan J, Demmy TA, Poordad FB, Fauceglia PL, Zhang H, Wu L.

Int J Immunopathol Pharmacol. 2015 Sep;28(3):374-83. doi: 10.1177/0394632015598848. Epub 2015 Aug 5.

PMID:
26246197
8.

Adipose tissue inflammation in the pathogenesis of type 2 diabetes.

Kohlgruber A, Lynch L.

Curr Diab Rep. 2015 Nov;15(11):92. doi: 10.1007/s11892-015-0670-x. Review.

PMID:
26374569
9.

Increased oxidative stress and the apoptosis of regulatory T cells in obese mice but not resistant mice in response to a high-fat diet.

Wang B, Sun J, Ma Y, Wu G, Shi Y, Le G.

Cell Immunol. 2014 Mar-Apr;288(1-2):39-46. doi: 10.1016/j.cellimm.2014.02.003. Epub 2014 Feb 28.

PMID:
24637087
10.

The "Big Bang" in obese fat: Events initiating obesity-induced adipose tissue inflammation.

Wensveen FM, Valentić S, Šestan M, Turk Wensveen T, Polić B.

Eur J Immunol. 2015 Sep;45(9):2446-56. doi: 10.1002/eji.201545502. Epub 2015 Aug 19. Review.

11.

State of the union between metabolism and the immune system in type 2 diabetes.

Nikolajczyk BS, Jagannathan-Bogdan M, Shin H, Gyurko R.

Genes Immun. 2011 Jun;12(4):239-50. doi: 10.1038/gene.2011.14. Epub 2011 Mar 10. Review.

PMID:
21390053
12.

Visceral adipose inflammation in obesity is associated with critical alterations in tregulatory cell numbers.

Deiuliis J, Shah Z, Shah N, Needleman B, Mikami D, Narula V, Perry K, Hazey J, Kampfrath T, Kollengode M, Sun Q, Satoskar AR, Lumeng C, Moffatt-Bruce S, Rajagopalan S.

PLoS One. 2011 Jan 26;6(1):e16376. doi: 10.1371/journal.pone.0016376.

13.

Adipose tissue-resident regulatory T cells: phenotypic specialization, functions and therapeutic potential.

Cipolletta D.

Immunology. 2014 Aug;142(4):517-25. doi: 10.1111/imm.12262. Review.

14.

Th17 cytokines differentiate obesity from obesity-associated type 2 diabetes and promote TNFα production.

Ip B, Cilfone NA, Belkina AC, DeFuria J, Jagannathan-Bogdan M, Zhu M, Kuchibhatla R, McDonnell ME, Xiao Q, Kepler TB, Apovian CM, Lauffenburger DA, Nikolajczyk BS.

Obesity (Silver Spring). 2016 Jan;24(1):102-12. doi: 10.1002/oby.21243. Epub 2015 Nov 18.

15.

Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob mice.

Ilan Y, Maron R, Tukpah AM, Maioli TU, Murugaiyan G, Yang K, Wu HY, Weiner HL.

Proc Natl Acad Sci U S A. 2010 May 25;107(21):9765-70. doi: 10.1073/pnas.0908771107. Epub 2010 May 5.

16.

Elevated B Cell Activation is Associated with Type 2 Diabetes Development in Obese Subjects.

Zhai X, Qian G, Wang Y, Chen X, Lu J, Zhang Y, Huang Q, Wang Q.

Cell Physiol Biochem. 2016;38(3):1257-66. doi: 10.1159/000443073. Epub 2016 Mar 17.

17.

The outliers become a stampede as immunometabolism reaches a tipping point.

Nikolajczyk BS, Jagannathan-Bogdan M, Denis GV.

Immunol Rev. 2012 Sep;249(1):253-75. doi: 10.1111/j.1600-065X.2012.01142.x. Review.

18.

Insulin inhibits IL-10-mediated regulatory T cell function: implications for obesity.

Han JM, Patterson SJ, Speck M, Ehses JA, Levings MK.

J Immunol. 2014 Jan 15;192(2):623-9. doi: 10.4049/jimmunol.1302181. Epub 2013 Dec 9.

19.

Metabolism: Contribution of B cells to obesity and insulin resistance.

Greenhill C.

Nat Rev Endocrinol. 2013 Jun;9(6):315. doi: 10.1038/nrendo.2013.69. Epub 2013 Apr 2. No abstract available.

PMID:
23545488
20.

MAP4K4 and IL-6+ Th17 cells play important roles in non-obese type 2 diabetes.

Chuang HC, Tan TH.

J Biomed Sci. 2017 Jan 7;24(1):4. doi: 10.1186/s12929-016-0307-7. Review.

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