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Items: 1 to 20 of 109

1.

Lactate dehydrogenase-B is silenced by promoter methylation in a high frequency of human breast cancers.

Brown NJ, Higham SE, Perunovic B, Arafa M, Balasubramanian S, Rehman I.

PLoS One. 2013;8(2):e57697. doi: 10.1371/journal.pone.0057697. Epub 2013 Feb 21.

3.

Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis.

Borges S, Döppler H, Perez EA, Andorfer CA, Sun Z, Anastasiadis PZ, Thompson E, Geiger XJ, Storz P.

Breast Cancer Res. 2013 Aug 23;15(2):R66. doi: 10.1186/bcr3460.

4.

Lactate dehydrogenase-B is silenced by promoter hypermethylation in human prostate cancer.

Leiblich A, Cross SS, Catto JW, Phillips JT, Leung HY, Hamdy FC, Rehman I.

Oncogene. 2006 May 11;25(20):2953-60.

PMID:
16547507
5.

Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth.

Zhao YH, Zhou M, Liu H, Ding Y, Khong HT, Yu D, Fodstad O, Tan M.

Oncogene. 2009 Oct 22;28(42):3689-701. doi: 10.1038/onc.2009.229. Epub 2009 Aug 10.

PMID:
19668225
6.

Aberrant DNA methylation but not mutation of CITED4 is associated with alteration of HIF-regulated genes in breast cancer.

Huang KT, Takano EA, Mikeska T, Byrne DJ, Dobrovic A, Fox SB.

Breast Cancer Res Treat. 2011 Nov;130(1):319-29. doi: 10.1007/s10549-011-1657-1. Epub 2011 Jul 14.

PMID:
21755341
7.

Methylation and gene silencing of the Ras-related GTPase gene in lung and breast cancers.

Suzuki M, Shigematsu H, Shames DS, Sunaga N, Takahashi T, Shivapurkar N, Iizasa T, Minna JD, Fujisawa T, Gazdar AF.

Ann Surg Oncol. 2007 Apr;14(4):1397-404. Epub 2006 Dec 29.

PMID:
17195088
8.

Targeting aspartate aminotransferase in breast cancer.

Thornburg JM, Nelson KK, Clem BF, Lane AN, Arumugam S, Simmons A, Eaton JW, Telang S, Chesney J.

Breast Cancer Res. 2008;10(5):R84. doi: 10.1186/bcr2154. Epub 2008 Oct 15.

9.

5' CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer.

Zöchbauer-Müller S, Fong KM, Maitra A, Lam S, Geradts J, Ashfaq R, Virmani AK, Milchgrub S, Gazdar AF, Minna JD.

Cancer Res. 2001 May 1;61(9):3581-5.

10.

LDH-A silencing suppresses breast cancer tumorigenicity through induction of oxidative stress mediated mitochondrial pathway apoptosis.

Wang ZY, Loo TY, Shen JG, Wang N, Wang DM, Yang DP, Mo SL, Guan XY, Chen JP.

Breast Cancer Res Treat. 2012 Feb;131(3):791-800. doi: 10.1007/s10549-011-1466-6. Epub 2011 Mar 31.

PMID:
21452021
11.

DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines.

Roll JD, Rivenbark AG, Jones WD, Coleman WB.

Mol Cancer. 2008 Jan 25;7:15. doi: 10.1186/1476-4598-7-15.

12.

Frequent epigenetic inactivation of the receptor tyrosine kinase EphA5 by promoter methylation in human breast cancer.

Fu DY, Wang ZM, Wang BL, Chen L, Yang WT, Shen ZZ, Huang W, Shao ZM.

Hum Pathol. 2010 Jan;41(1):48-58. doi: 10.1016/j.humpath.2009.06.007. Epub 2009 Sep 5.

PMID:
19733895
13.

Tyrosine phosphorylation of lactate dehydrogenase A is important for NADH/NAD(+) redox homeostasis in cancer cells.

Fan J, Hitosugi T, Chung TW, Xie J, Ge Q, Gu TL, Polakiewicz RD, Chen GZ, Boggon TJ, Lonial S, Khuri FR, Kang S, Chen J.

Mol Cell Biol. 2011 Dec;31(24):4938-50. doi: 10.1128/MCB.06120-11. Epub 2011 Oct 3.

14.

Wnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours.

Veeck J, Bektas N, Hartmann A, Kristiansen G, Heindrichs U, Knüchel R, Dahl E.

Breast Cancer Res. 2008;10(5):R82. doi: 10.1186/bcr2151. Epub 2008 Sep 30.

15.

Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer.

Fujikane T, Nishikawa N, Toyota M, Suzuki H, Nojima M, Maruyama R, Ashida M, Ohe-Toyota M, Kai M, Nishidate T, Sasaki Y, Ohmura T, Hirata K, Tokino T.

Breast Cancer Res Treat. 2010 Aug;122(3):699-710. doi: 10.1007/s10549-009-0600-1. Epub 2009 Oct 27.

PMID:
19859801
16.

Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers.

Zou B, Chim CS, Zeng H, Leung SY, Yang Y, Tu SP, Lin MC, Wang J, He H, Jiang SH, Sun YW, Yu LF, Yuen ST, Kung HF, Wong BC.

Gastroenterology. 2006 Dec;131(6):1835-43. Epub 2006 Oct 1.

PMID:
17087954
17.

[Promoter methylation and mRNA expression of WT1 gene in MCF10 breast cancer model].

Yang JL, Klinkebiel D, Boland MJ, Tang L, Christman JK.

Zhonghua Bing Li Xue Za Zhi. 2007 Apr;36(4):253-8. Chinese.

PMID:
17706117
18.

Aberrant promoter methylation and silencing of laminin-5-encoding genes in breast carcinoma.

Sathyanarayana UG, Padar A, Huang CX, Suzuki M, Shigematsu H, Bekele BN, Gazdar AF.

Clin Cancer Res. 2003 Dec 15;9(17):6389-94.

19.

Regulation of human Cripto-1 expression by nuclear receptors and DNA promoter methylation in human embryonal and breast cancer cells.

Bianco C, Castro NP, Baraty C, Rollman K, Held N, Rangel MC, Karasawa H, Gonzales M, Strizzi L, Salomon DS.

J Cell Physiol. 2013 Jun;228(6):1174-88. doi: 10.1002/jcp.24271.

20.

FOXM1 promotes the warburg effect and pancreatic cancer progression via transactivation of LDHA expression.

Cui J, Shi M, Xie D, Wei D, Jia Z, Zheng S, Gao Y, Huang S, Xie K.

Clin Cancer Res. 2014 May 15;20(10):2595-606. doi: 10.1158/1078-0432.CCR-13-2407. Epub 2014 Mar 14.

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