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Early decrease of serum biomarkers of type II collagen degradation (Coll2-1) and joint inflammation (Coll2-1 NO₂ ) by hyaluronic acid intra-articular injections in patients with knee osteoarthritis: a research study part of the Biovisco study.

Henrotin Y, Chevalier X, Deberg M, Balblanc JC, Richette P, Mulleman D, Maillet B, Rannou F, Piroth C, Mathieu P, Conrozier T; Osteoarthritis Group of French Society of Rheumatology..

J Orthop Res. 2013 Jun;31(6):901-7. doi: 10.1002/jor.22297. Epub 2013 Feb 19.


Early effect of hyaluronic acid intra-articular injections on serum and urine biomarkers in patients with knee osteoarthritis: An open-label observational prospective study.

Conrozier T, Balblanc JC, Richette P, Mulleman D, Maillet B, Henrotin Y, Rannou F, Piroth C, Hilliquin P, Mathieu P, Walliser-Lohse A, Rousselot I, Plattner V, Maillefert JF, Vignon E, Chevalier X; Osteoarthritis Group of the French Society of Rheumatology..

J Orthop Res. 2012 May;30(5):679-85. doi: 10.1002/jor.21580. Epub 2011 Oct 24.


One-year follow-up of Coll2-1, Coll2-1NO2 and myeloperoxydase serum levels in osteoarthritis patients after hip or knee replacement.

Deberg M, Dubuc JE, Labasse A, Sanchez C, Quettier E, Bosseloir A, Crielaard JM, Henrotin Y.

Ann Rheum Dis. 2008 Feb;67(2):168-74. Epub 2007 Jul 20.


The chemical biomarkers C2C, Coll2-1, and Coll2-1NO2 provide complementary information on type II collagen catabolism in healthy and osteoarthritic mice.

Ameye LG, Deberg M, Oliveira M, Labasse A, Aeschlimann JM, Henrotin Y.

Arthritis Rheum. 2007 Oct;56(10):3336-46.


Prospective, multi-centre, randomised evaluation of the safety and efficacy of five dosing regimens of viscosupplementation with hylan G-F 20 in patients with symptomatic tibio-femoral osteoarthritis: a pilot study.

Conrozier T, Jerosch J, Beks P, Kemper F, Euller-Ziegler L, Bailleul F, Chevalier X.

Arch Orthop Trauma Surg. 2009 Mar;129(3):417-23. doi: 10.1007/s00402-008-0601-2. Epub 2008 Mar 26.


[Effectiveness and safety of intra-articular use of hyaluronic acid (Suplasyn) in the treatment of knee osteoarthritis].

Gadek A, Miśkowiec K, Wordliczek J, Liszka H.

Przegl Lek. 2011;68(6):307-10. Polish.


A 40-month multicentre, randomised placebo-controlled study to assess the efficacy and carry-over effect of repeated intra-articular injections of hyaluronic acid in knee osteoarthritis: the AMELIA project.

Navarro-Sarabia F, Coronel P, Collantes E, Navarro FJ, de la Serna AR, Naranjo A, Gimeno M, Herrero-Beaumont G; AMELIA study group..

Ann Rheum Dis. 2011 Nov;70(11):1957-62. doi: 10.1136/ard.2011.152017. Epub 2011 Aug 17.


Intra-articular hyaluronic acid increases cartilage breakdown biomarker in patients with knee osteoarthritis.

Gonzalez-Fuentes AM, Green DM, Rossen RD, Ng B.

Clin Rheumatol. 2010 Jun;29(6):619-24. doi: 10.1007/s10067-010-1376-8. Epub 2010 Jan 27.


Glucosamine sulfate and cartilage type II collagen degradation in patients with knee osteoarthritis: randomized discontinuation trial results employing biomarkers.

Cibere J, Thorne A, Kopec JA, Singer J, Canvin J, Robinson DB, Pope J, Hong P, Grant E, Lobanok T, Ionescu M, Poole AR, Esdaile JM.

J Rheumatol. 2005 May;32(5):896-902.


Uncoupling of type II collagen synthesis and degradation predicts progression of joint damage in patients with knee osteoarthritis.

Garnero P, Ayral X, Rousseau JC, Christgau S, Sandell LJ, Dougados M, Delmas PD.

Arthritis Rheum. 2002 Oct;46(10):2613-24.


Knee vs hip single-joint intra-articular hyaluronic acid injection in patients with both hip and knee osteoarthritis: a pilot study.

Diraçoğlu D, Alptekin K, Teksöz B, Yağci I, Ozçakar L, Aksoy C.

Clin Rheumatol. 2009 Sep;28(9):1021-4. doi: 10.1007/s10067-009-1199-7. Epub 2009 May 20.


[Efficacy and safety of a single intra-articular injection of 2% hyaluronic acid plus mannitol in knee osteoarthritis over a 6-month period].

Borrás-Verdera A, Calcedo-Bernal V, Ojeda-Levenfeld J, Clavel-Sainz C.

Rev Esp Cir Ortop Traumatol. 2012 Jul-Aug;56(4):274-80. doi: 10.1016/j.recot.2012.02.004. Epub 2012 Apr 19. Spanish.


Multicentre, prospective, open study to evaluate the safety and efficacy of hylan G-F 20 in knee osteoarthritis subjects presenting with pain following arthroscopic meniscectomy.

Huskin JP, Vandekerckhove B, Delincé P, Verdonk R, Dubuc JE, Willems S, Hardy P, Blanco FJ, Charrois O, Handelberg F.

Knee Surg Sports Traumatol Arthrosc. 2008 Aug;16(8):747-52. doi: 10.1007/s00167-008-0556-4. Epub 2008 Jun 7.


[The efficacy of low- and high-molecular-weight hyaluronic acid applications after arthroscopic debridement in patients with osteoarthritis of the knee].

Atay T, Aslan A, Baydar ML, Ceylan B, Baykal B, Kirdemir V.

Acta Orthop Traumatol Turc. 2008 Aug-Oct;42(4):228-33. Turkish.


Platelet-rich plasma intra-articular injection versus hyaluronic acid viscosupplementation as treatments for cartilage pathology: from early degeneration to osteoarthritis.

Kon E, Mandelbaum B, Buda R, Filardo G, Delcogliano M, Timoncini A, Fornasari PM, Giannini S, Marcacci M.

Arthroscopy. 2011 Nov;27(11):1490-501. doi: 10.1016/j.arthro.2011.05.011. Epub 2011 Aug 10.


Efficacy of intra-articular polynucleotides in the treatment of knee osteoarthritis: a randomized, double-blind clinical trial.

Vanelli R, Costa P, Rossi SM, Benazzo F.

Knee Surg Sports Traumatol Arthrosc. 2010 Jul;18(7):901-7. doi: 10.1007/s00167-009-1039-y. Epub 2010 Jan 29.


The effect of viscosupplementation on neuromuscular control of the knee in patients with osteoarthritis.

Diracoglu D, Vural M, Baskent A, Dikici F, Aksoy C.

J Back Musculoskelet Rehabil. 2009;22(1):1-9. doi: 10.3233/BMR-2009-0207.


Evaluation of long-term antinociceptive properties of stabilized hyaluronic acid preparation (NASHA) in an animal model of repetitive joint pain.

Boettger MK, Kümmel D, Harrison A, Schaible HG.

Arthritis Res Ther. 2011 Jul 7;13(4):R110. doi: 10.1186/ar3394.

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