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Items: 1 to 20 of 55

1.

The Molecular Chaperone GRP78/BiP in the Development of Chemoresistance: Mechanism and Possible Treatment.

Roller C, Maddalo D.

Front Pharmacol. 2013 Feb 11;4:10. doi: 10.3389/fphar.2013.00010.

2.

The expression of the endoplasmic reticulum stress sensor BiP/GRP78 predicts response to chemotherapy and determines the efficacy of proteasome inhibitors in diffuse large b-cell lymphoma.

Mozos A, Roué G, López-Guillermo A, Jares P, Campo E, Colomer D, Martinez A.

Am J Pathol. 2011 Nov;179(5):2601-10. doi: 10.1016/j.ajpath.2011.07.031.

3.

The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78.

Roué G, Pérez-Galán P, Mozos A, López-Guerra M, Xargay-Torrent S, Rosich L, Saborit-Villarroya I, Normant E, Campo E, Colomer D.

Blood. 2011 Jan 27;117(4):1270-9. doi: 10.1182/blood-2010-04-278853.

4.

Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development.

Dong D, Ni M, Li J, Xiong S, Ye W, Virrey JJ, Mao C, Ye R, Wang M, Pen L, Dubeau L, Groshen S, Hofman FM, Lee AS.

Cancer Res. 2008 Jan 15;68(2):498-505. doi: 10.1158/0008-5472.CAN-07-2950.

5.

Transcriptional repression of the prosurvival endoplasmic reticulum chaperone GRP78/BIP by E2F1.

Racek T, Buhlmann S, Rüst F, Knoll S, Alla V, Pützer BM.

J Biol Chem. 2008 Dec 5;283(49):34305-14. doi: 10.1074/jbc.M803925200.

6.

GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy.

Firczuk M, Gabrysiak M, Barankiewicz J, Domagala A, Nowis D, Kujawa M, Jankowska-Steifer E, Wachowska M, Glodkowska-Mrowka E, Korsak B, Winiarska M, Golab J.

Cell Death Dis. 2013 Jul 25;4:e741. doi: 10.1038/cddis.2013.265.

7.

Stress induction of GRP78/BiP and its role in cancer.

Li J, Lee AS.

Curr Mol Med. 2006 Feb;6(1):45-54. Review.

PMID:
16472112
8.

Down-regulation of the endoplasmic reticulum chaperone GRP78/BiP by vomitoxin (Deoxynivalenol).

Yang GH, Li S, Pestka JJ.

Toxicol Appl Pharmacol. 2000 Feb 1;162(3):207-17.

PMID:
10652249
9.

Overexpression of the 78-kDa glucose-regulated protein/immunoglobulin-binding protein (GRP78/BiP) inhibits tissue factor procoagulant activity.

Watson LM, Chan AK, Berry LR, Li J, Sood SK, Dickhout JG, Xu L, Werstuck GH, Bajzar L, Klamut HJ, Austin RC.

J Biol Chem. 2003 May 9;278(19):17438-47.

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12.

Expression of GRP78, Master Regulator of the Unfolded Protein Response, Increases Chemoresistance in Pancreatic Ductal Adenocarcinoma.

Gifford JB, Huang W, Zeleniak AE, Hindoyan A, Wu H, Donahue TR, Hill R.

Mol Cancer Ther. 2016 May;15(5):1043-52. doi: 10.1158/1535-7163.MCT-15-0774.

PMID:
26939701
13.

ADP-ribosylation of the molecular chaperone GRP78/BiP.

Ledford BE, Leno GH.

Mol Cell Biochem. 1994 Sep;138(1-2):141-8. Review.

PMID:
7898457
15.

Down-regulation of molecular chaperone 78-kd glucose-regulated protein/immunoglobulin-binding protein expression involved in enhancement of human RS cell mutability.

Hirano J, Kita K, Sugaya S, Ichimura Y, Yamamori H, Nakajima N, Suzuki N.

Pancreas. 2008 Jan;36(1):e7-14. doi: 10.1097/mpa.0b013e31814dadf5.

PMID:
18192872
16.

Measurement and modification of the expression level of the chaperone protein and signaling regulator GRP78/BiP in mammalian cells.

Chen WT, Lee AS.

Methods Enzymol. 2011;490:217-33. doi: 10.1016/B978-0-12-385114-7.00013-1.

PMID:
21266253
17.

Induction of cellular stress and chaperone activation in organotypic slice cultures of hippocampus.

Lacour P, Heimrich B, Pröls F.

J Neurosci Methods. 2007 Oct 15;166(1):24-31.

PMID:
17681378
19.

Cab45S inhibits the ER stress-induced IRE1-JNK pathway and apoptosis via GRP78/BiP.

Chen L, Xu S, Liu L, Wen X, Xu Y, Chen J, Teng J.

Cell Death Dis. 2014 May 8;5:e1219. doi: 10.1038/cddis.2014.193.

20.

GRP78 induction in cancer: therapeutic and prognostic implications.

Lee AS.

Cancer Res. 2007 Apr 15;67(8):3496-9. Review.

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