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Items: 1 to 20 of 104

1.

Molecular mechanisms involved in cochlear implantation trauma and the protection of hearing and auditory sensory cells by inhibition of c-Jun-N-terminal kinase signaling.

Eshraghi AA, Gupta C, Van De Water TR, Bohorquez JE, Garnham C, Bas E, Talamo VM.

Laryngoscope. 2013 Mar;123 Suppl 1:S1-14. doi: 10.1002/lary.23902. Epub 2013 Feb 4.

PMID:
23382052
2.

Mechanisms of programmed cell death signaling in hair cells and support cells post-electrode insertion trauma.

Eshraghi AA, Lang DM, Roell J, Van De Water TR, Garnham C, Rodrigues H, Guardiola M, Gupta C, Mittal J.

Acta Otolaryngol. 2015 Apr;135(4):328-34. doi: 10.3109/00016489.2015.1012276. Epub 2015 Mar 11.

PMID:
25761716
3.

D-JNKI-1 treatment prevents the progression of hearing loss in a model of cochlear implantation trauma.

Eshraghi AA, He J, Mou CH, Polak M, Zine A, Bonny C, Balkany TJ, Van De Water TR.

Otol Neurotol. 2006 Jun;27(4):504-11.

PMID:
16791042
4.

A novel organ of corti explant model for the study of cochlear implantation trauma.

Bas E, Gupta C, Van De Water TR.

Anat Rec (Hoboken). 2012 Nov;295(11):1944-56. doi: 10.1002/ar.22585. Epub 2012 Oct 8.

5.

Dexamethasone base conserves hearing from electrode trauma-induced hearing loss.

Vivero RJ, Joseph DE, Angeli S, He J, Chen S, Eshraghi AA, Balkany TJ, Van de Water TR.

Laryngoscope. 2008 Nov;118(11):2028-35. doi: 10.1097/MLG.0b013e31818173ec.

PMID:
18818553
6.

A peptide inhibitor of c-Jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss.

Wang J, Van De Water TR, Bonny C, de Ribaupierre F, Puel JL, Zine A.

J Neurosci. 2003 Sep 17;23(24):8596-607.

7.

Mechanisms of hearing loss from trauma and inflammation: otoprotective therapies from the laboratory to the clinic.

van de Water TR, Dinh CT, Vivero R, Hoosien G, Eshraghi AA, Balkany TJ.

Acta Otolaryngol. 2010 Mar;130(3):308-11. doi: 10.1080/00016480903124655. Review.

PMID:
19579145
8.

Electrode array-eluted dexamethasone protects against electrode insertion trauma induced hearing and hair cell losses, damage to neural elements, increases in impedance and fibrosis: A dose response study.

Bas E, Bohorquez J, Goncalves S, Perez E, Dinh CT, Garnham C, Hessler R, Eshraghi AA, Van De Water TR.

Hear Res. 2016 Jul;337:12-24. doi: 10.1016/j.heares.2016.02.003. Epub 2016 Feb 15.

PMID:
26892906
9.

Local dexamethasone therapy conserves hearing in an animal model of electrode insertion trauma-induced hearing loss.

Eshraghi AA, Adil E, He J, Graves R, Balkany TJ, Van De Water TR.

Otol Neurotol. 2007 Sep;28(6):842-9.

PMID:
17471110
10.

Conservation of hearing and protection of auditory hair cells against trauma-induced losses by local dexamethasone therapy: molecular and genetic mechanisms.

Van De Water TR, Abi Hachem RN, Dinh CT, Bas E, Haake SM, Hoosien G, Vivero R, Chan S, He J, Eshraghi AA, Angeli SI, Telischi FF, Balkany TJ.

Cochlear Implants Int. 2010 Jun;11 Suppl 1:42-55. doi: 10.1179/146701010X12671178390834.

PMID:
21756583
11.

A novel combination of drug therapy to protect residual hearing post cochlear implant surgery.

Eshraghi AA, Roell J, Shaikh N, Telischi FF, Bauer B, Guardiola M, Bas E, Van De Water T, Rivera I, Mittal J.

Acta Otolaryngol. 2016;136(4):420-4. doi: 10.3109/00016489.2015.1134809. Epub 2016 Feb 6.

PMID:
26854005
12.

Inhibition of the c-Jun N-terminal kinase-mediated mitochondrial cell death pathway restores auditory function in sound-exposed animals.

Wang J, Ruel J, Ladrech S, Bonny C, van de Water TR, Puel JL.

Mol Pharmacol. 2007 Mar;71(3):654-66. Epub 2006 Nov 28.

13.

Cochlear implantation trauma and noise-induced hearing loss: Apoptosis and therapeutic strategies.

Eshraghi AA, Van de Water TR.

Anat Rec A Discov Mol Cell Evol Biol. 2006 Apr;288(4):473-81. Review.

14.

Blocking c-Jun-N-terminal kinase signaling can prevent hearing loss induced by both electrode insertion trauma and neomycin ototoxicity.

Eshraghi AA, Wang J, Adil E, He J, Zine A, Bublik M, Bonny C, Puel JL, Balkany TJ, Van De Water TR.

Hear Res. 2007 Apr;226(1-2):168-77. Epub 2006 Nov 13.

PMID:
17098385
15.

Pattern of hearing loss in a rat model of cochlear implantation trauma.

Eshraghi AA, Polak M, He J, Telischi FF, Balkany TJ, Van De Water TR.

Otol Neurotol. 2005 May;26(3):442-7; discussion 447.

PMID:
15891647
16.

Mannitol protects hair cells against tumor necrosis factor α-induced loss.

Infante EB, Channer GA, Telischi FF, Gupta C, Dinh JT, Vu L, Eshraghi AA, Van De Water TR.

Otol Neurotol. 2012 Dec;33(9):1656-63. doi: 10.1097/MAO.0b013e31826bedd9.

PMID:
22996158
17.

AM-111 reduces hearing loss in a guinea pig model of acute labyrinthitis.

Barkdull GC, Hondarrague Y, Meyer T, Harris JP, Keithley EM.

Laryngoscope. 2007 Dec;117(12):2174-82. doi: 10.1097/MLG.0b013e3181461f92.

PMID:
18322422
18.

AM-111 protects against permanent hearing loss from impulse noise trauma.

Coleman JK, Littlesunday C, Jackson R, Meyer T.

Hear Res. 2007 Apr;226(1-2):70-8. Epub 2006 Jul 12.

PMID:
16839720
19.

Triamcinolone acetonide protects auditory hair cells from 4-hydroxy-2,3-nonenal (HNE) ototoxicity in vitro.

Guzman J, Ruiz J, Eshraghi AA, Polak M, Garnham C, Balkany TJ, Van de Water TR.

Acta Otolaryngol. 2006 Jul;126(7):685-90.

PMID:
16803705
20.

Biopolymer-released dexamethasone prevents tumor necrosis factor alpha-induced loss of auditory hair cells in vitro: implications toward the development of a drug-eluting cochlear implant electrode array.

Dinh C, Hoang K, Haake S, Chen S, Angeli S, Nong E, Eshraghi AA, Balkany TJ, Van De Water TR.

Otol Neurotol. 2008 Oct;29(7):1012-9. doi: 10.1097/MAO.0b013e3181859a1f.

PMID:
18818545

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