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Items: 1 to 20 of 100

1.

Amelioration of arthritis through mobilization of peptide-specific CD8+ regulatory T cells.

Leavenworth JW, Tang X, Kim HJ, Wang X, Cantor H.

J Clin Invest. 2013 Mar;123(3):1382-9. doi: 10.1172/JCI66938. Epub 2013 Feb 8.

2.

Regulation of CD8+ regulatory T cells: Interruption of the NKG2A-Qa-1 interaction allows robust suppressive activity and resolution of autoimmune disease.

Lu L, Kim HJ, Werneck MB, Cantor H.

Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19420-5. doi: 10.1073/pnas.0810383105. Epub 2008 Dec 1.

3.

HLA-E-restricted regulatory CD8(+) T cells are involved in development and control of human autoimmune type 1 diabetes.

Jiang H, Canfield SM, Gallagher MP, Jiang HH, Jiang Y, Zheng Z, Chess L.

J Clin Invest. 2010 Oct;120(10):3641-50. doi: 10.1172/JCI43522. Epub 2010 Sep 27.

4.

MHC Ib molecule Qa-1 presents Mycobacterium tuberculosis peptide antigens to CD8+ T cells and contributes to protection against infection.

Bian Y, Shang S, Siddiqui S, Zhao J, Joosten SA, Ottenhoff THM, Cantor H, Wang CR.

PLoS Pathog. 2017 May 5;13(5):e1006384. doi: 10.1371/journal.ppat.1006384. eCollection 2017 May.

5.

Physiological induction of regulatory Qa-1-restricted CD8+ T cells triggered by endogenous CD4+ T cell responses.

Varthaman A, Clement M, Khallou-Laschet J, Fornasa G, Gaston AT, Dussiot M, Caligiuri G, Cantor H, Kaveri S, Nicoletti A.

PLoS One. 2011;6(6):e21628. doi: 10.1371/journal.pone.0021628. Epub 2011 Jun 27.

6.

Differential requirement for tapasin in the presentation of leader- and insulin-derived peptide antigens to Qa-1b-restricted CTLs.

Li L, Sullivan BA, Aldrich CJ, Soloski MJ, Forman J, Grandea AG 3rd, Jensen PE, Van Kaer L.

J Immunol. 2004 Sep 15;173(6):3707-15.

7.

Disruption of CD8+ Treg activity results in expansion of T follicular helper cells and enhanced antitumor immunity.

Alvarez Arias DA, Kim HJ, Zhou P, Holderried TA, Wang X, Dranoff G, Cantor H.

Cancer Immunol Res. 2014 Mar;2(3):207-16. doi: 10.1158/2326-6066.CIR-13-0121. Epub 2013 Dec 31.

8.
9.

Peptide immunization indicates that CD8+ T cells are the dominant effector cells in trinitrophenyl-specific contact hypersensitivity.

Martin S, Lappin MB, Kohler J, Delattre V, Leicht C, Preckel T, Simon JC, Weltzien HU.

J Invest Dermatol. 2000 Aug;115(2):260-6.

10.

Genetic disruption of CD8+ Treg activity enhances the immune response to viral infection.

Holderried TA, Lang PA, Kim HJ, Cantor H.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21089-94. doi: 10.1073/pnas.1320999110. Epub 2013 Dec 9.

12.

Mucosal administration of an altered CII263-272 peptide inhibits collagen-induced arthritis by suppression of Th1/Th17 cells and expansion of regulatory T cells.

Zhao J, Li R, He J, Shi J, Long L, Li Z.

Rheumatol Int. 2008 Nov;29(1):9-16. doi: 10.1007/s00296-008-0634-4. Epub 2008 Jul 5.

PMID:
18600328
13.

A peptide from heat shock protein 60 is the dominant peptide bound to Qa-1 in the absence of the MHC class Ia leader sequence peptide Qdm.

Davies A, Kalb S, Liang B, Aldrich CJ, Lemonnier FA, Jiang H, Cotter R, Soloski MJ.

J Immunol. 2003 May 15;170(10):5027-33.

14.

Analysis of regulatory CD8 T cells in Qa-1-deficient mice.

Hu D, Ikizawa K, Lu L, Sanchirico ME, Shinohara ML, Cantor H.

Nat Immunol. 2004 May;5(5):516-23. Epub 2004 Apr 18.

PMID:
15098030
15.

Generation in vivo of peptide-specific cytotoxic T cells and presence of regulatory T cells during vaccination with hTERT (class I and II) peptide-pulsed DCs.

Aloysius MM, Mc Kechnie AJ, Robins RA, Verma C, Eremin JM, Farzaneh F, Habib NA, Bhalla J, Hardwick NR, Satthaporn S, Sreenivasan T, El-Sheemy M, Eremin O.

J Transl Med. 2009 Mar 19;7:18. doi: 10.1186/1479-5876-7-18.

16.

Suppression of autoimmune disease after vaccination with autoreactive T cells that express Qa-1 peptide complexes.

Panoutsakopoulou V, Huster KM, McCarty N, Feinberg E, Wang R, Wucherpfennig KW, Cantor H.

J Clin Invest. 2004 Apr;113(8):1218-24.

17.
18.

The immunoregulatory effects of Qa-1.

Lu L, Werneck MB, Cantor H.

Immunol Rev. 2006 Aug;212:51-9. Review.

PMID:
16903905
19.

MHC class II peptides induce CD8+CD44+Ly49+ regulatory T cells in C57BL/6 mice.

Yao Y, Wang X, Zhou H, Zhang H, Shi Y, Wang S, Wang X.

Cell Immunol. 2017 Feb;312:71-77. doi: 10.1016/j.cellimm.2016.11.005. Epub 2016 Nov 9.

PMID:
27847106
20.

APL-1, an altered peptide ligand derived from human heat-shock protein 60, selectively induces apoptosis in activated CD4+ CD25+ T cells from peripheral blood of rheumatoid arthritis patients.

Barberá A, Lorenzo N, Garrido G, Mazola Y, Falcón V, Torres AM, Hernández MI, Hernández MV, Margry B, de Groot AM, van Roon J, van der Zee R, Broere F, van Eden W, Padrón G, Domínguez Mdel C.

Int Immunopharmacol. 2013 Dec;17(4):1075-83. doi: 10.1016/j.intimp.2013.10.010. Epub 2013 Oct 29.

PMID:
24177275

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