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Items: 1 to 20 of 99

1.

Role for the obesity-related FTO gene in the cellular sensing of amino acids.

Gulati P, Cheung MK, Antrobus R, Church CD, Harding HP, Tung YC, Rimmington D, Ma M, Ron D, Lehner PJ, Ashcroft FM, Cox RD, Coll AP, O'Rahilly S, Yeo GS.

Proc Natl Acad Sci U S A. 2013 Feb 12;110(7):2557-62. doi: 10.1073/pnas.1222796110. Epub 2013 Jan 28.

2.

The role of the FTO (Fat Mass and Obesity Related) locus in regulating body size and composition.

Yeo GS.

Mol Cell Endocrinol. 2014 Nov;397(1-2):34-41. doi: 10.1016/j.mce.2014.09.012. Epub 2014 Sep 16. Review.

PMID:
25224490
3.

The 'Fat Mass and Obesity Related' (FTO) gene: Mechanisms of Impact on Obesity and Energy Balance.

Speakman JR.

Curr Obes Rep. 2015 Mar;4(1):73-91. doi: 10.1007/s13679-015-0143-1. Review.

PMID:
26627093
4.

Association of obesity with rs1421085 and rs9939609 polymorphisms of FTO gene.

Solak M, Ozdemir Erdogan M, Yildiz SH, Ucok K, Yuksel S, Arıkan Terzi ES, Bestepe A.

Mol Biol Rep. 2014 Nov;41(11):7381-6. doi: 10.1007/s11033-014-3627-2. Epub 2014 Jul 30.

PMID:
25074273
5.

Association of the FTO and ADRB2 genes with body composition and fat distribution in obese women.

Rauhio A, Uusi-Rasi K, Nikkari ST, Kannus P, Sievänen H, Kunnas T.

Maturitas. 2013 Oct;76(2):165-71. doi: 10.1016/j.maturitas.2013.07.004. Epub 2013 Aug 1.

PMID:
23911093
6.

The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice.

Gao X, Shin YH, Li M, Wang F, Tong Q, Zhang P.

PLoS One. 2010 Nov 16;5(11):e14005. doi: 10.1371/journal.pone.0014005.

7.

Determination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children.

Sällman Almén M, Rask-Andersen M, Jacobsson JA, Ameur A, Kalnina I, Moschonis G, Juhlin S, Bringeland N, Hedberg LA, Ignatovica V, Chrousos GP, Manios Y, Klovins J, Marcus C, Gyllensten U, Fredriksson R, Schiöth HB.

Int J Obes (Lond). 2013 Mar;37(3):424-31. doi: 10.1038/ijo.2012.57. Epub 2012 Apr 24.

8.

FTO expression is regulated by availability of essential amino acids.

Cheung MK, Gulati P, O'Rahilly S, Yeo GS.

Int J Obes (Lond). 2013 May;37(5):744-7. doi: 10.1038/ijo.2012.77. Epub 2012 May 22.

PMID:
22614055
9.

Prevalence of loss-of-function FTO mutations in lean and obese individuals.

Meyre D, Proulx K, Kawagoe-Takaki H, Vatin V, Gutiérrez-Aguilar R, Lyon D, Ma M, Choquet H, Horber F, Van Hul W, Van Gaal L, Balkau B, Visvikis-Siest S, Pattou F, Farooqi IS, Saudek V, O'Rahilly S, Froguel P, Sedgwick B, Yeo GS.

Diabetes. 2010 Jan;59(1):311-8. doi: 10.2337/db09-0703. Epub 2009 Oct 15.

10.

No association of obesity gene FTO with body composition at the age of 6 months. The Generation R Study.

Mook-Kanamori DO, Ay L, Hofman A, van Duijn CM, Moll HA, Raat H, Hokken-Koelega AC, Jaddoe VW.

J Endocrinol Invest. 2011 Jan;34(1):16-20. doi: 10.3275/7075. Epub 2010 May 28.

PMID:
20511725
11.

Obesity-associated variants within FTO form long-range functional connections with IRX3.

Smemo S, Tena JJ, Kim KH, Gamazon ER, Sakabe NJ, Gómez-Marín C, Aneas I, Credidio FL, Sobreira DR, Wasserman NF, Lee JH, Puviindran V, Tam D, Shen M, Son JE, Vakili NA, Sung HK, Naranjo S, Acemel RD, Manzanares M, Nagy A, Cox NJ, Hui CC, Gomez-Skarmeta JL, Nóbrega MA.

Nature. 2014 Mar 20;507(7492):371-5. doi: 10.1038/nature13138. Epub 2014 Mar 12.

12.

Several obesity- and nutrient-related gene polymorphisms but not FTO and UCP variants modulate postabsorptive resting energy expenditure and fat-induced thermogenesis in obese individuals: the NUGENOB study.

Goossens GH, Petersen L, Blaak EE, Hul G, Arner P, Astrup A, Froguel P, Patel K, Pedersen O, Polak J, Oppert JM, Martinez JA, Sørensen TI, Saris WH; NUGENOB Consortium..

Int J Obes (Lond). 2009 Jun;33(6):669-79. doi: 10.1038/ijo.2009.59. Epub 2009 Apr 28.

PMID:
19399022
13.

Fat mass and obesity-related (FTO) shuttles between the nucleus and cytoplasm.

Gulati P, Avezov E, Ma M, Antrobus R, Lehner P, O'Rahilly S, Yeo GS.

Biosci Rep. 2014 Oct 22;34(5). pii: e00144. doi: 10.1042/BSR20140111.

14.

Variation in the fat mass and obesity-related (FTO) genotype is not associated with body fatness in infants, but possibly with their length.

Henriksson P, Löf M, Söderkvist P, Forsum E.

Pediatr Obes. 2014 Oct;9(5):e112-5. doi: 10.1111/ijpo.231. Epub 2014 May 21.

PMID:
24846219
15.

The genetics of obesity: FTO leads the way.

Fawcett KA, Barroso I.

Trends Genet. 2010 Jun;26(6):266-74. doi: 10.1016/j.tig.2010.02.006. Epub 2010 Apr 8. Review.

16.

The biology of FTO: from nucleic acid demethylase to amino acid sensor.

Gulati P, Yeo GS.

Diabetologia. 2013 Oct;56(10):2113-21. doi: 10.1007/s00125-013-2999-5. Epub 2013 Jul 30. Review.

17.

Associations between a single nucleotide polymorphism of the FTO Gene (rs9939609) and obesity-related characteristics over time during puberty in a Dutch children cohort.

Rutters F, Nieuwenhuizen AG, Bouwman F, Mariman E, Westerterp-Plantenga MS.

J Clin Endocrinol Metab. 2011 Jun;96(6):E939-42. doi: 10.1210/jc.2010-2413. Epub 2011 Mar 16.

PMID:
21411553
18.

Detailed analysis of variants in FTO in association with body composition in a cohort of 70-year-olds suggests a weakened effect among elderly.

Jacobsson JA, Almén MS, Benedict C, Hedberg LA, Michaëlsson K, Brooks S, Kullberg J, Axelsson T, Johansson L, Ahlström H, Fredriksson R, Lind L, Schiöth HB.

PLoS One. 2011;6(5):e20158. doi: 10.1371/journal.pone.0020158. Epub 2011 May 27.

19.

FTO genotype and 2-year change in body composition and fat distribution in response to weight-loss diets: the POUNDS LOST Trial.

Zhang X, Qi Q, Zhang C, Smith SR, Hu FB, Sacks FM, Bray GA, Qi L.

Diabetes. 2012 Nov;61(11):3005-11. doi: 10.2337/db11-1799. Epub 2012 Aug 13. Erratum in: Diabetes. 2013 Feb;62(2):662. Smith, Steven R [added]; Bray, George A [added].

20.

Relation of fat-mass and obesity-associated gene polymorphism to fat mass content and body mass index in obese children.

Pyrzak B, Wisniewska A, Majcher A, Tysarowski A, Demkow U.

Adv Exp Med Biol. 2013;756:255-62. doi: 10.1007/978-94-007-4549-0_32.

PMID:
22836643

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