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Items: 1 to 20 of 125

1.

Association study of 25 type 2 diabetes related Loci with measures of obesity in Indian sib pairs.

Gupta V, Vinay DG, Sovio U, Rafiq S, Kranthi Kumar MV, Janipalli CS, Evans D, Mani KR, Sandeep MN, Taylor A, Kinra S, Sullivan R, Bowen L, Timpson N, Smith GD, Dudbridge F, Prabhakaran D, Ben-Shlomo Y, Reddy KS, Ebrahim S, Chandak GR; Indian Migration Study Group.

PLoS One. 2013;8(1):e53944. doi: 10.1371/journal.pone.0053944. Epub 2013 Jan 17.

2.

Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk.

Sanghera DK, Ortega L, Han S, Singh J, Ralhan SK, Wander GS, Mehra NK, Mulvihill JJ, Ferrell RE, Nath SK, Kamboh MI.

BMC Med Genet. 2008 Jul 3;9:59. doi: 10.1186/1471-2350-9-59.

3.

Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs.

Gupta V, Vinay DG, Rafiq S, Kranthikumar MV, Janipalli CS, Giambartolomei C, Evans DM, Mani KR, Sandeep MN, Taylor AE, Kinra S, Sullivan RM, Bowen L, Timpson NJ, Smith GD, Dudbridge F, Prabhakaran D, Ben-Shlomo Y, Reddy KS, Ebrahim S, Chandak GR; Indian Migration Study Group.

Diabetologia. 2012 Feb;55(2):349-57. doi: 10.1007/s00125-011-2355-6. Epub 2011 Nov 4.

4.

Association of type 2 diabetes susceptibility loci with one-year weight loss in the look AHEAD clinical trial.

Peter I, McCaffery JM, Kelley-Hedgepeth A, Hakonarson H, Reis S, Wagenknecht LE, Kopin AS, Huggins GS; Genetics Subgroup of the Look AHEAD Study.

Obesity (Silver Spring). 2012 Aug;20(8):1675-82. doi: 10.1038/oby.2012.11. Epub 2012 Feb 6.

5.

Replication and Relevance of Multiple Susceptibility Loci Discovered from Genome Wide Association Studies for Type 2 Diabetes in an Indian Population.

Phani NM, Adhikari P, Nagri SK, D'Souza SC, Satyamoorthy K, Rai PS.

PLoS One. 2016 Jun 16;11(6):e0157364. doi: 10.1371/journal.pone.0157364. eCollection 2016.

6.

CDKAL1 and HHEX are associated with type 2 diabetes-related traits among Yup'ik people.

Klimentidis YC, Lemas DJ, Wiener HH, O'Brien DM, Havel PJ, Stanhope KL, Hopkins SE, Tiwari HK, Boyer BB.

J Diabetes. 2014 May;6(3):251-9. doi: 10.1111/1753-0407.12093. Epub 2013 Oct 29.

7.

Loci of TCF7L2, HHEX and IDE on chromosome 10q and the susceptibility of their genetic polymorphisms to type 2 diabetes.

Nordman S, Ostenson CG, Efendic S, Gu HF.

Exp Clin Endocrinol Diabetes. 2009 Apr;117(4):186-90. doi: 10.1055/s-0028-1100419. Epub 2008 Dec 3.

PMID:
19053027
8.

A validation study of type 2 diabetes-related variants of the TCF7L2, HHEX, KCNJ11, and ADIPOQ genes in one endogamous ethnic group of north India.

Gupta V, Khadgawat R, Ng HK, Kumar S, Aggarwal A, Rao VR, Sachdeva MP.

Ann Hum Genet. 2010 Jul;74(4):361-8. doi: 10.1111/j.1469-1809.2010.00580.x.

9.

Contribution of 24 obesity-associated genetic variants to insulin resistance, pancreatic beta-cell function and type 2 diabetes risk in the French population.

Robiou-du-Pont S, Bonnefond A, Yengo L, Vaillant E, Lobbens S, Durand E, Weill J, Lantieri O, Balkau B, Charpentier G, Marre M, Froguel P, Meyre D.

Int J Obes (Lond). 2013 Jul;37(7):980-5. doi: 10.1038/ijo.2012.175. Epub 2012 Oct 23.

PMID:
23090577
10.

Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians.

Ng MC, Park KS, Oh B, Tam CH, Cho YM, Shin HD, Lam VK, Ma RC, So WY, Cho YS, Kim HL, Lee HK, Chan JC, Cho NH.

Diabetes. 2008 Aug;57(8):2226-33. doi: 10.2337/db07-1583. Epub 2008 May 9.

11.

Genetic variants associated with lean and obese type 2 diabetes in a Han Chinese population: A case-control study.

Kong X, Xing X, Hong J, Zhang X, Yang W.

Medicine (Baltimore). 2016 Jun;95(23):e3841. doi: 10.1097/MD.0000000000003841.

12.

Association of indices of liver and adipocyte insulin resistance with 19 confirmed susceptibility loci for type 2 diabetes in 6,733 non-diabetic Finnish men.

Vangipurapu J, Stančáková A, Pihlajamäki J, Kuulasmaa TM, Kuulasmaa T, Paananen J, Kuusisto J, Ferrannini E, Laakso M.

Diabetologia. 2011 Mar;54(3):563-71. doi: 10.1007/s00125-010-1977-4. Epub 2010 Dec 12.

PMID:
21153532
13.

The Association of Type 2 Diabetes Loci Identified in Genome-Wide Association Studies with Metabolic Syndrome and Its Components in a Chinese Population with Type 2 Diabetes.

Kong X, Zhang X, Xing X, Zhang B, Hong J, Yang W.

PLoS One. 2015 Nov 24;10(11):e0143607. doi: 10.1371/journal.pone.0143607. eCollection 2015.

14.

Replication of genetic variants from genome-wide association studies with metabolic traits in an island population of the Adriatic coast of Croatia.

Karns R, Zhang G, Jeran N, Havas-Augustin D, Missoni S, Niu W, Indugula SR, Sun G, Durakovic Z, Narancic NS, Rudan P, Chakraborty R, Deka R.

Eur J Hum Genet. 2011 Mar;19(3):341-6. doi: 10.1038/ejhg.2010.178. Epub 2010 Dec 8.

15.

The effect of FOXA2 rs1209523 on glucose-related phenotypes and risk of type 2 diabetes in Danish individuals.

Banasik K, Hollensted M, Andersson E, Sparsø T, Sandbaek A, Lauritzen T, Jørgensen T, Witte DR, Pedersen O, Hansen T.

BMC Med Genet. 2012 Feb 12;13:10. doi: 10.1186/1471-2350-13-10.

16.

TCF7L2 is associated with type 2 diabetes in nonobese individuals from Tunisia.

Bouhaha R, Choquet H, Meyre D, Abid Kamoun H, Ennafaa H, Baroudi T, Sassi R, Vaxillaire M, Elgaaied A, Froguel P, Cauchi S.

Pathol Biol (Paris). 2010 Dec;58(6):426-9. doi: 10.1016/j.patbio.2009.01.003. Epub 2009 Mar 14.

PMID:
19286335
17.

Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independent of obesity.

Scott RA, Fall T, Pasko D, Barker A, Sharp SJ, Arriola L, Balkau B, Barricarte A, Barroso I, Boeing H, Clavel-Chapelon F, Crowe FL, Dekker JM, Fagherazzi G, Ferrannini E, Forouhi NG, Franks PW, Gavrila D, Giedraitis V, Grioni S, Groop LC, Kaaks R, Key TJ, Kühn T, Lotta LA, Nilsson PM, Overvad K, Palli D, Panico S, Quirós JR, Rolandsson O, Roswall N, Sacerdote C, Sala N, Sánchez MJ, Schulze MB, Siddiq A, Slimani N, Sluijs I, Spijkerman AM, Tjonneland A, Tumino R, van der A DL, Yaghootkar H; RISC study group; EPIC-InterAct consortium, McCarthy MI, Semple RK, Riboli E, Walker M, Ingelsson E, Frayling TM, Savage DB, Langenberg C, Wareham NJ.

Diabetes. 2014 Dec;63(12):4378-4387. doi: 10.2337/db14-0319. Epub 2014 Jun 19.

18.

Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population.

Horikoshi M, Hara K, Ito C, Shojima N, Nagai R, Ueki K, Froguel P, Kadowaki T.

Diabetologia. 2007 Dec;50(12):2461-6. Epub 2007 Oct 10.

PMID:
17928989
19.

Replication of association between a common variant near melanocortin-4 receptor gene and obesity-related traits in Asian Sikhs.

Been LF, Nath SK, Ralhan SK, Wander GS, Mehra NK, Singh J, Mulvihill JJ, Sanghera DK.

Obesity (Silver Spring). 2010 Feb;18(2):425-9. doi: 10.1038/oby.2009.254. Epub 2009 Aug 13.

20.

The type 2 diabetes-associated variant in TCF7L2 is associated with latent autoimmune diabetes in adult Europeans and the gene effect is modified by obesity: a meta-analysis and an individual study.

Lukacs K, Hosszufalusi N, Dinya E, Bakacs M, Madacsy L, Panczel P.

Diabetologia. 2012 Mar;55(3):689-93. doi: 10.1007/s00125-011-2378-z. Epub 2011 Nov 23.

PMID:
22109281

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