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Items: 1 to 20 of 91

1.

A Drosophila model of high sugar diet-induced cardiomyopathy.

Na J, Musselman LP, Pendse J, Baranski TJ, Bodmer R, Ocorr K, Cagan R.

PLoS Genet. 2013;9(1):e1003175. doi: 10.1371/journal.pgen.1003175. Epub 2013 Jan 10.

2.

High-sugar intake does not exacerbate metabolic abnormalities or cardiac dysfunction in genetic cardiomyopathy.

Hecker PA, Galvao TF, O'Shea KM, Brown BH, Henderson R Jr, Riggle H, Gupte SA, Stanley WC.

Nutrition. 2012 May;28(5):520-6. doi: 10.1016/j.nut.2011.09.017. Epub 2012 Feb 2.

3.

Insulin stimulates translocation of human GLUT4 to the membrane in fat bodies of transgenic Drosophila melanogaster.

Crivat G, Lizunov VA, Li CR, Stenkula KG, Zimmerberg J, Cushman SW, Pick L.

PLoS One. 2013 Nov 6;8(11):e77953. doi: 10.1371/journal.pone.0077953. eCollection 2013.

4.

Changes in the expression of the Alzheimer’s disease-associated presenilin gene in drosophila heart leads to cardiac dysfunction.

Li A, Zhou C, Moore J, Zhang P, Tsai TH, Lee HC, Romano DM, McKee ML, Schoenfeld DA, Serra MJ, Raygor K, Cantiello HF, Fujimoto JG, Tanzi RE.

Curr Alzheimer Res. 2011 May;8(3):313-22.

5.

High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in Drosophila.

Birse RT, Choi J, Reardon K, Rodriguez J, Graham S, Diop S, Ocorr K, Bodmer R, Oldham S.

Cell Metab. 2010 Nov 3;12(5):533-44. doi: 10.1016/j.cmet.2010.09.014.

6.

Huntington's disease induced cardiac amyloidosis is reversed by modulating protein folding and oxidative stress pathways in the Drosophila heart.

Melkani GC, Trujillo AS, Ramos R, Bodmer R, Bernstein SI, Ocorr K.

PLoS Genet. 2013;9(12):e1004024. doi: 10.1371/journal.pgen.1004024. Epub 2013 Dec 19.

7.

Increased hexosamine pathway flux and high fat feeding are not additive in inducing insulin resistance: evidence for a shared pathway.

Cooksey RC, McClain DA.

Amino Acids. 2011 Mar;40(3):841-6. doi: 10.1007/s00726-010-0701-5. Epub 2010 Jul 24.

8.
9.

The UNC-45 chaperone is critical for establishing myosin-based myofibrillar organization and cardiac contractility in the Drosophila heart model.

Melkani GC, Bodmer R, Ocorr K, Bernstein SI.

PLoS One. 2011;6(7):e22579. doi: 10.1371/journal.pone.0022579. Epub 2011 Jul 25.

10.

Transformed Drosophila cells evade diet-mediated insulin resistance through wingless signaling.

Hirabayashi S, Baranski TJ, Cagan RL.

Cell. 2013 Aug 1;154(3):664-75. doi: 10.1016/j.cell.2013.06.030.

11.

Impairment of cardiac insulin signaling and myocardial contractile performance in high-cholesterol/fructose-fed rats.

Deng JY, Huang JP, Lu LS, Hung LM.

Am J Physiol Heart Circ Physiol. 2007 Aug;293(2):H978-87. Epub 2007 Mar 30.

12.

Insulin signaling regulates cardiac titin properties in heart development and diabetic cardiomyopathy.

Krüger M, Babicz K, von Frieling-Salewsky M, Linke WA.

J Mol Cell Cardiol. 2010 May;48(5):910-6. doi: 10.1016/j.yjmcc.2010.02.012. Epub 2010 Feb 23.

PMID:
20184888
13.

Myocardial insulin resistance induced by high fat feeding in heart failure is associated with preserved contractile function.

Christopher BA, Huang HM, Berthiaume JM, McElfresh TA, Chen X, Croniger CM, Muzic RF Jr, Chandler MP.

Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1917-27. doi: 10.1152/ajpheart.00687.2010. Epub 2010 Sep 17.

14.

Interplay between heart and skeletal muscle disease in heart failure: the 2011 George E. Brown Memorial Lecture.

McNally EM, Goldstein JA.

Circ Res. 2012 Mar 2;110(5):749-54. doi: 10.1161/CIRCRESAHA.111.256776.

15.

MicroRNA Expression Signature Is Altered in the Cardiac Remodeling Induced by High Fat Diets.

Guedes EC, França GS, Lino CA, Koyama FC, Moreira Ldo N, Alexandre JG, Barreto-Chaves ML, Galante PA, Diniz GP.

J Cell Physiol. 2016 Aug;231(8):1771-83. doi: 10.1002/jcp.25280. Epub 2015 Dec 30.

PMID:
26638879
16.

Dipeptidyl peptidase inhibition prevents diastolic dysfunction and reduces myocardial fibrosis in a mouse model of Western diet induced obesity.

Bostick B, Habibi J, Ma L, Aroor A, Rehmer N, Hayden MR, Sowers JR.

Metabolism. 2014 Aug;63(8):1000-11. doi: 10.1016/j.metabol.2014.04.002. Epub 2014 Apr 12.

17.

Lipotoxicity and cardiac dysfunction in mammals and Drosophila.

Birse RT, Bodmer R.

Crit Rev Biochem Mol Biol. 2011 Oct;46(5):376-85. doi: 10.3109/10409238.2011.599830. Epub 2011 Aug 19. Review.

18.

Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice.

Battiprolu PK, Hojayev B, Jiang N, Wang ZV, Luo X, Iglewski M, Shelton JM, Gerard RD, Rothermel BA, Gillette TG, Lavandero S, Hill JA.

J Clin Invest. 2012 Mar;122(3):1109-18. doi: 10.1172/JCI60329. Epub 2012 Feb 13.

19.

Drosophila as a model for the identification of genes causing adult human heart disease.

Wolf MJ, Amrein H, Izatt JA, Choma MA, Reedy MC, Rockman HA.

Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1394-9. Epub 2006 Jan 23.

20.

Probing the polygenic basis of cardiomyopathies in Drosophila.

Qian L, Bodmer R.

J Cell Mol Med. 2012 May;16(5):972-7. doi: 10.1111/j.1582-4934.2012.01529.x. Review.

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