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Items: 1 to 20 of 120

1.

Phosphorylation and ubiquitination-dependent degradation of CABIN1 releases p53 for transactivation upon genotoxic stress.

Choi SY, Jang H, Roe JS, Kim ST, Cho EJ, Youn HD.

Nucleic Acids Res. 2013 Feb 1;41(4):2180-90. doi: 10.1093/nar/gks1319. Epub 2013 Jan 8.

2.

ATM activates p53 by regulating MDM2 oligomerization and E3 processivity.

Cheng Q, Chen L, Li Z, Lane WS, Chen J.

EMBO J. 2009 Dec 16;28(24):3857-67. doi: 10.1038/emboj.2009.294.

3.

ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.

Chen L, Gilkes DM, Pan Y, Lane WS, Chen J.

EMBO J. 2005 Oct 5;24(19):3411-22. Epub 2005 Sep 15.

4.

A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.

Hinz M, Stilmann M, Arslan SÇ, Khanna KK, Dittmar G, Scheidereit C.

Mol Cell. 2010 Oct 8;40(1):63-74. doi: 10.1016/j.molcel.2010.09.008.

5.

ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage.

Dornan D, Shimizu H, Mah A, Dudhela T, Eby M, O'rourke K, Seshagiri S, Dixit VM.

Science. 2006 Aug 25;313(5790):1122-6.

6.

Mechanism of p53 stabilization by ATM after DNA damage.

Cheng Q, Chen J.

Cell Cycle. 2010 Feb 1;9(3):472-8.

7.

ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress.

Wu ZH, Wong ET, Shi Y, Niu J, Chen Z, Miyamoto S, Tergaonkar V.

Mol Cell. 2010 Oct 8;40(1):75-86. doi: 10.1016/j.molcel.2010.09.010.

8.

DNA damage-induced activation of ATM promotes β-TRCP-mediated Mdm2 ubiquitination and destruction.

Wang Z, Inuzuka H, Zhong J, Fukushima H, Wan L, Liu P, Wei W.

Oncotarget. 2012 Sep;3(9):1026-35.

9.

Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR.

Winter M, Sombroek D, Dauth I, Moehlenbrink J, Scheuermann K, Crone J, Hofmann TG.

Nat Cell Biol. 2008 Jul;10(7):812-24. doi: 10.1038/ncb1743. Epub 2008 Jun 8.

PMID:
18536714
10.

Phosphorylation of Daxx by ATM contributes to DNA damage-induced p53 activation.

Tang J, Agrawal T, Cheng Q, Qu L, Brewer MD, Chen J, Yang X.

PLoS One. 2013;8(2):e55813. doi: 10.1371/journal.pone.0055813. Epub 2013 Feb 6. Erratum in: PLoS One. 2013;8(9). doi:10.1371/annotation/032b026d-5bcf-4c1b-aa15-65c226a53818.

11.

Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage.

Pereg Y, Shkedy D, de Graaf P, Meulmeester E, Edelson-Averbukh M, Salek M, Biton S, Teunisse AF, Lehmann WD, Jochemsen AG, Shiloh Y.

Proc Natl Acad Sci U S A. 2005 Apr 5;102(14):5056-61. Epub 2005 Mar 23.

12.

hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress.

Gehen SC, Staversky RJ, Bambara RA, Keng PC, O'Reilly MA.

Oncogene. 2008 Jul 3;27(29):4065-74. doi: 10.1038/onc.2008.48. Epub 2008 Mar 10.

13.

Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.

Lossaint G, Besnard E, Fisher D, Piette J, Dulić V.

Oncogene. 2011 Oct 13;30(41):4261-74. doi: 10.1038/onc.2011.135. Epub 2011 May 2.

PMID:
21532626
14.

The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis.

Hao Z, Duncan GS, Su YW, Li WY, Silvester J, Hong C, You H, Brenner D, Gorrini C, Haight J, Wakeham A, You-Ten A, McCracken S, Elia A, Li Q, Detmar J, Jurisicova A, Hobeika E, Reth M, Sheng Y, Lang PA, Ohashi PS, Zhong Q, Wang X, Mak TW.

J Exp Med. 2012 Jan 16;209(1):173-86. doi: 10.1084/jem.20111363. Epub 2012 Jan 2.

15.
16.

BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage.

Fabbro M, Savage K, Hobson K, Deans AJ, Powell SN, McArthur GA, Khanna KK.

J Biol Chem. 2004 Jul 23;279(30):31251-8. Epub 2004 May 24.

17.

EDD inhibits ATM-mediated phosphorylation of p53.

Ling S, Lin WC.

J Biol Chem. 2011 Apr 29;286(17):14972-82. doi: 10.1074/jbc.M110.182527. Epub 2011 Mar 7.

18.

Role of autophagy in chemoresistance: regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA-PKcs and PARP-1.

Yoon JH, Ahn SG, Lee BH, Jung SH, Oh SH.

Biochem Pharmacol. 2012 Mar 15;83(6):747-57. doi: 10.1016/j.bcp.2011.12.029. Epub 2011 Dec 29.

PMID:
22226932
19.

Phosphorylation of PNKP by ATM prevents its proteasomal degradation and enhances resistance to oxidative stress.

Parsons JL, Khoronenkova SV, Dianova II, Ternette N, Kessler BM, Datta PK, Dianov GL.

Nucleic Acids Res. 2012 Dec;40(22):11404-15. doi: 10.1093/nar/gks909. Epub 2012 Oct 5.

20.

Inhibition of the ATM/p53 signal transduction pathway by Kaposi's sarcoma-associated herpesvirus interferon regulatory factor 1.

Shin YC, Nakamura H, Liang X, Feng P, Chang H, Kowalik TF, Jung JU.

J Virol. 2006 Mar;80(5):2257-66.

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