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Items: 1 to 20 of 76

1.

Identification of the N-terminal domain of the influenza virus PA responsible for the suppression of host protein synthesis.

Desmet EA, Bussey KA, Stone R, Takimoto T.

J Virol. 2013 Mar;87(6):3108-18. doi: 10.1128/JVI.02826-12. Epub 2013 Jan 2.

2.

Influenza A Virus Protein PA-X Contributes to Viral Growth and Suppression of the Host Antiviral and Immune Responses.

Hayashi T, MacDonald LA, Takimoto T.

J Virol. 2015 Jun;89(12):6442-52. doi: 10.1128/JVI.00319-15. Epub 2015 Apr 8.

3.

Critical Role of the PA-X C-Terminal Domain of Influenza A Virus in Its Subcellular Localization and Shutoff Activity.

Hayashi T, Chaimayo C, McGuinness J, Takimoto T.

J Virol. 2016 Jul 27;90(16):7131-41. doi: 10.1128/JVI.00954-16. Print 2016 Aug 15.

4.

Mapping of a Region of the PA-X Protein of Influenza A Virus That Is Important for Its Shutoff Activity.

Oishi K, Yamayoshi S, Kawaoka Y.

J Virol. 2015 Aug;89(16):8661-5. doi: 10.1128/JVI.01132-15. Epub 2015 Jun 3.

5.

PA-X is a virulence factor in avian H9N2 influenza virus.

Gao H, Xu G, Sun Y, Qi L, Wang J, Kong W, Sun H, Pu J, Chang KC, Liu J.

J Gen Virol. 2015 Sep;96(9):2587-94. doi: 10.1099/jgv.0.000232. Epub 2015 Jul 9.

PMID:
26296365
6.

Effects of influenza A virus NS1 protein on protein expression: the NS1 protein enhances translation and is not required for shutoff of host protein synthesis.

Salvatore M, Basler CF, Parisien JP, Horvath CM, Bourmakina S, Zheng H, Muster T, Palese P, García-Sastre A.

J Virol. 2002 Feb;76(3):1206-12.

7.

Comparing the functions of equine and canine influenza H3N8 virus PA-X proteins: Suppression of reporter gene expression and modulation of global host gene expression.

Feng KH, Sun M, Iketani S, Holmes EC, Parrish CR.

Virology. 2016 Sep;496:138-146. doi: 10.1016/j.virol.2016.06.001. Epub 2016 Jun 14.

8.

Non structural protein of avian influenza A (H11N1) virus is a weaker suppressor of immune responses but capable of inducing apoptosis in host cells.

Mukherjee S, Majumdar S, Vipat VC, Mishra AC, Chakrabarti AK.

Virol J. 2012 Aug 6;9:149. doi: 10.1186/1743-422X-9-149.

9.

Selective Degradation of Host RNA Polymerase II Transcripts by Influenza A Virus PA-X Host Shutoff Protein.

Khaperskyy DA, Schmaling S, Larkins-Ford J, McCormick C, Gaglia MM.

PLoS Pathog. 2016 Feb 5;12(2):e1005427. doi: 10.1371/journal.ppat.1005427. eCollection 2016 Feb.

10.

Synergism of co-mutation of two amino acid residues in NS1 protein increases the pathogenicity of influenza virus in mice.

Pu J, Wang J, Zhang Y, Fu G, Bi Y, Sun Y, Liu J.

Virus Res. 2010 Aug;151(2):200-4. doi: 10.1016/j.virusres.2010.05.007. Epub 2010 May 28.

PMID:
20546807
11.

Timing Is Everything: Coordinated Control of Host Shutoff by Influenza A Virus NS1 and PA-X Proteins.

Khaperskyy DA, McCormick C.

J Virol. 2015 Jul;89(13):6528-31. doi: 10.1128/JVI.00386-15. Epub 2015 Apr 15. Review.

12.

Avian and 1918 Spanish influenza a virus NS1 proteins bind to Crk/CrkL Src homology 3 domains to activate host cell signaling.

Heikkinen LS, Kazlauskas A, Melén K, Wagner R, Ziegler T, Julkunen I, Saksela K.

J Biol Chem. 2008 Feb 29;283(9):5719-27. doi: 10.1074/jbc.M707195200. Epub 2007 Dec 28.

13.

The novel influenza A virus protein PA-X and its naturally deleted variant show different enzymatic properties in comparison to the viral endonuclease PA.

Bavagnoli L, Cucuzza S, Campanini G, Rovida F, Paolucci S, Baldanti F, Maga G.

Nucleic Acids Res. 2015 Oct 30;43(19):9405-17. doi: 10.1093/nar/gkv926. Epub 2015 Sep 17.

14.

A new influenza virus virulence determinant: the NS1 protein four C-terminal residues modulate pathogenicity.

Jackson D, Hossain MJ, Hickman D, Perez DR, Lamb RA.

Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4381-6. doi: 10.1073/pnas.0800482105. Epub 2008 Mar 11.

15.

Specific residues of PB2 and PA influenza virus polymerase subunits confer the ability for RNA polymerase II degradation and virus pathogenicity in mice.

Llompart CM, Nieto A, Rodriguez-Frandsen A.

J Virol. 2014 Mar;88(6):3455-63. doi: 10.1128/JVI.02263-13. Epub 2014 Jan 8.

16.

Analysis of the PDZ binding specificities of Influenza A virus NS1 proteins.

Thomas M, Kranjec C, Nagasaka K, Matlashewski G, Banks L.

Virol J. 2011 Jan 19;8:25. doi: 10.1186/1743-422X-8-25.

17.

Alleles A and B of non-structural protein 1 of avian influenza A viruses differentially inhibit beta interferon production in human and mink lung cells.

Munir M, Zohari S, Metreveli G, Baule C, Belák S, Berg M.

J Gen Virol. 2011 Sep;92(Pt 9):2111-21. doi: 10.1099/vir.0.031716-0. Epub 2011 Jun 1.

PMID:
21632557
18.

Targeting of the influenza A virus polymerase PB1-PB2 interface indicates strain-specific assembly differences.

Reuther P, Mänz B, Brunotte L, Schwemmle M, Wunderlich K.

J Virol. 2011 Dec;85(24):13298-309. doi: 10.1128/JVI.00868-11. Epub 2011 Sep 28.

19.

Ribosomal frameshifting used in influenza A virus expression occurs within the sequence UCC_UUU_CGU and is in the +1 direction.

Firth AE, Jagger BW, Wise HM, Nelson CC, Parsawar K, Wills NM, Napthine S, Taubenberger JK, Digard P, Atkins JF.

Open Biol. 2012 Oct;2(10):120109. doi: 10.1098/rsob.120109.

20.

Differential effects of NS1 proteins of human pandemic H1N1/2009, avian highly pathogenic H5N1, and low pathogenic H5N2 influenza A viruses on cellular pre-mRNA polyadenylation and mRNA translation.

Kainov DE, Müller KH, Theisen LL, Anastasina M, Kaloinen M, Muller CP.

J Biol Chem. 2011 Mar 4;286(9):7239-47. doi: 10.1074/jbc.M110.203489. Epub 2010 Dec 16.

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