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Epidermal growth factor receptor expression and signaling are essential in glutamine's cytoprotective mechanism in heat-stressed intestinal epithelial-6 cells.

Niederlechner S, Baird C, Petrie B, Wischmeyer E, Wischmeyer PE.

Am J Physiol Gastrointest Liver Physiol. 2013 Mar 1;304(5):G543-52. doi: 10.1152/ajpgi.00418.2012. Epub 2012 Dec 28.


Fibronectin-integrin signaling is required for L-glutamine's protection against gut injury.

Niederlechner S, Klawitter J, Baird C, Kallweit AR, Christians U, Wischmeyer PE.

PLoS One. 2012;7(11):e50185. doi: 10.1371/journal.pone.0050185. Epub 2012 Nov 20.


Periodic Mechanical Stress Activates PKCĪ“-Dependent EGFR Mitogenic Signals in Rat Chondrocytes via PI3K-Akt and ERK1/2.

He P, Shen N, Gao G, Jiang X, Sun H, Zhou D, Xu N, Nong L, Ren K.

Cell Physiol Biochem. 2016;39(4):1281-94. doi: 10.1159/000447833. Epub 2016 Sep 8.


Epidermal growth factor receptor transactivation is required for proteinase-activated receptor-2-induced COX-2 expression in intestinal epithelial cells.

Hirota CL, Moreau F, Iablokov V, Dicay M, Renaux B, Hollenberg MD, MacNaughton WK.

Am J Physiol Gastrointest Liver Physiol. 2012 Jul;303(1):G111-9. doi: 10.1152/ajpgi.00358.2011. Epub 2012 Apr 19.


Apoptosis induced by depsipeptide FK228 coincides with inhibition of survival signaling in lung cancer cells.

Yu XD, Wang SY, Chen GA, Hou CM, Zhao M, Hong JA, Nguyen DM, Schrump DS.

Cancer J. 2007 Mar-Apr;13(2):105-13.


Role of EGFR transactivation in preventing apoptosis in Pseudomonas aeruginosa-infected human corneal epithelial cells.

Zhang J, Li H, Wang J, Dong Z, Mian S, Yu FS.

Invest Ophthalmol Vis Sci. 2004 Aug;45(8):2569-76.


Mechanisms of kringle fragment of urokinase-induced vascular smooth muscle cell migration.

Roztocil E, Nicholl SM, Davies MG.

J Surg Res. 2007 Jul;141(1):83-90.


HGF protects corneal epithelial cells from apoptosis by the PI-3K/Akt-1/Bad- but not the ERK1/2-mediated signaling pathway.

Kakazu A, Chandrasekher G, Bazan HE.

Invest Ophthalmol Vis Sci. 2004 Oct;45(10):3485-92.


Glutamine deprivation alters intestinal tight junctions via a PI3-K/Akt mediated pathway in Caco-2 cells.

Li N, Neu J.

J Nutr. 2009 Apr;139(4):710-4. doi: 10.3945/jn.108.101485. Epub 2009 Feb 11.


Dual inhibition of focal adhesion kinase and epidermal growth factor receptor pathways cooperatively induces death receptor-mediated apoptosis in human breast cancer cells.

Golubovskaya V, Beviglia L, Xu LH, Earp HS 3rd, Craven R, Cance W.

J Biol Chem. 2002 Oct 11;277(41):38978-87. Epub 2002 Aug 7.


Opposite regulation by PI3K/Akt and MAPK/ERK pathways of tissue factor expression, cell-associated procoagulant activity and invasiveness in MDA-MB-231 cells.

Hu C, Huang L, Gest C, Xi X, Janin A, Soria C, Li H, Lu H.

J Hematol Oncol. 2012 Jul 11;5:16. doi: 10.1186/1756-8722-5-16.


Interleukin-11 antagonizes Fas ligand-mediated apoptosis in IEC-18 intestinal epithelial crypt cells: role of MEK and Akt-dependent signaling.

Naugler KM, Baer KA, Ropeleski MJ.

Am J Physiol Gastrointest Liver Physiol. 2008 Mar;294(3):G728-37. doi: 10.1152/ajpgi.00002.2007. Epub 2008 Jan 17.


Bradykinin-induced p42/p44 MAPK phosphorylation and cell proliferation via Src, EGF receptors, and PI3-K/Akt in vascular smooth muscle cells.

Yang CM, Lin MI, Hsieh HL, Sun CC, Ma YH, Hsiao LD.

J Cell Physiol. 2005 Jun;203(3):538-46.


Concomitant inactivation of the epidermal growth factor receptor, phosphatidylinositol 3-kinase/Akt and Janus tyrosine kinase 2/signal transducer and activator of transcription 3 signalling pathways in cardiotoxin III-treated A549 cells.

Su JC, Lin KL, Chien CM, Chuang PW, Chang LS, Lin SR.

Clin Exp Pharmacol Physiol. 2010 Aug;37(8):833-40. doi: 10.1111/j.1440-1681.2010.05397.x. Epub 2010 Apr 26.


Glutamine prevents apoptosis in intestinal epithelial cells and induces differential protective pathways in heat and oxidant injury models.

Kallweit AR, Baird CH, Stutzman DK, Wischmeyer PE.

JPEN J Parenter Enteral Nutr. 2012 Sep;36(5):551-5. doi: 10.1177/0148607112445579. Epub 2012 Apr 27.


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