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Items: 1 to 20 of 100

1.

Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin.

Larkin A, Siddens LK, Krueger SK, Tilton SC, Waters KM, Williams DE, Baird WM.

Toxicol Appl Pharmacol. 2013 Mar 1;267(2):192-9. doi: 10.1016/j.taap.2012.12.011. Epub 2012 Dec 27.

2.

Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse.

Siddens LK, Bunde KL, Harper TA Jr, McQuistan TJ, Löhr CV, Bramer LM, Waters KM, Tilton SC, Krueger SK, Williams DE, Baird WM.

Toxicol Appl Pharmacol. 2015 Sep 1;287(2):149-60. doi: 10.1016/j.taap.2015.05.019. Epub 2015 Jun 3.

3.

The influence of diesel exhaust on polycyclic aromatic hydrocarbon-induced DNA damage, gene expression, and tumor initiation in Sencar mice in vivo.

Courter LA, Luch A, Musafia-Jeknic T, Arlt VM, Fischer K, Bildfell R, Pereira C, Phillips DH, Poirier MC, Baird WM.

Cancer Lett. 2008 Jun 28;265(1):135-47. doi: 10.1016/j.canlet.2008.02.017. Epub 2008 Mar 18.

4.

Polycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse.

Siddens LK, Larkin A, Krueger SK, Bradfield CA, Waters KM, Tilton SC, Pereira CB, Löhr CV, Arlt VM, Phillips DH, Williams DE, Baird WM.

Toxicol Appl Pharmacol. 2012 Nov 1;264(3):377-86. doi: 10.1016/j.taap.2012.08.014. Epub 2012 Aug 23.

5.
6.

Urban dust particulate matter alters PAH-induced carcinogenesis by inhibition of CYP1A1 and CYP1B1.

Courter LA, Musafia-Jeknic T, Fischer K, Bildfell R, Giovanini J, Pereira C, Baird WM.

Toxicol Sci. 2007 Jan;95(1):63-73. Epub 2006 Oct 23.

PMID:
17060372
7.

Role of cytochrome p4501 family members in the metabolic activation of polycyclic aromatic hydrocarbons in mouse epidermis.

Kleiner HE, Vulimiri SV, Hatten WB, Reed MJ, Nebert DW, Jefcoate CR, DiGiovanni J.

Chem Res Toxicol. 2004 Dec;17(12):1667-74.

PMID:
15606143
8.

Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential.

Tilton SC, Siddens LK, Krueger SK, Larkin AJ, Löhr CV, Williams DE, Baird WM, Waters KM.

Toxicol Sci. 2015 Jul;146(1):135-45. doi: 10.1093/toxsci/kfv080. Epub 2015 Apr 22.

9.

Arylhydrocarbon receptor-dependent induction of liver and lung cytochromes P450 1A1, 1A2, and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in genetically engineered C57BL/6J mice.

Shimada T, Inoue K, Suzuki Y, Kawai T, Azuma E, Nakajima T, Shindo M, Kurose K, Sugie A, Yamagishi Y, Fujii-Kuriyama Y, Hashimoto M.

Carcinogenesis. 2002 Jul;23(7):1199-207.

PMID:
12117779
10.

Tissue-specific induction of cytochromes P450 1A1 and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in engineered C57BL/6J mice of arylhydrocarbon receptor gene.

Shimada T, Sugie A, Shindo M, Nakajima T, Azuma E, Hashimoto M, Inoue K.

Toxicol Appl Pharmacol. 2003 Feb 15;187(1):1-10.

PMID:
12628579
12.

DNA adducts formation and induction of apoptosis in rat liver epithelial 'stem-like' cells exposed to carcinogenic polycyclic aromatic hydrocarbons.

Topinka J, Marvanová S, Vondrácek J, Sevastyanova O, Nováková Z, Krcmár P, Pencíková K, Machala M.

Mutat Res. 2008 Feb 1;638(1-2):122-32. Epub 2007 Sep 16.

PMID:
17961608
13.

Competitive inhibition of carcinogen-activating CYP1A1 and CYP1B1 enzymes by a standardized complex mixture of PAH extracted from coal tar.

Mahadevan B, Marston CP, Luch A, Dashwood WM, Brooks E, Pereira C, Doehmer J, Baird WM.

Int J Cancer. 2007 Mar 15;120(6):1161-8.

14.

Up-regulation of CYP1A/B in rat lung and liver, and human liver precision-cut slices by a series of polycyclic aromatic hydrocarbons; association with the Ah locus and importance of molecular size.

Pushparajah DS, Umachandran M, Nazir T, Plant KE, Plant N, Lewis DF, Ioannides C.

Toxicol In Vitro. 2008 Feb;22(1):128-45. Epub 2007 Sep 1.

PMID:
17920237
15.
16.

Tissue specific induction of cytochrome P450 (CYP) 1A1 and 1B1 in rat liver and lung following in vitro (tissue slice) and in vivo exposure to benzo(a)pyrene.

Harrigan JA, McGarrigle BP, Sutter TR, Olson JR.

Toxicol In Vitro. 2006 Jun;20(4):426-38. Epub 2005 Sep 28.

PMID:
16198082
17.

Aryl hydrocarbon receptor-mediated activity of mutagenic polycyclic aromatic hydrocarbons determined using in vitro reporter gene assay.

Machala M, Vondrácek J, Bláha L, Ciganek M, Neca JV.

Mutat Res. 2001 Oct 18;497(1-2):49-62.

PMID:
11525907
19.

Classification of polycyclic aromatic hydrocarbons based on mutagenicity in lung tissue through DNA microarray.

Hirano M, Tanaka S, Asami O.

Environ Toxicol. 2013 Nov;28(11):652-9. doi: 10.1002/tox.20761. Epub 2011 Sep 2.

PMID:
21887816
20.

Sex differences in susceptibility to PAHs is an intrinsic property of human lung adenocarcinoma cells.

Uppstad H, Osnes GH, Cole KJ, Phillips DH, Haugen A, Mollerup S.

Lung Cancer. 2011 Mar;71(3):264-70. doi: 10.1016/j.lungcan.2010.09.006. Epub 2010 Oct 15.

PMID:
20951464

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