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Items: 1 to 20 of 110

1.

Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol.

Liu SY, Aliyari R, Chikere K, Li G, Marsden MD, Smith JK, Pernet O, Guo H, Nusbaum R, Zack JA, Freiberg AN, Su L, Lee B, Cheng G.

Immunity. 2013 Jan 24;38(1):92-105. doi: 10.1016/j.immuni.2012.11.005. Epub 2012 Dec 27.

2.

25-Hydroxycholesterol Inhibition of Lassa Virus Infection through Aberrant GP1 Glycosylation.

Shrivastava-Ranjan P, Bergeron É, Chakrabarti AK, Albariño CG, Flint M, Nichol ST, Spiropoulou CF.

MBio. 2016 Dec 20;7(6). pii: e01808-16. doi: 10.1128/mBio.01808-16.

3.

Interferon-inducible cholesterol-25-hydroxylase inhibits hepatitis C virus replication via distinct mechanisms.

Chen Y, Wang S, Yi Z, Tian H, Aliyari R, Li Y, Chen G, Liu P, Zhong J, Chen X, Du P, Su L, Qin FX, Deng H, Cheng G.

Sci Rep. 2014 Dec 3;4:7242. doi: 10.1038/srep07242.

4.

Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation.

Anggakusuma, Romero-Brey I, Berger C, Colpitts CC, Boldanova T, Engelmann M, Todt D, Perin PM, Behrendt P, Vondran FW, Xu S, Goffinet C, Schang LM, Heim MH, Bartenschlager R, Pietschmann T, Steinmann E.

Hepatology. 2015 Sep;62(3):702-14. doi: 10.1002/hep.27913. Epub 2015 Jul 28.

PMID:
25999047
5.

Cholesterol 25-Hydroxylase Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication through Enzyme Activity-Dependent and -Independent Mechanisms.

Ke W, Fang L, Jing H, Tao R, Wang T, Li Y, Long S, Wang D, Xiao S.

J Virol. 2017 Sep 12;91(19). pii: e00827-17. doi: 10.1128/JVI.00827-17. Print 2017 Oct 1.

PMID:
28724759
6.

Identification of Cholesterol 25-Hydroxylase as a Novel Host Restriction Factor and a Part of the Primary Innate Immune Responses against Hepatitis C Virus Infection.

Xiang Y, Tang JJ, Tao W, Cao X, Song BL, Zhong J.

J Virol. 2015 Jul;89(13):6805-16. doi: 10.1128/JVI.00587-15. Epub 2015 Apr 22.

7.

Cholesterol 25-hydroxylase acts as a host restriction factor on pseudorabies virus replication.

Wang J, Zeng L, Zhang L, Guo ZZ, Lu SF, Ming SL, Li GL, Wan B, Tian KG, Yang GY, Chu BB.

J Gen Virol. 2017 Jun;98(6):1467-1476. doi: 10.1099/jgv.0.000797. Epub 2017 Jun 20.

PMID:
28631596
8.

The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response.

Blanc M, Hsieh WY, Robertson KA, Kropp KA, Forster T, Shui G, Lacaze P, Watterson S, Griffiths SJ, Spann NJ, Meljon A, Talbot S, Krishnan K, Covey DF, Wenk MR, Craigon M, Ruzsics Z, Haas J, Angulo A, Griffiths WJ, Glass CK, Wang Y, Ghazal P.

Immunity. 2013 Jan 24;38(1):106-18. doi: 10.1016/j.immuni.2012.11.004. Epub 2012 Dec 27.

9.

Armand-Frappier Outstanding Student Award--The emerging role of 25-hydroxycholesterol in innate immunity.

Singaravelu R, Srinivasan P, Pezacki JP.

Can J Microbiol. 2015 Aug;61(8):521-30. doi: 10.1139/cjm-2015-0292. Epub 2015 Jun 10. Review.

10.

25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model.

Li C, Deng YQ, Wang S, Ma F, Aliyari R, Huang XY, Zhang NN, Watanabe M, Dong HL, Liu P, Li XF, Ye Q, Tian M, Hong S, Fan J, Zhao H, Li L, Vishlaghi N, Buth JE, Au C, Liu Y, Lu N, Du P, Qin FX, Zhang B, Gong D, Dai X, Sun R, Novitch BG, Xu Z, Qin CF, Cheng G.

Immunity. 2017 Mar 21;46(3):446-456. doi: 10.1016/j.immuni.2017.02.012. Epub 2017 Mar 14.

PMID:
28314593
11.

Disruption of Rorα1 and cholesterol 25-hydroxylase expression attenuates phagocytosis in male Rorαsg/sg mice.

Tuong ZK, Lau P, Yeo JC, Pearen MA, Wall AA, Stanley AC, Stow JL, Muscat GE.

Endocrinology. 2013 Jan;154(1):140-9. doi: 10.1210/en.2012-1889. Epub 2012 Dec 13.

PMID:
23239817
12.

Herpes simplex virus type 1 abrogates the antiviral activity of Ch25h via its virion host shutoff protein.

You H, Yuan H, Fu W, Su C, Wang W, Cheng T, Zheng C.

Antiviral Res. 2017 Jul;143:69-73. doi: 10.1016/j.antiviral.2017.04.004. Epub 2017 Apr 9.

PMID:
28404225
13.

Phospholipid scramblase 1 potentiates the antiviral activity of interferon.

Dong B, Zhou Q, Zhao J, Zhou A, Harty RN, Bose S, Banerjee A, Slee R, Guenther J, Williams BR, Wiedmer T, Sims PJ, Silverman RH.

J Virol. 2004 Sep;78(17):8983-93.

14.

Inhibition of pathogenic non-enveloped viruses by 25-hydroxycholesterol and 27-hydroxycholesterol.

Civra A, Cagno V, Donalisio M, Biasi F, Leonarduzzi G, Poli G, Lembo D.

Sci Rep. 2014 Dec 15;4:7487. doi: 10.1038/srep07487.

15.

Interferon-independent antiviral activity of 25-hydroxycholesterol in a teleost fish.

Pereiro P, Forn-Cuní G, Dios S, Coll J, Figueras A, Novoa B.

Antiviral Res. 2017 Sep;145:146-159. doi: 10.1016/j.antiviral.2017.08.003. Epub 2017 Aug 5.

PMID:
28789986
16.

Systematic identification of type I and type II interferon-induced antiviral factors.

Liu SY, Sanchez DJ, Aliyari R, Lu S, Cheng G.

Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4239-44. doi: 10.1073/pnas.1114981109. Epub 2012 Feb 27.

17.

Cholesterol 25-hydroxylase is an interferon-inducible factor that protects against porcine reproductive and respiratory syndrome virus infection.

Song Z, Zhang Q, Liu X, Bai J, Zhao Y, Wang X, Jiang P.

Vet Microbiol. 2017 Oct;210:153-161. doi: 10.1016/j.vetmic.2017.09.011. Epub 2017 Sep 20.

PMID:
29103685
18.

ISG20, a new interferon-induced RNase specific for single-stranded RNA, defines an alternative antiviral pathway against RNA genomic viruses.

Espert L, Degols G, Gongora C, Blondel D, Williams BR, Silverman RH, Mechti N.

J Biol Chem. 2003 May 2;278(18):16151-8. Epub 2003 Feb 19.

19.

Oxysterols in the brain of the cholesterol 24-hydroxylase knockout mouse.

Meljon A, Wang Y, Griffiths WJ.

Biochem Biophys Res Commun. 2014 Apr 11;446(3):768-74. doi: 10.1016/j.bbrc.2014.01.153. Epub 2014 Jan 31.

20.

RORα and 25-Hydroxycholesterol Crosstalk Regulates Lipid Droplet Homeostasis in Macrophages.

Tuong ZK, Lau P, Du X, Condon ND, Goode JM, Oh TG, Yeo JC, Muscat GE, Stow JL.

PLoS One. 2016 Jan 26;11(1):e0147179. doi: 10.1371/journal.pone.0147179. eCollection 2016.

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