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Items: 1 to 20 of 102

1.

Hepatocellular carcinomas in B6C3F1 mice treated with Ginkgo biloba extract for two years differ from spontaneous liver tumors in cancer gene mutations and genomic pathways.

Hoenerhoff MJ, Pandiri AR, Snyder SA, Hong HH, Ton TV, Peddada S, Shockley K, Witt K, Chan P, Rider C, Kooistra L, Nyska A, Sills RC.

Toxicol Pathol. 2013 Aug;41(6):826-41. doi: 10.1177/0192623312467520. Epub 2012 Dec 21.

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Toxicity and carcinogenicity studies of Ginkgo biloba extract in rat and mouse: liver, thyroid, and nose are targets.

Rider CV, Nyska A, Cora MC, Kissling GE, Smith C, Travlos GS, Hejtmancik MR, Fomby LM, Colleton CA, Ryan MJ, Kooistra L, Morrison JP, Chan PC.

Toxicol Pathol. 2014 Jul;42(5):830-43. doi: 10.1177/0192623313501235. Epub 2013 Aug 19.

4.

Essential role of constitutive androstane receptor in Ginkgo biloba extract induced liver hypertrophy and hepatocarcinogenesis.

Maeda J, Inoue K, Ichimura R, Takahashi M, Kodama Y, Saito N, Yoshida M.

Food Chem Toxicol. 2015 Sep;83:201-9. doi: 10.1016/j.fct.2015.06.010. Epub 2015 Jun 24.

PMID:
26115596
5.

Gene expression and mutation assessment provide clues of genetic and epigenetic mechanisms in liver tumors of oxazepam-exposed mice.

Lahousse SA, Hoenerhoff M, Collins J, Ton TV, Masinde T, Olson D, Rebolloso Y, Koujitani T, Tomer KB, Hong HH, Bucher J, Sills RC.

Vet Pathol. 2011 Jul;48(4):875-84. doi: 10.1177/0300985810390019. Epub 2010 Dec 7.

PMID:
21147764
6.
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Ginkgo biloba extract promotes osteogenic differentiation of human bone marrow mesenchymal stem cells in a pathway involving Wnt/β-catenin signaling.

Gu Q, Chen C, Zhang Z, Wu Z, Fan X, Zhang Z, Di W, Shi L.

Pharmacol Res. 2015 Jul;97:70-8. doi: 10.1016/j.phrs.2015.04.004. Epub 2015 Apr 23.

PMID:
25917209
8.

Ginkgo biloba extract induces gene expression changes in xenobiotics metabolism and the Myc-centered network.

Guo L, Mei N, Liao W, Chan PC, Fu PP.

OMICS. 2010 Feb;14(1):75-90. doi: 10.1089/omi.2009.0115.

9.

In vivo genotoxicity of Ginkgo biloba extract in gpt delta mice and constitutive androstane receptor knockout mice.

Maeda J, Kijima A, Inoue K, Ishii Y, Ichimura R, Takasu S, Kuroda K, Matsushita K, Kodama Y, Saito N, Umemura T, Yoshida M.

Toxicol Sci. 2014 Aug 1;140(2):298-306. doi: 10.1093/toxsci/kfu090. Epub 2014 May 13.

PMID:
24824808
10.

Mechanistic evaluation of Ginkgo biloba leaf extract-induced genotoxicity in L5178Y cells.

Lin H, Guo X, Zhang S, Dial SL, Guo L, Manjanatha MG, Moore MM, Mei N.

Toxicol Sci. 2014 Jun;139(2):338-49. doi: 10.1093/toxsci/kfu037. Epub 2014 Mar 4.

PMID:
24595819
11.
12.

Global gene profiling of spontaneous hepatocellular carcinoma in B6C3F1 mice: similarities in the molecular landscape with human liver cancer.

Hoenerhoff MJ, Pandiri AR, Lahousse SA, Hong HH, Ton TV, Masinde T, Auerbach SS, Gerrish K, Bushel PR, Shockley KR, Peddada SD, Sills RC.

Toxicol Pathol. 2011 Jun;39(4):678-99. doi: 10.1177/0192623311407213. Epub 2011 May 13.

13.

Ginkgo Biloba Extract Attenuates Oxidative Stress and Apoptosis in Mouse Cochlear Neural Stem Cells.

Wang C, Wang B.

Phytother Res. 2016 May;30(5):774-80. doi: 10.1002/ptr.5572. Epub 2016 Jan 22.

PMID:
26799058
14.

ras proto-oncogene activation in dichloroacetic acid-, trichloroethylene- and tetrachloroethylene-induced liver tumors in B6C3F1 mice.

Anna CH, Maronpot RR, Pereira MA, Foley JF, Malarkey DE, Anderson MW.

Carcinogenesis. 1994 Oct;15(10):2255-61.

PMID:
7955063
15.

Low frequency of H-ras mutations in hepatocellular adenomas and carcinomas and in hepatoblastomas from B6C3F1 mice exposed to oxazepam in the diet.

Devereux TR, White CM, Sills RC, Bucher JR, Maronpot RR, Anderson MW.

Carcinogenesis. 1994 May;15(5):1083-7.

PMID:
8200073
16.

[The effect of extract of ginkgo biloba leaf during the formation of HBV-related hepatocellular carcinoma].

Wang WW, Guo JC, Xun YH, Xiao LN, Shi WZ, Shi JP, Lou GQ.

Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2011 Oct;25(5):325-7. Chinese.

PMID:
22338214
17.

2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) promotes mouse hepatocarcinogenesis by activating transforming growth factor-β and Wnt/β-catenin signaling pathways.

Xie XL, Wei M, Kakehashi A, Yamano S, Tajiri M, Wanibuchi H.

Toxicol Sci. 2012 Feb;125(2):392-400. doi: 10.1093/toxsci/kfr314. Epub 2011 Nov 17.

PMID:
22094457
18.

Biochemical and molecular evidences for the antitumor potential of Ginkgo biloba leaves extract in rodents.

Ahmed HH, Shousha WG, El-Mezayen HA, El-Toumy SA, Sayed AH, Ramadan AR.

Acta Biochim Pol. 2017;64(1):25-33. doi: 10.18388/abp.2015_1200. Epub 2016 Oct 14.

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