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Items: 1 to 20 of 123

1.

DKK2 mediates osteolysis, invasiveness, and metastatic spread in Ewing sarcoma.

Hauer K, Calzada-Wack J, Steiger K, Grunewald TG, Baumhoer D, Plehm S, Buch T, Prazeres da Costa O, Esposito I, Burdach S, Richter GH.

Cancer Res. 2013 Jan 15;73(2):967-77. doi: 10.1158/0008-5472.CAN-12-1492. Epub 2012 Nov 30.

2.

STEAP1 is associated with the invasive and oxidative stress phenotype of Ewing tumors.

Grunewald TG, Diebold I, Esposito I, Plehm S, Hauer K, Thiel U, da Silva-Buttkus P, Neff F, Unland R, Müller-Tidow C, Zobywalski C, Lohrig K, Lewandrowski U, Sickmann A, Prazeres da Costa O, Görlach A, Cossarizza A, Butt E, Richter GH, Burdach S.

Mol Cancer Res. 2012 Jan;10(1):52-65. doi: 10.1158/1541-7786.MCR-11-0524. Epub 2011 Nov 11.

3.

G-Protein coupled receptor 64 promotes invasiveness and metastasis in Ewing sarcomas through PGF and MMP1.

Richter GH, Fasan A, Hauer K, Grunewald TG, Berns C, Rössler S, Naumann I, Staege MS, Fulda S, Esposito I, Burdach S.

J Pathol. 2013 May;230(1):70-81. doi: 10.1002/path.4170. Epub 2013 Mar 14.

PMID:
23338946
4.

Stress-induced CXCR4 promotes migration and invasion of ewing sarcoma.

Krook MA, Nicholls LA, Scannell CA, Chugh R, Thomas DG, Lawlor ER.

Mol Cancer Res. 2014 Jun;12(6):953-64. doi: 10.1158/1541-7786.MCR-13-0668. Epub 2014 Mar 20.

5.

Epigenetic silencing of DKK2 and Wnt signal pathway components in human ovarian carcinoma.

Zhu J, Zhang S, Gu L, Di W.

Carcinogenesis. 2012 Dec;33(12):2334-43. doi: 10.1093/carcin/bgs278. Epub 2012 Sep 10.

PMID:
22964660
6.

Pathogenic role of connective tissue growth factor (CTGF/CCN2) in osteolytic metastasis of breast cancer.

Shimo T, Kubota S, Yoshioka N, Ibaragi S, Isowa S, Eguchi T, Sasaki A, Takigawa M.

J Bone Miner Res. 2006 Jul;21(7):1045-59.

7.

Reactivation of TWIST1 contributes to Ewing sarcoma metastasis.

Choo S, Wang P, Newbury R, Roberts W, Yang J.

Pediatr Blood Cancer. 2018 Jan;65(1). doi: 10.1002/pbc.26721. Epub 2017 Sep 5.

PMID:
28873262
8.

WT1 regulates angiogenesis in Ewing Sarcoma.

Katuri V, Gerber S, Qiu X, McCarty G, Goldstein SD, Hammers H, Montgomery E, Chen AR, Loeb DM.

Oncotarget. 2014 May 15;5(9):2436-49.

9.

Development of a preclinical orthotopic xenograft model of ewing sarcoma and other human malignant bone disease using advanced in vivo imaging.

Vormoor B, Knizia HK, Batey MA, Almeida GS, Wilson I, Dildey P, Sharma A, Blair H, Hide IG, Heidenreich O, Vormoor J, Maxwell RJ, Bacon CM.

PLoS One. 2014 Jan 7;9(1):e85128. doi: 10.1371/journal.pone.0085128. eCollection 2014.

10.

Cathepsin G enhances mammary tumor-induced osteolysis by generating soluble receptor activator of nuclear factor-kappaB ligand.

Wilson TJ, Nannuru KC, Futakuchi M, Sadanandam A, Singh RK.

Cancer Res. 2008 Jul 15;68(14):5803-11. doi: 10.1158/0008-5472.CAN-07-5889.

11.

Stable interference of EWS-FLI1 in an Ewing sarcoma cell line impairs IGF-1/IGF-1R signalling and reveals TOPK as a new target.

Herrero-Martín D, Osuna D, Ordóñez JL, Sevillano V, Martins AS, Mackintosh C, Campos M, Madoz-Gúrpide J, Otero-Motta AP, Caballero G, Amaral AT, Wai DH, Braun Y, Eisenacher M, Schaefer KL, Poremba C, de Alava E.

Br J Cancer. 2009 Jul 7;101(1):80-90. doi: 10.1038/sj.bjc.6605104. Epub 2009 Jun 2.

12.

Runx2 induces bone osteolysis by transcriptional suppression of TSSC1.

Wang DC, Wang HF, Yuan ZN.

Biochem Biophys Res Commun. 2013 Sep 6;438(4):635-9. doi: 10.1016/j.bbrc.2013.07.131. Epub 2013 Aug 8.

PMID:
23933319
13.

EWS/ETS regulates the expression of the Dickkopf family in Ewing family tumor cells.

Miyagawa Y, Okita H, Itagaki M, Toyoda M, Katagiri YU, Fujimoto J, Hata J, Umezawa A, Kiyokawa N.

PLoS One. 2009;4(2):e4634. doi: 10.1371/journal.pone.0004634. Epub 2009 Feb 27.

14.

Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis.

Guise TA, Yin JJ, Taylor SD, Kumagai Y, Dallas M, Boyce BF, Yoneda T, Mundy GR.

J Clin Invest. 1996 Oct 1;98(7):1544-9.

15.

Oncostatin M is a growth factor for Ewing sarcoma.

David E, Tirode F, Baud'huin M, Guihard P, Laud K, Delattre O, Heymann MF, Heymann D, Redini F, Blanchard F.

Am J Pathol. 2012 Nov;181(5):1782-95. doi: 10.1016/j.ajpath.2012.07.023. Epub 2012 Sep 13.

PMID:
22982441
16.

Differentially expressed miRNAs in Ewing sarcoma compared to mesenchymal stem cells: low miR-31 expression with effects on proliferation and invasion.

Karnuth B, Dedy N, Spieker T, Lawlor ER, Gattenlöhner S, Ranft A, Dirksen U, Jürgens H, Bräuninger A.

PLoS One. 2014 Mar 25;9(3):e93067. doi: 10.1371/journal.pone.0093067. eCollection 2014.

17.

Identification of the functional role of peroxiredoxin 6 in the progression of breast cancer.

Chang XZ, Li DQ, Hou YF, Wu J, Lu JS, Di GH, Jin W, Ou ZL, Shen ZZ, Shao ZM.

Breast Cancer Res. 2007;9(6):R76.

18.

PAUF functions in the metastasis of human pancreatic cancer cells and upregulates CXCR4 expression.

Lee Y, Kim SJ, Park HD, Park EH, Huang SM, Jeon SB, Kim JM, Lim DS, Koh SS.

Oncogene. 2010 Jan 7;29(1):56-67. doi: 10.1038/onc.2009.298. Epub 2009 Sep 28.

PMID:
19784070
19.

Plumbagin inhibits breast tumor bone metastasis and osteolysis by modulating the tumor-bone microenvironment.

Li Z, Xiao J, Wu X, Li W, Yang Z, Xie J, Xu L, Cai X, Lin Z, Guo W, Luo J, Liu M.

Curr Mol Med. 2012 Sep;12(8):967-81.

PMID:
22574935
20.

Lack of matrix metalloproteinase (MMP)-1 and -3 expression in Ewing sarcoma may be due to loss of accessibility of the MMP regulatory element to the specific fusion protein in vivo.

Yabe H, Fukuma M, Urano F, Yoshida K, Kato S, Toyama Y, Hata J, Umezawa A.

Biochem Biophys Res Commun. 2002 Apr 26;293(1):61-71.

PMID:
12054564

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