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Items: 1 to 20 of 59

1.

PAR1 contributes to influenza A virus pathogenicity in mice.

Khoufache K, Berri F, Nacken W, Vogel AB, Delenne M, Camerer E, Coughlin SR, Carmeliet P, Lina B, Rimmelzwaan GF, Planz O, Ludwig S, Riteau B.

J Clin Invest. 2013 Jan;123(1):206-14. doi: 10.1172/JCI61667. Epub 2012 Dec 3.

2.

Viral replication rate regulates clinical outcome and CD8 T cell responses during highly pathogenic H5N1 influenza virus infection in mice.

Hatta Y, Hershberger K, Shinya K, Proll SC, Dubielzig RR, Hatta M, Katze MG, Kawaoka Y, Suresh M.

PLoS Pathog. 2010 Oct 7;6(10):e1001139. doi: 10.1371/journal.ppat.1001139.

3.

Low-dose interferon Type I treatment is effective against H5N1 and swine-origin H1N1 influenza A viruses in vitro and in vivo.

Haasbach E, Droebner K, Vogel AB, Planz O.

J Interferon Cytokine Res. 2011 Jun;31(6):515-25. doi: 10.1089/jir.2010.0071. Epub 2011 Feb 16.

PMID:
21323570
4.

Plasminogen controls inflammation and pathogenesis of influenza virus infections via fibrinolysis.

Berri F, Rimmelzwaan GF, Hanss M, Albina E, Foucault-Grunenwald ML, LĂȘ VB, Vogelzang-van Trierum SE, Gil P, Camerer E, Martinez D, Lina B, Lijnen R, Carmeliet P, Riteau B.

PLoS Pathog. 2013 Mar;9(3):e1003229. doi: 10.1371/journal.ppat.1003229. Epub 2013 Mar 21.

5.

Simvastatin and oseltamivir combination therapy does not improve the effectiveness of oseltamivir alone following highly pathogenic avian H5N1 influenza virus infection in mice.

Belser JA, Szretter KJ, Katz JM, Tumpey TM.

Virology. 2013 Apr 25;439(1):42-6. doi: 10.1016/j.virol.2013.01.017. Epub 2013 Mar 1.

6.

Lethal dissemination of H5N1 influenza virus is associated with dysregulation of inflammation and lipoxin signaling in a mouse model of infection.

Cilloniz C, Pantin-Jackwood MJ, Ni C, Goodman AG, Peng X, Proll SC, Carter VS, Rosenzweig ER, Szretter KJ, Katz JM, Korth MJ, Swayne DE, Tumpey TM, Katze MG.

J Virol. 2010 Aug;84(15):7613-24. doi: 10.1128/JVI.00553-10. Epub 2010 May 26.

7.

Inducible nitric oxide contributes to viral pathogenesis following highly pathogenic influenza virus infection in mice.

Perrone LA, Belser JA, Wadford DA, Katz JM, Tumpey TM.

J Infect Dis. 2013 May 15;207(10):1576-84. doi: 10.1093/infdis/jit062. Epub 2013 Feb 18.

PMID:
23420903
8.

Within-Host Models of High and Low Pathogenic Influenza Virus Infections: The Role of Macrophages.

Pawelek KA, Dor D Jr, Salmeron C, Handel A.

PLoS One. 2016 Feb 26;11(2):e0150568. doi: 10.1371/journal.pone.0150568. eCollection 2016.

9.

The host protease TMPRSS2 plays a major role in in vivo replication of emerging H7N9 and seasonal influenza viruses.

Sakai K, Ami Y, Tahara M, Kubota T, Anraku M, Abe M, Nakajima N, Sekizuka T, Shirato K, Suzaki Y, Ainai A, Nakatsu Y, Kanou K, Nakamura K, Suzuki T, Komase K, Nobusawa E, Maenaka K, Kuroda M, Hasegawa H, Kawaoka Y, Tashiro M, Takeda M.

J Virol. 2014 May;88(10):5608-16. doi: 10.1128/JVI.03677-13. Epub 2014 Mar 5.

10.

Pathogenesis of pandemic influenza A (H1N1) and triple-reassortant swine influenza A (H1) viruses in mice.

Belser JA, Wadford DA, Pappas C, Gustin KM, Maines TR, Pearce MB, Zeng H, Swayne DE, Pantin-Jackwood M, Katz JM, Tumpey TM.

J Virol. 2010 May;84(9):4194-203. doi: 10.1128/JVI.02742-09. Epub 2010 Feb 24.

11.

Caspase-1 deficient mice are more susceptible to influenza A virus infection with PA variation.

Huang CH, Chen CJ, Yen CT, Yu CP, Huang PN, Kuo RL, Lin SJ, Chang CK, Shih SR.

J Infect Dis. 2013 Dec 1;208(11):1898-905. doi: 10.1093/infdis/jit381. Epub 2013 Jul 30.

PMID:
23901080
12.

Protective role for protease-activated receptor-2 against influenza virus pathogenesis via an IFN-gamma-dependent pathway.

Khoufache K, LeBouder F, Morello E, Laurent F, Riffault S, Andrade-Gordon P, Boullier S, Rousset P, Vergnolle N, Riteau B.

J Immunol. 2009 Jun 15;182(12):7795-802. doi: 10.4049/jimmunol.0803743.

13.

2009 pandemic H1N1 influenza A virus strains display differential pathogenicity in C57BL/6J but not BALB/c mice.

Otte A, Gabriel G.

Virulence. 2011 Nov-Dec;2(6):563-6. doi: 10.4161/viru.2.6.18148. Epub 2011 Nov 1.

PMID:
22030859
14.

Highly pathogenic avian influenza viruses inhibit effective immune responses of human blood-derived macrophages.

Friesenhagen J, Boergeling Y, Hrincius E, Ludwig S, Roth J, Viemann D.

J Leukoc Biol. 2012 Jul;92(1):11-20. doi: 10.1189/jlb.0911479. Epub 2012 Mar 21.

15.

Editorial: macrophage heterogeneity and responses to influenza virus infection.

Lee SM, Dutry I, Peiris JS.

J Leukoc Biol. 2012 Jul;92(1):1-4. doi: 10.1189/jlb.0312130. No abstract available.

16.

The aminobisphosphonate pamidronate controls influenza pathogenesis by expanding a gammadelta T cell population in humanized mice.

Tu W, Zheng J, Liu Y, Sia SF, Liu M, Qin G, Ng IH, Xiang Z, Lam KT, Peiris JS, Lau YL.

J Exp Med. 2011 Jul 4;208(7):1511-22. doi: 10.1084/jem.20110226. Epub 2011 Jun 27.

17.

Protection against H5N1 highly pathogenic avian and pandemic (H1N1) 2009 influenza virus infection in cynomolgus monkeys by an inactivated H5N1 whole particle vaccine.

Nakayama M, Shichinohe S, Itoh Y, Ishigaki H, Kitano M, Arikata M, Pham VL, Ishida H, Kitagawa N, Okamatsu M, Sakoda Y, Ichikawa T, Tsuchiya H, Nakamura S, Le QM, Ito M, Kawaoka Y, Kida H, Ogasawara K.

PLoS One. 2013 Dec 23;8(12):e82740. doi: 10.1371/journal.pone.0082740. eCollection 2013.

18.

Efficacy of the new neuraminidase inhibitor CS-8958 against H5N1 influenza viruses.

Kiso M, Kubo S, Ozawa M, Le QM, Nidom CA, Yamashita M, Kawaoka Y.

PLoS Pathog. 2010 Feb 26;6(2):e1000786. doi: 10.1371/journal.ppat.1000786.

19.

Dissecting influenza virus pathogenesis uncovers a novel chemical approach to combat the infection.

Oldstone MB, Teijaro JR, Walsh KB, Rosen H.

Virology. 2013 Jan 5;435(1):92-101. doi: 10.1016/j.virol.2012.09.039. Review.

20.

Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets.

Imai M, Watanabe T, Hatta M, Das SC, Ozawa M, Shinya K, Zhong G, Hanson A, Katsura H, Watanabe S, Li C, Kawakami E, Yamada S, Kiso M, Suzuki Y, Maher EA, Neumann G, Kawaoka Y.

Nature. 2012 May 2;486(7403):420-8. doi: 10.1038/nature10831.

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