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Oxidative stress is linked to ERK1/2-p16 signaling-mediated growth defect in ATM-deficient astrocytes.

Kim J, Wong PK.

J Biol Chem. 2009 May 22;284(21):14396-404. doi: 10.1074/jbc.M808116200. Epub 2009 Mar 25.


Activation of AMP-activated protein kinase in cerebella of Atm-/- mice is attributable to accumulation of reactive oxygen species.

Kuang X, Yan M, Ajmo JM, Scofield VL, Stoica G, Wong PK.

Biochem Biophys Res Commun. 2012 Feb 10;418(2):267-72. doi: 10.1016/j.bbrc.2012.01.008. Epub 2012 Jan 10.


ATM-dependent activation of the gene encoding MAP kinase phosphatase 5 by radiomimetic DNA damage.

Bar-Shira A, Rashi-Elkeles S, Zlochover L, Moyal L, Smorodinsky NI, Seger R, Shiloh Y.

Oncogene. 2002 Jan 24;21(5):849-55.


Oxidative stress is responsible for deficient survival and dendritogenesis in purkinje neurons from ataxia-telangiectasia mutated mutant mice.

Chen P, Peng C, Luff J, Spring K, Watters D, Bottle S, Furuya S, Lavin MF.

J Neurosci. 2003 Dec 10;23(36):11453-60.


Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway.

Kovarik P, Stoiber D, Eyers PA, Menghini R, Neininger A, Gaestel M, Cohen P, Decker T.

Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13956-61.


ATM: the protein encoded by the gene mutated in the radiosensitive syndrome ataxia-telangiectasia.

Lavin MF, Khanna KK.

Int J Radiat Biol. 1999 Oct;75(10):1201-14. Review.


TEGDMA-induced oxidative DNA damage and activation of ATM and MAP kinases.

Eckhardt A, Gerstmayr N, Hiller KA, Bolay C, Waha C, Spagnuolo G, Camargo C, Schmalz G, Schweikl H.

Biomaterials. 2009 Apr;30(11):2006-14. doi: 10.1016/j.biomaterials.2008.12.045. Epub 2009 Jan 12.


Alteration in 5-hydroxymethylcytosine-mediated epigenetic regulation leads to Purkinje cell vulnerability in ATM deficiency.

Jiang D, Zhang Y, Hart RP, Chen J, Herrup K, Li J.

Brain. 2015 Dec;138(Pt 12):3520-36. doi: 10.1093/brain/awv284. Epub 2015 Oct 27.


Diverse mechanisms of myocardial p38 mitogen-activated protein kinase activation: evidence for MKK-independent activation by a TAB1-associated mechanism contributing to injury during myocardial ischemia.

Tanno M, Bassi R, Gorog DA, Saurin AT, Jiang J, Heads RJ, Martin JL, Davis RJ, Flavell RA, Marber MS.

Circ Res. 2003 Aug 8;93(3):254-61. Epub 2003 Jun 26.


Residual ataxia telangiectasia mutated protein function in cells from ataxia telangiectasia patients, with 5762ins137 and 7271T-->G mutations, showing a less severe phenotype.

Stewart GS, Last JI, Stankovic T, Haites N, Kidd AM, Byrd PJ, Taylor AM.

J Biol Chem. 2001 Aug 10;276(32):30133-41. Epub 2001 May 29.


Inhibition of p38 mitogen-activated protein kinase impairs influenza virus-induced primary and secondary host gene responses and protects mice from lethal H5N1 infection.

Börgeling Y, Schmolke M, Viemann D, Nordhoff C, Roth J, Ludwig S.

J Biol Chem. 2014 Jan 3;289(1):13-27. doi: 10.1074/jbc.M113.469239. Epub 2013 Nov 4.


Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice.

Borghesani PR, Alt FW, Bottaro A, Davidson L, Aksoy S, Rathbun GA, Roberts TM, Swat W, Segal RA, Gu Y.

Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3336-41.

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