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Items: 1 to 20 of 107

1.

Phosphorylation of eukaryotic elongation factor 2 (eEF2) by cyclin A-cyclin-dependent kinase 2 regulates its inhibition by eEF2 kinase.

Hizli AA, Chi Y, Swanger J, Carter JH, Liao Y, Welcker M, Ryazanov AG, Clurman BE.

Mol Cell Biol. 2013 Feb;33(3):596-604. doi: 10.1128/MCB.01270-12. Epub 2012 Nov 26.

2.

cdc2-cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner.

Smith EM, Proud CG.

EMBO J. 2008 Apr 9;27(7):1005-16. doi: 10.1038/emboj.2008.39. Epub 2008 Mar 13.

3.

Lopinavir impairs protein synthesis and induces eEF2 phosphorylation via the activation of AMP-activated protein kinase.

Hong-Brown LQ, Brown CR, Huber DS, Lang CH.

J Cell Biochem. 2008 Oct 15;105(3):814-23. doi: 10.1002/jcb.21882.

4.

1-Benzyl-3-cetyl-2-methylimidazolium iodide (NH125) induces phosphorylation of eukaryotic elongation factor-2 (eEF2): a cautionary note on the anticancer mechanism of an eEF2 kinase inhibitor.

Chen Z, Gopalakrishnan SM, Bui MH, Soni NB, Warrior U, Johnson EF, Donnelly JB, Glaser KB.

J Biol Chem. 2011 Dec 23;286(51):43951-8. doi: 10.1074/jbc.M111.301291. Epub 2011 Oct 21.

5.

[Eukaryotic elongation factor 2 kinase and cancer].

Wang GZ, Qi X, Li J.

Yao Xue Xue Bao. 2015 Jul;50(7):808-13. Chinese.

PMID:
26552140
6.

A Ca(2+)-calmodulin-eEF2K-eEF2 signalling cascade, but not AMPK, contributes to the suppression of skeletal muscle protein synthesis during contractions.

Rose AJ, Alsted TJ, Jensen TE, Kobberø JB, Maarbjerg SJ, Jensen J, Richter EA.

J Physiol. 2009 Apr 1;587(Pt 7):1547-63. doi: 10.1113/jphysiol.2008.167528. Epub 2009 Feb 2.

7.

Thermal injury activates the eEF2K-dependent eEF2 pathway in pediatric patients.

Song J, Finnerty CC, Herndon DN, Kraft R, Boehning D, Brooks NC, Tompkins RG, Jeschke MG.

JPEN J Parenter Enteral Nutr. 2012 Sep;36(5):596-602. doi: 10.1177/0148607111422234. Epub 2012 Jan 23.

8.

Coupled activation and degradation of eEF2K regulates protein synthesis in response to genotoxic stress.

Kruiswijk F, Yuniati L, Magliozzi R, Low TY, Lim R, Bolder R, Mohammed S, Proud CG, Heck AJ, Pagano M, Guardavaccaro D.

Sci Signal. 2012 Jun 5;5(227):ra40. doi: 10.1126/scisignal.2002718.

9.

Elongation Factor 2 Kinase Is Regulated by Proline Hydroxylation and Protects Cells during Hypoxia.

Moore CE, Mikolajek H, Regufe da Mota S, Wang X, Kenney JW, Werner JM, Proud CG.

Mol Cell Biol. 2015 May;35(10):1788-804. doi: 10.1128/MCB.01457-14. Epub 2015 Mar 9.

10.

Eukaryotic elongation factor 2 kinase activity is controlled by multiple inputs from oncogenic signaling.

Wang X, Regufe da Mota S, Liu R, Moore CE, Xie J, Lanucara F, Agarwala U, Pyr Dit Ruys S, Vertommen D, Rider MH, Eyers CE, Proud CG.

Mol Cell Biol. 2014 Nov 15;34(22):4088-103. doi: 10.1128/MCB.01035-14. Epub 2014 Sep 2.

11.

Eukaryotic elongation factor 2 kinase confers tolerance to stress conditions in cancer cells.

Zhu H, Yang X, Liu J, Zhou L, Zhang C, Xu L, Qin Q, Zhan L, Lu J, Cheng H, Sun X.

Cell Stress Chaperones. 2015 Mar;20(2):217-20. doi: 10.1007/s12192-014-0545-0. Epub 2014 Sep 24. Review.

12.

Eukaryotic elongation factor-2 (eEF2): its regulation and peptide chain elongation.

Kaul G, Pattan G, Rafeequi T.

Cell Biochem Funct. 2011 Apr;29(3):227-34. doi: 10.1002/cbf.1740. Epub 2011 Mar 10. Review.

PMID:
21394738
13.

Cyclic AMP inhibits translation of cyclin D3 in T lymphocytes at the level of elongation by inducing eEF2-phosphorylation.

Gutzkow KB, Låhne HU, Naderi S, Torgersen KM, Skålhegg B, Koketsu M, Uehara Y, Blomhoff HK.

Cell Signal. 2003 Sep;15(9):871-81.

PMID:
12834812
14.
15.

Myocardial ischemia and increased heart work modulate the phosphorylation state of eukaryotic elongation factor-2.

Horman S, Beauloye C, Vertommen D, Vanoverschelde JL, Hue L, Rider MH.

J Biol Chem. 2003 Oct 24;278(43):41970-6. Epub 2003 Aug 14.

16.

Compartment-specific, differential regulation of eukaryotic elongation factor 2 and its kinase within Aplysia sensory neurons.

Weatherill DB, McCamphill PK, Pethoukov E, Dunn TW, Fan X, Sossin WS.

J Neurochem. 2011 Jun;117(5):841-55. doi: 10.1111/j.1471-4159.2011.07251.x. Epub 2011 Apr 7.

17.

The channel-kinase TRPM7 regulates phosphorylation of the translational factor eEF2 via eEF2-k.

Perraud AL, Zhao X, Ryazanov AG, Schmitz C.

Cell Signal. 2011 Mar;23(3):586-93. doi: 10.1016/j.cellsig.2010.11.011. Epub 2010 Nov 25.

18.

Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase.

Pyr Dit Ruys S, Wang X, Smith EM, Herinckx G, Hussain N, Rider MH, Vertommen D, Proud CG.

Biochem J. 2012 Mar 15;442(3):681-92. doi: 10.1042/BJ20111530. Erratum in: Biochem J. 2012 Apr 1;443(1):328.

19.
20.

Direct and indirect activation of eukaryotic elongation factor 2 kinase by AMP-activated protein kinase.

Johanns M, Pyr Dit Ruys S, Houddane A, Vertommen D, Herinckx G, Hue L, Proud CG, Rider MH.

Cell Signal. 2017 May 11;36:212-221. doi: 10.1016/j.cellsig.2017.05.010. [Epub ahead of print]

PMID:
28502587

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