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Items: 1 to 20 of 87

1.

A polymorphic microsatellite repeat within the ECE-1c promoter is involved in transcriptional start site determination, human evolution, and Alzheimer's disease.

Li Y, Seidel K, Marschall P, Klein M, Hope A, Schacherl J, Schmitz J, Menk M, Schefe JH, Reinemund J, Hugel R, Walden P, Schlosser A, Volkmer R, Schimkus J, Kölsch H, Maier W, Kornhuber J, Frölich L, Klare S, Kirsch S, Schmerbach K, Scheele S, Grittner U, Zollmann F, Goldin-Lang P, Peters O, Kintscher U, Unger T, Funke-Kaiser H.

J Neurosci. 2012 Nov 21;32(47):16807-20. doi: 10.1523/JNEUROSCI.2636-12.2012.

2.

Regulation of the major isoform of human endothelin-converting enzyme-1 by a strong housekeeping promoter modulated by polymorphic microsatellites.

Funke-Kaiser H, Thomas A, Bremer J, Kovacevic SD, Scheuch K, Bolbrinker J, Theis S, Lemmer J, Zimmermann A, Zollmann FS, Herrmann SM, Paul M, Orzechowski HD.

J Hypertens. 2003 Nov;21(11):2111-24.

PMID:
14597855
3.

Expression and functional profiling of neprilysin, insulin-degrading enzyme, and endothelin-converting enzyme in prospectively studied elderly and Alzheimer's brain.

Wang S, Wang R, Chen L, Bennett DA, Dickson DW, Wang DS.

J Neurochem. 2010 Oct;115(1):47-57. doi: 10.1111/j.1471-4159.2010.06899.x. Epub 2010 Jul 30.

4.

Characterization of the c-specific promoter of the gene encoding human endothelin-converting enzyme-1 (ECE-1).

Funke-Kaiser H, Bolbrinker J, Theis S, Lemmer J, Richter CM, Paul M, Orzechowski HD.

FEBS Lett. 2000 Jan 28;466(2-3):310-6.

5.

Evidence of alternative promoters directing isoform-specific expression of human endothelin-converting enzyme-1 mRNA in cultured endothelial cells.

Orzechowski HD, Richter CM, Funke-Kaiser H, Kröger B, Schmidt M, Menzel S, Bohnemeier H, Paul M.

J Mol Med (Berl). 1997 Jul;75(7):512-21.

PMID:
9253714
6.

Endothelin-converting enzyme-1 is expressed in human cerebral cortex and protects against Alzheimer's disease.

Funalot B, Ouimet T, Claperon A, Fallet C, Delacourte A, Epelbaum J, Subkowski T, Léonard N, Codron V, David JP, Amouyel P, Schwartz JC, Helbecque N.

Mol Psychiatry. 2004 Dec;9(12):1122-8, 1059.

PMID:
15340356
7.

Human endothelin-converting enzyme-1 beta mRNA expression is regulated by an alternative promoter.

Funke-Kaiser H, Orzechowski HD, Richter M, Paul M.

J Cardiovasc Pharmacol. 1998;31 Suppl 1:S7-9.

PMID:
9595385
8.

The role of ECE1 variants in cognitive ability in old age and Alzheimer's disease risk.

Hamilton G, Harris SE, Davies G, Liewald DC, Tenesa A, Payton A, Horan MA, Ollier WE, Pendleton N; Genetic and Environmental Risk for Alzheimer's Disease (GERAD1) Consortium, Starr JM, Porteous D, Deary IJ.

Am J Med Genet B Neuropsychiatr Genet. 2012 Sep;159B(6):696-709. doi: 10.1002/ajmg.b.32073. Epub 2012 Jun 12.

PMID:
22693153
9.

Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme.

Eckman EA, Watson M, Marlow L, Sambamurti K, Eckman CB.

J Biol Chem. 2003 Jan 24;278(4):2081-4. Epub 2002 Dec 2.

10.

Transcriptional mechanism of protein kinase C-induced isoform-specific expression of the gene for endothelin-converting enzyme-1 in human endothelial cells.

Orzechowski HD, Günther A, Menzel S, Zimmermann A, Funke-Kaiser H, Real R, Subkowski T, Zollmann FS, Paul M.

Mol Pharmacol. 2001 Dec;60(6):1332-42.

11.

Promoter polymorphisms which modulate BACE1 expression are associated with sporadic Alzheimer's disease.

Wang S, Jia J.

Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 5;153B(1):159-66. doi: 10.1002/ajmg.b.30968.

PMID:
19441127
12.

Endothelin-converting enzyme-1 promoter polymorphisms and susceptibility to sporadic late-onset Alzheimer's disease in a Chinese population.

Jin Z, Luxiang C, Huadong Z, Yanjiang W, Zhiqiang X, Hongyuan C, Lihua H, Xu Y.

Dis Markers. 2009;27(5):211-5. doi: 10.3233/DMA-2009-0665.

13.

Regulation of vascular contractility and blood pressure by the E2F2 transcription factor.

Zhou J, Zhu Y, Cheng M, Dinesh D, Thorne T, Poh KK, Liu D, Botros C, Tang YL, Reisdorph N, Kishore R, Losordo DW, Qin G.

Circulation. 2009 Sep 29;120(13):1213-21. doi: 10.1161/CIRCULATIONAHA.109.859207. Epub 2009 Sep 14.

14.

Endothelin-converting enzyme-1 (ECE-1) is a downstream target of the homeobox transcription factor Nkx2-5.

Funke-Kaiser H, Lemmer J, Langsdorff CV, Thomas A, Kovacevic SD, Strasdat M, Behrouzi T, Zollmann FS, Paul M, Orzechowski HD.

FASEB J. 2003 Aug;17(11):1487-9. Epub 2003 Jun 17.

PMID:
12824294
15.

Endothelin-converting enzyme-1 in Alzheimer's disease and vascular dementia.

Palmer JC, Kehoe PG, Love S.

Neuropathol Appl Neurobiol. 2010 Oct;36(6):487-97. doi: 10.1111/j.1365-2990.2010.01084.x. Epub 2010 Mar 22.

PMID:
20345647
16.

Hydrogen peroxide regulation of bovine endothelin-converting enzyme-1.

López-Ongil S, Saura M, Zaragoza C, Gónzalez-Santiago L, Rodríguez-Puyol M, Lowenstein CJ, Rodríguez-Puyol D.

Free Radic Biol Med. 2002 Mar 1;32(5):406-13.

PMID:
11864780
17.

Polymorphisms in human endothelin-converting enzyme (ECE-1) promoter can modulate ECE-1 gene expression.

Gentile MT, Lembo G.

J Hypertens. 2003 Nov;21(11):2013-4. No abstract available.

PMID:
14597841
18.

Human endothelin-converting enzyme (ECE-1): three isoforms with distinct subcellular localizations.

Schweizer A, Valdenaire O, Nelböck P, Deuschle U, Dumas Milne Edwards JB, Stumpf JG, Löffler BM.

Biochem J. 1997 Dec 15;328 ( Pt 3):871-7.

20.

Cloning and functional characterization of the bovine endothelin-converting enzyme-1a promoter.

Orzechowski HD, Richter CM, Funke-Kaiser H, Lemmer J, Theis S, Paul M.

Biochim Biophys Acta. 1999 Sep 3;1446(3):352-8.

PMID:
10524209

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