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Drosophila RecQ4 is directly involved in both DNA replication and the response to UV damage in S2 cells.

Crevel G, Vo N, Crevel I, Hamid S, Hoa L, Miyata S, Cotterill S.

PLoS One. 2012;7(11):e49505. doi: 10.1371/journal.pone.0049505. Epub 2012 Nov 16.


Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells.

Kliszczak M, Sedlackova H, Pitchai GP, Streicher WW, Krejci L, Hickson ID.

Oncotarget. 2015 Dec 1;6(38):40464-79. doi: 10.18632/oncotarget.6342.


Human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiation.

Thangavel S, Mendoza-Maldonado R, Tissino E, Sidorova JM, Yin J, Wang W, Monnat RJ Jr, Falaschi A, Vindigni A.

Mol Cell Biol. 2010 Mar;30(6):1382-96. doi: 10.1128/MCB.01290-09. Epub 2010 Jan 11.


Dual DNA unwinding activities of the Rothmund-Thomson syndrome protein, RECQ4.

Xu X, Liu Y.

EMBO J. 2009 Mar 4;28(5):568-77. doi: 10.1038/emboj.2009.13. Epub 2009 Jan 29.


RECQ1 plays a distinct role in cellular response to oxidative DNA damage.

Sharma S, Phatak P, Stortchevoi A, Jasin M, Larocque JR.

DNA Repair (Amst). 2012 Jun 1;11(6):537-49. doi: 10.1016/j.dnarep.2012.04.003. Epub 2012 Apr 26.


Gap-filling and bypass at the replication fork are both active mechanisms for tolerance of low-dose ultraviolet-induced DNA damage in the human genome.

Quinet A, Vessoni AT, Rocha CR, Gottifredi V, Biard D, Sarasin A, Menck CF, Stary A.

DNA Repair (Amst). 2014 Feb;14:27-38. doi: 10.1016/j.dnarep.2013.12.005. Epub 2013 Dec 28.


The helicase domain and C-terminus of human RecQL4 facilitate replication elongation on DNA templates damaged by ionizing radiation.

Kohzaki M, Chiourea M, Versini G, Adachi N, Takeda S, Gagos S, Halazonetis TD.

Carcinogenesis. 2012 Jun;33(6):1203-10. doi: 10.1093/carcin/bgs149. Epub 2012 Apr 16.


RecQ4: the second replicative helicase?

Capp C, Wu J, Hsieh TS.

Crit Rev Biochem Mol Biol. 2010 Jun;45(3):233-42. doi: 10.3109/10409231003786086. Review.


Drosophila RecQ4 has a 3'-5' DNA helicase activity that is essential for viability.

Capp C, Wu J, Hsieh TS.

J Biol Chem. 2009 Nov 6;284(45):30845-52. doi: 10.1074/jbc.M109.008052. Epub 2009 Sep 15.


Drosophila homologue of the Rothmund-Thomson syndrome gene: essential function in DNA replication during development.

Wu J, Capp C, Feng L, Hsieh TS.

Dev Biol. 2008 Nov 1;323(1):130-42. doi: 10.1016/j.ydbio.2008.08.006. Epub 2008 Aug 15.


MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication.

Xu X, Rochette PJ, Feyissa EA, Su TV, Liu Y.

EMBO J. 2009 Oct 7;28(19):3005-14. doi: 10.1038/emboj.2009.235. Epub 2009 Aug 20.


Structural and biochemical characterization of an RNA/DNA binding motif in the N-terminal domain of RecQ4 helicases.

Marino F, Mojumdar A, Zucchelli C, Bhardwaj A, Buratti E, Vindigni A, Musco G, Onesti S.

Sci Rep. 2016 Feb 18;6:21501. doi: 10.1038/srep21501.


A positive involvement of RecQL4 in UV-induced S-phase arrest.

Park SJ, Lee YJ, Beck BD, Lee SH.

DNA Cell Biol. 2006 Dec;25(12):696-703.


Requirement for functional DNA polymerase eta in genome-wide repair of UV-induced DNA damage during S phase.

Auclair Y, Rouget R, Belisle JM, Costantino S, Drobetsky EA.

DNA Repair (Amst). 2010 Jul 1;9(7):754-64. doi: 10.1016/j.dnarep.2010.03.013. Epub 2010 Apr 24.


RECQ4 selectively recognizes Holliday junctions.

Sedlackova H, Cechova B, Mlcouskova J, Krejci L.

DNA Repair (Amst). 2015 Jun;30:80-9. doi: 10.1016/j.dnarep.2015.02.020. Epub 2015 Feb 28.


Disruption of SUMO-targeted ubiquitin ligases Slx5-Slx8/RNF4 alters RecQ-like helicase Sgs1/BLM localization in yeast and human cells.

Böhm S, Mihalevic MJ, Casal MA, Bernstein KA.

DNA Repair (Amst). 2015 Feb;26:1-14. doi: 10.1016/j.dnarep.2014.12.004. Epub 2014 Dec 26.


dRecQ4 is required for DNA synthesis and essential for cell proliferation in Drosophila.

Xu Y, Lei Z, Huang H, Dui W, Liang X, Ma J, Jiao R.

PLoS One. 2009 Jul 2;4(7):e6107. doi: 10.1371/journal.pone.0006107.


FANCJ localization by mismatch repair is vital to maintain genomic integrity after UV irradiation.

Guillemette S, Branagan A, Peng M, Dhruva A, Schärer OD, Cantor SB.

Cancer Res. 2014 Feb 1;74(3):932-44. doi: 10.1158/0008-5472.CAN-13-2474. Epub 2013 Dec 18.

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