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Items: 1 to 20 of 111

1.

The DNA damage- and transcription-associated protein paxip1 controls thymocyte development and emigration.

Callen E, Faryabi RB, Luckey M, Hao B, Daniel JA, Yang W, Sun HW, Dressler G, Peng W, Chi H, Ge K, Krangel MS, Park JH, Nussenzweig A.

Immunity. 2012 Dec 14;37(6):971-85. doi: 10.1016/j.immuni.2012.10.007. Epub 2012 Nov 15.

2.

T-cell receptor α enhancer is inactivated in αβ T lymphocytes.

del Blanco B, Angulo Ú, Krangel MS, Hernández-Munain C.

Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):E1744-53. doi: 10.1073/pnas.1406551112. Epub 2015 Mar 23.

3.

TRIM28 mediates chromatin modifications at the TCRα enhancer and regulates the development of T and natural killer T cells.

Zhou XF, Yu J, Chang M, Zhang M, Zhou D, Cammas F, Sun SC.

Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):20083-8. doi: 10.1073/pnas.1214704109. Epub 2012 Nov 19.

4.

T cell factor-1 controls the lifetime of CD4+ CD8+ thymocytes in vivo and distal T cell receptor α-chain rearrangement required for NKT cell development.

Sharma A, Berga-Bolaños R, Sen JM.

PLoS One. 2014 Dec 23;9(12):e115803. doi: 10.1371/journal.pone.0115803. eCollection 2014.

5.

Distinct contracted conformations of the Tcra/Tcrd locus during Tcra and Tcrd recombination.

Shih HY, Krangel MS.

J Exp Med. 2010 Aug 30;207(9):1835-41. doi: 10.1084/jem.20100772. Epub 2010 Aug 9.

6.

A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation.

Seitan VC, Hao B, Tachibana-Konwalski K, Lavagnolli T, Mira-Bontenbal H, Brown KE, Teng G, Carroll T, Terry A, Horan K, Marks H, Adams DJ, Schatz DG, Aragon L, Fisher AG, Krangel MS, Nasmyth K, Merkenschlager M.

Nature. 2011 Aug 10;476(7361):467-71. doi: 10.1038/nature10312.

7.

IL-7 coordinates proliferation, differentiation and Tcra recombination during thymocyte β-selection.

Boudil A, Matei IR, Shih HY, Bogdanoski G, Yuan JS, Chang SG, Montpellier B, Kowalski PE, Voisin V, Bashir S, Bader GD, Krangel MS, Guidos CJ.

Nat Immunol. 2015 Apr;16(4):397-405. doi: 10.1038/ni.3122. Epub 2015 Mar 2.

8.

Specification of Vδ and Vα usage by Tcra/Tcrd locus V gene segment promoters.

Naik AK, Hawwari A, Krangel MS.

J Immunol. 2015 Jan 15;194(2):790-4. doi: 10.4049/jimmunol.1402423. Epub 2014 Dec 3.

9.

β-Catenin induces T-cell transformation by promoting genomic instability.

Dose M, Emmanuel AO, Chaumeil J, Zhang J, Sun T, Germar K, Aghajani K, Davis EM, Keerthivasan S, Bredemeyer AL, Sleckman BP, Rosen ST, Skok JA, Le Beau MM, Georgopoulos K, Gounari F.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):391-6. doi: 10.1073/pnas.1315752111. Epub 2013 Dec 26.

10.
11.

PTIP promotes chromatin changes critical for immunoglobulin class switch recombination.

Daniel JA, Santos MA, Wang Z, Zang C, Schwab KR, Jankovic M, Filsuf D, Chen HT, Gazumyan A, Yamane A, Cho YW, Sun HW, Ge K, Peng W, Nussenzweig MC, Casellas R, Dressler GR, Zhao K, Nussenzweig A.

Science. 2010 Aug 20;329(5994):917-23. doi: 10.1126/science.1187942. Epub 2010 Jul 29.

12.

An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells.

D'Cruz LM, Knell J, Fujimoto JK, Goldrath AW.

Nat Immunol. 2010 Mar;11(3):240-9. doi: 10.1038/ni.1845. Epub 2010 Feb 14. Erratum in: Nat Immunol. 2010 Jul;11(7):644.

13.

Recent insights into the transcriptional control of the Tcra/Tcrd locus by distant enhancers during the development of T-lymphocytes.

Hernández-Munain C.

Transcription. 2015;6(4):65-73. doi: 10.1080/21541264.2015.1078429. Review.

14.

ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes.

Matei IR, Gladdy RA, Nutter LM, Canty A, Guidos CJ, Danska JS.

Blood. 2007 Mar 1;109(5):1887-96. Epub 2006 Oct 31.

15.

Noncoding transcription controls downstream promoters to regulate T-cell receptor alpha recombination.

Abarrategui I, Krangel MS.

EMBO J. 2007 Oct 17;26(20):4380-90. Epub 2007 Sep 20.

16.
17.

Regulation of T cell receptor alpha gene assembly by a complex hierarchy of germline Jalpha promoters.

Hawwari A, Bock C, Krangel MS.

Nat Immunol. 2005 May;6(5):481-9. Epub 2005 Apr 3.

18.

Long-distance regulation of fetal V(δ) gene segment TRDV4 by the Tcrd enhancer.

Hao B, Krangel MS.

J Immunol. 2011 Sep 1;187(5):2484-91. doi: 10.4049/jimmunol.1100468. Epub 2011 Jul 22.

19.

Development of innate CD4+ and CD8+ T cells in Itk-deficient mice is regulated by distinct pathways.

Prince AL, Kraus Z, Carty SA, Ng C, Yin CC, Jordan MS, Schwartzberg PL, Berg LJ.

J Immunol. 2014 Jul 15;193(2):688-99. doi: 10.4049/jimmunol.1302059. Epub 2014 Jun 18.

20.

The pre-TCR signal induces transcriptional silencing of the TCRγ locus by reducing the recruitment of STAT5 and Runx to transcriptional enhancers.

Tani-Ichi S, Satake M, Ikuta K.

Int Immunol. 2011 Sep;23(9):553-63. doi: 10.1093/intimm/dxr055. Epub 2011 Jul 12.

PMID:
21750145

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